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Protein Ontology Report - ptx homeobox protein

PR:000000022 - http://purl.obolibrary.org/obo/PR_000000022
Ontology Information
PRO ID PR:000000022 Show OBO stanza / PAF
PRO name ptx homeobox protein
Definition A protein that has a core domain composition consisting of an N-terminal K50 class Homeobox domain (Pfam:PF00046) and a C-terminal OAR domain (Pfam:PF03826). The homeobox domain consists of a self-folding, stable protein domain of 60 amino acids in which position 50 can confer a distinct DNA binding specificity. The K50 class of homeodomains recognizes a consensus DNA sequence of TAATCC. Homeodomain-containing proteins are known to play important roles in such diverse activities as embryonic pattern formation, cell-type specification, and differentiation. [PMID:15895993]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000000022
ptx homeobox protein
acts_upstream_of_or_within GO:0007275 multicellular organism development PIRSF:PIRSF000563
acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PIRSF:PIRSF000563
enables GO:0003700 DNA-binding transcription factor activity PIRSF:PIRSF000563

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