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Protein Ontology Report - hTGFB1/iso:1/mature

PR:000025927 - http://purl.obolibrary.org/obo/PR_000025927
Ontology Information
PRO ID PR:000025927 Show OBO stanza / PAF / GPI
PRO name TGF-beta 1 isoform 1 mature form (human)
Synonyms
PRO-short-label: EXACT: hTGFB1/iso:1/mature
PRO-proteoform-std: EXACT: UniProtKB:P01137-1, 279-390
PRO-proteoform-ftid: EXACT: PRO_0000033763
Definition A TGF-beta 1 isoform 1 mature form in human. UniProtKB:P01137-1, 279-390. [PMID:3162913]
PRO Category organism-modification
Parent PR:000000616 TGF-beta 1 isoform 1 mature form
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hTGFB1/iso:1/mature forms found in complexes
hTGFB1/iso:1/mature Component Complexes
PR:000025927 hTGFB1/iso:1/mature PR:000025926 dimeric TGF-beta 1 (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000025927
hTGFB1/iso:1/mature
acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:9918798
acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:8471846
enables GO:0042803 protein homodimerization activity PMID:3162913, PMID:8471846
located_in GO:0031012 extracellular matrix PMID:8294500
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0031012 extracellular matrix PR:000025927 hTGFB1/iso:1/mature

PMID:8294500

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