Protein Ontology Report - hTGFB1/var:H222D/Clv:2 PR:000000624 - http://purl.obolibrary.org/obo/PR_000000624

Ontology Information
PRO ID	PR:000000624 Show OBO stanza / PAF / GPI
PRO name	TGF-beta 1 sequence variant H222D cleaved 2 (human)
Synonyms	PRO-short-label: EXACT: hTGFB1/var:H222D/Clv:2 PRO-proteoform-std: EXACT: UniProtKB:P01137, 30-278, His-222, CHEBI:29958 Other: EXACT: TGF-beta 1 sequence variant 5 cleaved 2 (human)
Definition	A TGF-beta 1 sequence variant H222D, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, His-222, CHEBI:29958. [PMID:11278244, PRO:CNA, PRO:DAN]
PRO Category	organism-modification
Parent	PR:000021905 TGF-beta 1 sequence variant H222D, signal peptide removed form (human)
Taxon	NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization	DAG     OLS     Cytoscape

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PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View
PRO Term GO Annotation Evidence PR:000000624 hTGFB1/var:H222D/Clv:2 His-222, CHEBI:29958 has_agent SO:0001601 conformational_change_variant PMID:11278244 has_agent SO:0001561 polypeptide_partial_loss_of_function PMID:11278244

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