PRO Entry Report - PR:000003469

Protein Ontology Report - EGR2

PR:000003469 - http://purl.obolibrary.org/obo/PR_000003469

Protein Forms Annotations

Ontology Information

PRO ID

PR:000003469 Show OBO stanza / PAF

PRO name

early growth response protein 2

Synonyms

PRO-short-label:	EXACT:	EGR2
Gene-based:	RELATED:	KROX20 \| Krox-20 \| Zfp-25
Other:	EXACT:	AT591 \| E3 SUMO-protein transferase ERG2 \| EGR-2 \| zinc finger protein Krox-20

Definition

A protein that is a translation product of the human EGR2 gene or a 1:1 ortholog thereof. [PRO:CNA]

Comment

Requested by=CL.

PRO Category

gene

Parent

PR:000000001 protein

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
gene	1	organism-gene	4
sequence	2	organism-sequence	6
modification	0	organism-modification	0
union	0

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:P08152-1 mEGR2/iso:Long	acts_upstream_of_or_within	GO:0045944 positive regulation of transcription by RNA polymerase II	PMID:8093858
	acts_upstream_of_or_within	GO:0007622 rhythmic behavior	PMID:8893031
	enables	GO:0003700 DNA-binding transcription factor activity	PMID:8093858
	enables	GO:0003677 DNA binding	PMID:8093858, PMID:8895582
	located_in	GO:0005634 nucleus	PMID:15282162
PR:P08152-2 mEGR2/iso:Short	enables	GO:0005515 protein binding with PR:Q8C5D8-1 mPIAS2/iso:1	MGI:3629292, PMID:16675951
PR:P08152-2 mEGR2/iso:Short	located_in	GO:0005634 nucleus	MGI:3629292, PMID:16675951
PR:P08152 mEGR2	acts_upstream_of_or_within	GO:0008045 motor neuron axon guidance	PMID:9806922
	acts_upstream_of_or_within	GO:0021612 facial nerve structural organization	PMID:9806922
	acts_upstream_of_or_within	GO:0014037 Schwann cell differentiation	PMID:16136673
	acts_upstream_of_or_within	GO:0006355 regulation of DNA-templated transcription	PMID:16136673
	acts_upstream_of_or_within	GO:0021569 rhombomere 3 development	PMID:9806922
	acts_upstream_of_or_within	GO:0021660 rhombomere 3 formation	PMID:7903221
	acts_upstream_of_or_within	GO:0042552 myelination	PMID:10704452
	acts_upstream_of_or_within	GO:0042552 myelination	PMID:16136673
	acts_upstream_of_or_within	GO:0007622 rhythmic behavior	PMID:8893031
	acts_upstream_of_or_within	GO:0006355 regulation of DNA-templated transcription	PMID:10704452
	acts_upstream_of_or_within	GO:0021666 rhombomere 5 formation	PMID:7903221
	acts_upstream_of_or_within	GO:0030278 regulation of ossification	PMID:8565822

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005634 nucleus	PR:P08152-1 mEGR2/iso:Long	PMID:15282162
GO:0005634 nucleus	PR:P08152-2 mEGR2/iso:Short	MGI:3629292, PMID:16675951

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