PRO Entry Report - PR:000003390

Protein Forms Annotations

Ontology Information

PRO ID

PR:000003390 Show OBO stanza / PAF

PRO name

RNA-binding protein FXR1

Synonyms

PRO-short-label:	EXACT:	FXR1
Gene-based:	RELATED:	Fxr1h
Other:	EXACT:	FXR1p \| fragile X mental retardation syndrome-related protein 1

Definition

A fragile X-related protein that is a translation product of the human FXR1 gene or a 1:1 ortholog thereof. [MGI:104860, PRO:HJD]

PRO Category

gene

Parent

PR:000003222 fragile X-related protein

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Term Hierarchy Visualization

DAG

OLS

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:Q61584-2 mFXR1/iso:A	enables	NOT GO:0002151 G-quadruplex RNA binding	MGI:3699977, PMID:17170008
PR:Q61584-1 mFXR1/iso:E	enables	GO:0002151 G-quadruplex RNA binding	MGI:3699977, PMID:17170008
	located_in	GO:0005737 cytoplasm	MGI:3760313, PMID:11178106
	located_in	GO:0005634 nucleus	PMID:11178106
	part_of	GO:0043034 costamere	PMID:15128702
	part_of	GO:0005844 polysome	MGI:3760313, PMID:11178106
PR:Q61584-7 mFXR1/iso:G	located_in	GO:0005634 nucleus	PMID:11178106
	located_in	GO:0005737 cytoplasm	MGI:3760313, PMID:11178106
	part_of	GO:0005844 polysome	MGI:3760313, PMID:11178106
PR:Q61584-6 mFXR1/iso:F	located_in	GO:0005737 cytoplasm	PMID:11178106
	located_in	GO:0005634 nucleus	PMID:11178106
	part_of	GO:0005844 polysome	PMID:11178106
PR:Q61584-5 mFXR1/iso:D	acts_upstream_of_or_within	GO:0017148 negative regulation of translation	MGI:3573966, PMID:15548538
	enables	NOT GO:0002151 G-quadruplex RNA binding	MGI:3699977, PMID:17170008
	enables	GO:0003730 mRNA 3'-UTR binding	MGI:3573966, PMID:15548538
	located_in	GO:0005737 cytoplasm	MGI:3573966, PMID:15548538

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