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Protein Ontology Report - mnt-msin3-hdac1 complex

PR:000026023 - http://purl.obolibrary.org/obo/PR_000026023
Ontology Information
PRO ID PR:000026023 Show OBO stanza / PAF
PRO name mnt-msin3-hdac1 complex
Definition A transcriptional repressor complex that is composed of the unphosphorylated form of Max-binding protein MNT and one of the sin3 proteins. [PMID:16103876, PMID:17419941, PRO:CNA]
PRO Category complex
Parent GO:0032991 protein-containing complex
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
complex 1 organism-complex 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000026023 PR:000026027 paired amphipathic helix protein Sin3 paired amphipathic helix protein Sin3 A protein that is a translation product of the human SIN3, SIN3A or SIN3B genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The core domain architecture consists of 3 copies of the Paired amphipathic helix repeat (Pfam:PF02671) domain and one or two copies of the Histone deacetylase interacting (Pfam:PF08295) domain. [PMID:19505602, PRO:CNA, PRO:DAN]
PR:000008478 histone deacetylase 1 HDAC1 A protein that is a translation product of the human HDAC1 gene or a 1:1 ortholog thereof. [PRO:DNx]
PR:000026017 Max-binding protein MNT isoform 1 unmodified form MNT/iso:1/UnMod A Max-binding protein MNT isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage. [PRO:CNA]


Functional Annotation
PRO Term GO Annotation Evidence
PR:000026023
mnt-msin3-hdac1 complex
enables GO:0004407 histone deacetylase activity PMID:16103876
enables GO:0070888 E-box binding PMID:16103876
enables GO:0045892 negative regulation of DNA-templated transcription PMID:16103876

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