PRO Entry Report - PR:000036408

Protein Forms Annotations

Ontology Information

PRO ID

PR:000036408 Show OBO stanza / PAF / GPI

PRO name

TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human)

Synonyms

PRO-short-label:	EXACT:	hTGFBR2/iso:RII-1/SigPep-
PRO-proteoform-std:	EXACT:	UniProtKB:P37173-1, 23-567
PRO-proteoform-ftid:	EXACT:	PRO_0000024426
Other:	EXACT:	TGF-beta receptor type-2 isoform 1, signal peptide removed form (human) \| hTGFBR2/iso:1/SigPep-

Definition

A TGF-beta receptor type-2 isoform RII-1, signal peptide removed form in human. UniProtKB:P37173-1, 23-567. [PMID:11483955, PMID:11850637, PMID:1310899, PMID:1850637, PMID:8774881, PRO:CNA]

PRO Category

organism-modification

Parent

PR:000000409 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form

Taxon

Term Hierarchy Visualization

DAG

OLS

Related Cross References
DB identifiers	Reactome:R-HSA-170842

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:000036408 hTGFBR2/iso:RII-1/SigPep-	acts_upstream_of_or_within	GO:0007179 transforming growth factor beta receptor signaling pathway	PMID:11483955
	acts_upstream_of_or_within	GO:0007181 transforming growth factor beta receptor complex assembly	PMID:1310899, PMID:8774881
	enables	GO:0005026 transforming growth factor beta receptor activity, type II	PMID:11483955
	enables	GO:0005515 protein binding with PR:000000616 TGFB1/iso:1/mature	PMID:1310899
	enables	GO:0050431 transforming growth factor beta binding	PMID:11850637, PMID:1310899
	enables	GO:0005515 protein binding with PR:000000634 TGFB3/iso:1/Clv:1	PMID:1850637
	located_in	GO:0016020 membrane	PMID:1310899

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0016020 membrane	PR:000036408 hTGFBR2/iso:RII-1/SigPep-	PMID:1310899

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