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Protein Ontology Report - mSHH/Clv:Nter/2*Lipid:1

PR:000037269 - http://purl.obolibrary.org/obo/PR_000037269
Ontology Information
PRO ID PR:000037269 Show OBO stanza / PAF
PRO name sonic hedgehog protein N-product dually lipidated 1 (mouse)
Synonyms
PRO-short-label: mSHH/Clv:Nter/2*Lipid:1
PRO-proteoform-std: UniProtKB:Q62226, 25-198, Cys-25, MOD:00069|Gly-198, MOD:00314
Definition A sonic hedgehog protein N-product in mouse that has been further modified on the N-terminal Cys residue by palmitoylation and the C-terminal Gly residue by cholesterylation. UniProtKB:Q62226, 25-198, Cys-25, MOD:00069, Gly-198, MOD:00314. [PMID:15075292, PMID:8824192, PRO:KRC]
PRO Category organism-modification
Parent PR:000037273 sonic hedgehog protein N-product
Taxon NCBITaxon:10090 Mus musculus
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000037269
mSHH/Clv:Nter/2*Lipid:1
Cys-25, MOD:00069|Gly-198, MOD:00314
participates_in GO:0030326 embryonic limb morphogenesis MGI:2135419, PMID:11389830
participates_in GO:0042733 embryonic digit morphogenesis MGI:3039193, PMID:15075292
participates_in GO:0009952 anterior/posterior pattern specification MGI:2135419, PMID:11389830
participates_in GO:0007224 smoothened signaling pathway MGI:3039193, PMID:15075292
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0042733 embryonic digit morphogenesis PR:000037269 mSHH/Clv:Nter/2*Lipid:1
Cys-25, MOD:00069|Gly-198, MOD:00314
MGI:3039193, PMID:15075292
GO:0007224 smoothened signaling pathway PR:000037269 mSHH/Clv:Nter/2*Lipid:1
Cys-25, MOD:00069|Gly-198, MOD:00314
MGI:3039193, PMID:15075292
GO:0030326 embryonic limb morphogenesis PR:000037269 mSHH/Clv:Nter/2*Lipid:1
Cys-25, MOD:00069|Gly-198, MOD:00314
MGI:2135419, PMID:11389830
GO:0009952 anterior/posterior pattern specification PR:000037269 mSHH/Clv:Nter/2*Lipid:1
Cys-25, MOD:00069|Gly-198, MOD:00314
MGI:2135419, PMID:11389830

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