PRO Entry Report - PR:000026481

Protein Ontology Report - hMAPK7/iso:1/Phos:1

PR:000026481 - http://purl.obolibrary.org/obo/PR_000026481

Protein Forms Annotations

Ontology Information

PRO ID

PR:000026481 Show OBO stanza / PAF / GPI

PRO name

mitogen-activated protein kinase 7 isoform 1 phosphorylated 1 (human)

Synonyms

PRO-short-label:	EXACT:	hMAPK7/iso:1/Phos:1
PRO-proteoform-std:	EXACT:	UniProtKB:Q13164-1, Thr-28/Thr-219/Thr-733, MOD:00047\|Ser-421/Ser-433/Ser-496/Ser-731, MOD:00046\|Tyr-221, MOD:00048
Other:	RELATED:	BMK1 active form

Definition

A mitogen-activated protein kinase 7 isoform 1 phosphorylated 1 in human. UniProtKB:Q13164-1, Thr-28/Thr-219/Thr-733, MOD:00047, Tyr-221, MOD:00048, Ser-421/Ser-433/Ser-496/Ser-731, MOD:00046. [PMID:12628002, PMID:20832753, PRO:CNA]

Comment

Kinase=("BMK1"; PR:000048327; Thr-28/Ser-421/Ser-433/Ser-496/Ser-731/Thr-733).

PRO Category

organism-modification

Parent

PR:000026479 mitogen-activated protein kinase 7 isoform 1 phosphorylated 1

Taxon

NCBITaxon:9606 Homo sapiens

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000026481 hMAPK7/iso:1/Phos:1 Thr-28/Thr-219/Thr-733, MOD:00047\|Tyr-221, MOD:00048\|Ser-421/Ser-433/Ser-496/Ser-731, MOD:00046	acts_upstream_of_or_within	GO:0008284 positive regulation of cell population proliferation	PMID:20832753
	enables	GO:0005515 protein binding with PR:P29590-1 hPML/iso:1	PMID:20832753
	enables	GO:0004707 MAP kinase activity	PMID:20832753
	located_in	GO:0005634 nucleus	PMID:20832753

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005634 nucleus	PR:000026481 hMAPK7/iso:1/Phos:1 Thr-28/Thr-219/Thr-733, MOD:00047\|Tyr-221, MOD:00048\|Ser-421/Ser-433/Ser-496/Ser-731, MOD:00046	PMID:20832753

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