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Protein Ontology Report - KCNA3

PR:000000811 - http://purl.obolibrary.org/obo/PR_000000811
Ontology Information
PRO ID PR:000000811 Show OBO stanza / PAF
PRO name voltage-gated potassium channel subunit KCNA3
Synonyms
PRO-short-label: EXACT: KCNA3
Gene-based: RELATED: HGK5
Other: EXACT: HLK3 | HPCN3 | MK3 | voltage-gated K(+) channel HuKIII | voltage-gated potassium channel subunit Kv1.3
Definition A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA3 gene or a 1:1 ortholog thereof. The Kv1.3 channel is involved in maintaining membrane potential and calcium signaling in lymphocytes and oligodendrocytes. It can coassemble with other Kv1 subunits. [PRO:CNA]
PRO Category gene
Parent PR:000000709 shaker-related voltage-gated potassium channel alpha subunit
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 1
modification 3 organism-modification 2
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P22001-1
hKCNA3/iso:1
capable_of GO:0005251 delayed rectifier potassium channel activity PMID:1986382
located_in GO:0005743 mitochondrial inner membrane PMID:15632141
located_in GO:0005886 plasma membrane PMID:15632141
PR:000036639
hKCNA3/iso:1/Phos:1
capable_of GO:0015271 outward rectifier potassium channel activity decreased relative to PR:000002682 KCNA3/iso:1/UnMod PMID:9989602
PR:000044708
hKCNA3/iso:1/UnMod
capable_of GO:0015271 outward rectifier potassium channel activity PMID:9989602
Molecular Function GO Term Protein Forms & Complexes Evidence
GO:0015271 outward rectifier potassium channel activity PR:000036639 hKCNA3/iso:1/Phos:1

decreased relative to PR:000002682 KCNA3/iso:1/UnMod
PMID:9989602
PR:000044708 hKCNA3/iso:1/UnMod

PMID:9989602
GO:0005251 delayed rectifier potassium channel activity PR:P22001-1 hKCNA3/iso:1

PMID:1986382
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005743 mitochondrial inner membrane PR:P22001-1 hKCNA3/iso:1

PMID:15632141
GO:0005886 plasma membrane PR:P22001-1 hKCNA3/iso:1

PMID:15632141

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