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Protein Ontology Report - ACVR1B

PR:000000068 - http://purl.obolibrary.org/obo/PR_000000068
Ontology Information
PRO ID PR:000000068 Show OBO stanza / PAF
PRO name activin receptor type-1B
Synonyms
PRO-short-label: EXACT: ACVR1B
Gene-based: RELATED: ACVRLK4 | ALK4
Other: EXACT: ACTR-IB | ALK-4 | SKR2 | activin receptor type IB | activin receptor-like kinase 4 | serine/threonine-protein kinase receptor R2
Definition A TGF-beta superfamily receptor type-1 that is a translation product of the human ACVR1B gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000006 TGF-beta superfamily receptor type-1
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 3 organism-sequence 6
modification 3 organism-modification 4
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036437
hACVR1B/iso:1/Phos:1
acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:12065756
enables GO:0046332 SMAD binding with PR:000000066 R-SMAD(TGFB) PMID:12065756
enables GO:0016361 activin receptor activity, type I PMID:8622651
located_in GO:0005886 plasma membrane PMID:8397373
located_in GO:0009986 cell surface PMID:12665502
PR:P36896-1
hACVR1B/iso:1
acts_upstream_of_or_within GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PMID:11069203
PR:P36896-2
hACVR1B/iso:2
enables NOT GO:0016361 activin receptor activity, type I PMID:11117535, PMID:8636304
located_in GO:0005886 plasma membrane PMID:11117535, PMID:8636304
PR:P36896-3
hACVR1B/iso:3
enables NOT GO:0016361 activin receptor activity, type I PMID:11117535, PMID:8636304
located_in GO:0005886 plasma membrane PMID:11117535, PMID:8636304
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0009986 cell surface PR:000036437 hACVR1B/iso:1/Phos:1

PMID:12665502
GO:0005886 plasma membrane PR:000036437 hACVR1B/iso:1/Phos:1

PMID:8397373
PR:P36896-2 hACVR1B/iso:2

PMID:11117535, PMID:8636304
PR:P36896-3 hACVR1B/iso:3

PMID:11117535, PMID:8636304

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