PRO Entry Report - PR:000035373

Protein Forms Complex Annotations

Ontology Information

PRO ID

PR:000035373 Show OBO stanza / PAF / GPI

PRO name

mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form (human)

Synonyms

PRO-short-label:

EXACT:

hBUB1B/PhosRes-

Definition

A mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form in human. [PRO:CNA]

PRO Category

organism-modification

Parent

PR:000035372 mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form

Taxon

Term Hierarchy Visualization

DAG

OLS

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

hBUB1B/PhosRes- forms found in complexes

hBUB1B/PhosRes- Component	Complexes
PR:000035373 hBUB1B/PhosRes-	PR:000035579 BUB1:unphosphoBUB1B complex (human)

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:000035373 hBUB1B/PhosRes-	acts_upstream_of_or_within	GO:0033673 negative regulation of kinase activity	PMID:19503101
	acts_upstream_of_or_within	GO:0001933 negative regulation of protein phosphorylation	PMID:22801780
	acts_upstream_of_or_within	GO:0010826 negative regulation of centrosome duplication	PMID:19503101
	enables	GO:0005515 protein binding with PR:000035669 hPLK1/PhosRes-	PMID:19503101
	located_in	GO:0000776 kinetochore	PMID:22801780
	located_in	GO:0005813 centrosome	PMID:19503101

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005813 centrosome	PR:000035373 hBUB1B/PhosRes-	PMID:19503101
GO:0000776 kinetochore	PR:000035373 hBUB1B/PhosRes-	PMID:22801780

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