PRO ID |
PR:000001012
Show OBO stanza
|
PRO name |
integrin alpha-M |
Synonyms |
PRO-short-label: |
EXACT: |
ITGAM |
Gene-based: |
RELATED: |
CD11B | CR3A |
Other: |
EXACT: |
CD11 antigen-like family member B | CD11b | CR-3 alpha chain | cell surface glycoprotein MAC-1 subunit alpha | leukocyte adhesion receptor MO1 | neutrophil adherence receptor |
|
Definition |
An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1.
[UniProtKB:P11215]
|
Comment |
Requested by=CL. |
PRO Category |
gene |
Parent |
PR:000001005 integrin alpha with A domain |
Terms by PRO Category |
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Organism-Independent |
Organism-Specific |
Category |
Number of Terms |
Category |
Number of Terms |
gene
|
1 |
organism-gene
|
3 |
sequence
|
0 |
organism-sequence
|
4 |
modification
|
1 |
organism-modification
|
1 |
union
|
0 |
|
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