PRO Entry Report - PR:000027085

Complex Forms Complex Subunits Annotations

Ontology Information

PRO ID

PR:000027085 Show OBO stanza / PAF

PRO name

IRF7-P:IRF7-P complex

Synonyms

PRO-short-label:	EXACT:	(pIRF7)*2
Other:	EXACT:	IRF7pIRF7p

Definition

A protein-containing complex that is composed of a homodimer of phosphorylated IRF-7. [PMID:18068231, PRO:CNA, TLR:AMM]

Comment

Requested GO term.Requested by=TLR.

PRO Category

complex

Parent

GO:0032991 protein-containing complex

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
complex	1	organism-complex	1

Term Hierarchy Visualization

DAG

OLS

Complex Forms

PRO ID & Category Annotation Subunits	Name	Short Label	Definition & Comment

Complex Subunits

Complex	PRO ID	Name	Short Label	Definition	Number in Complex
PR:000027086	PR:000027082	interferon regulatory factor 7 isoform 1 phosphorylated 1 (human)	hIRF7/iso:1/Phos:1	An interferon regulatory factor 7 isoform 1 phosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046. [PMID:10893229, PMID:14517278, TLR:AMM]	2

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:000027086 IRF7-P:IRF7-P complex (human)	acts_upstream_of_or_within	GO:0002756 MyD88-independent toll-like receptor signaling pathway	Reactome:REACT_6809
	acts_upstream_of_or_within	GO:0034142 toll-like receptor 4 signaling pathway	Reactome:REACT_6894
	acts_upstream_of_or_within	GO:0002753 cytosolic pattern recognition receptor signaling pathway	Reactome:REACT_7146
	enables	GO:0003700 DNA-binding transcription factor activity	PMID:11073981
	located_in	GO:0005654 nucleoplasm	Reactome:REACT_21689

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005654 nucleoplasm	PR:000027086 IRF7-P:IRF7-P complex (human)	Reactome:REACT_21689

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