Protein Ontology Report - SYK PR:000003065 - http://purl.obolibrary.org/obo/PR_000003065

Ontology Information
PRO ID	PR:000003065 Show OBO stanza / PAF
PRO name	tyrosine-protein kinase SYK
Synonyms	PRO-short-label: EXACT: SYK Other: EXACT: spleen tyrosine kinase
Definition	A SYK/ZAP-70 family tyrosine-protein kinase that is a translation product of the human SYK gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category	gene
Parent	PR:000003063 SYK/ZAP-70 family tyrosine-protein kinase
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Independent Organism-Specific Category Number of Terms Category Number of Terms gene 1 organism-gene 4 sequence 1 organism-sequence 5 modification 2 organism-modification 11 union 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	IUPHARobj:2230

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All gene organism-gene sequence organism-sequence modification organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000025834 mSYK/iso:1/Phos:1 Tyr-317/Tyr-342/Tyr-346, MOD:00048 acts_upstream_of_or_within GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis PMID:15536084 enables GO:0043548 phosphatidylinositol 3-kinase binding with PR:P27986 hPIK3R1 PMID:15536084 enables GO:0019901 protein kinase binding with PR:P09769 hFGR PMID:15536084 enables GO:0031625 ubiquitin protein ligase binding with PR:P09769 hFGR PMID:15536084

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