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Protein Ontology Report - (pIRF7)*2

PR:000027085 -
Ontology Information
PRO ID PR:000027085 Show OBO stanza / PAF
PRO name IRF7-P:IRF7-P complex
PRO-short-label: EXACT: (pIRF7)*2
Other: EXACT: IRF7pIRF7p
Definition A protein-containing complex that is composed of a homodimer of phosphorylated IRF-7. [PMID:18068231, PRO:CNA, TLR:AMM]
Comment Requested GO term.Requested by=TLR.
PRO Category complex
Parent GO:0032991 protein-containing complex
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
complex 1 organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000027086 PR:000027082 interferon regulatory factor 7 isoform 1 phosphorylated 1 (human) hIRF7/iso:1/Phos:1 An interferon regulatory factor 7 isoform 1 phosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046. [PMID:10893229, PMID:14517278, TLR:AMM] 2

Functional Annotation
PRO Term GO Annotation Evidence
IRF7-P:IRF7-P complex (human)
acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894
acts_upstream_of_or_within GO:0002753 cytosolic pattern recognition receptor signaling pathway Reactome:REACT_7146
enables GO:0003700 DNA-binding transcription factor activity PMID:11073981
located_in GO:0005654 nucleoplasm Reactome:REACT_21689
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005654 nucleoplasm PR:000027086 IRF7-P:IRF7-P complex (human)