PRO Entry Report - PR:000000216

Protein Ontology Report - INHBA

PR:000000216 - http://purl.obolibrary.org/obo/PR_000000216

Protein Forms Annotations

Ontology Information

PRO ID

PR:000000216 Show OBO stanza / PAF

PRO name

activin/inhibin beta A chain

Synonyms

PRO-short-label:	EXACT:	INHBA
Other:	EXACT:	EDF \| activin beta-A chain \| erythroid differentiation protein

Definition

An activin/inhibin beta subunit that is a translation product of the human INHBA gene or a 1:1 ortholog thereof. [PRO:CNA]

PRO Category

gene

Parent

PR:000000072 activin/inhibin beta subunit

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
gene	1	organism-gene	4
sequence	1	organism-sequence	2
modification	3	organism-modification	3
union	0

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000036539 mINHBA/iso:1/Clv:1	enables	GO:0046983 protein dimerization activity	PMID:2133547
PR:000036539 mINHBA/iso:1/Clv:1	enables	GO:0005102 signaling receptor binding	PMID:1646080, PMID:7577669
PR:000036540 hINHBA/iso:1/Clv:1	acts_upstream_of_or_within	GO:0007267 cell-cell signaling	PMID:12456957
	acts_upstream_of_or_within	GO:0007166 cell surface receptor signaling pathway	PMID:12456957
	acts_upstream_of_or_within	GO:0030154 cell differentiation	PMID:12456957
	acts_upstream_of_or_within	GO:0032925 regulation of activin receptor signaling pathway	PMID:9884026
	acts_upstream_of_or_within	GO:0009605 response to external stimulus	PMID:10320815
	enables	GO:0046983 protein dimerization activity	PMID:1537316
	enables	GO:0005102 signaling receptor binding	PMID:7890768
	located_in	GO:0005576 extracellular region	PMID:12213882, PMID:2575216
	part_of	GO:0043512 inhibin A complex with PR:000036608 hINHA/iso:1/ClvNGlyco:2	PMID:17456790, PMID:7890768
	part_of	GO:0032991 protein-containing complex	PMID:12960042
	part_of	GO:0043509 activin A complex	PMID:7890768
PR:P08476-1 hINHBA/iso:1	acts_upstream_of_or_within	GO:0001541 ovarian follicle development	PMID:9166111
	acts_upstream_of_or_within	GO:0007165 signal transduction	PMID:3267209
	acts_upstream_of_or_within	GO:0007267 cell-cell signaling	PMID:12456957
	acts_upstream_of_or_within	GO:0050789 regulation of biological process	PMID:12419948, PMID:3122219
	acts_upstream_of_or_within	GO:0007399 nervous system development	PMID:10320815
	acts_upstream_of_or_within	GO:0030154 cell differentiation	PMID:12456957

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005576 extracellular region	PR:000036540 hINHBA/iso:1/Clv:1	PMID:12213882, PMID:2575216

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