A protein-containing complex that is composed of unanchored K63-linked polyubiquitin, the components of the tak 1 complex (tak1 and tab proteins), polyubiquitinated traf6, ticam1 and either activated Toll-like receptor 3 (TLR3) or activated Toll-like receptor 4 (TLR4) with ticam2.
[PRO:DAN, Reactome:R-HSA-936954]