PRO Entry Report - PR:000037508

Protein Ontology Report - hYAP1/iso:3/Phos:1

PR:000037508 - http://purl.obolibrary.org/obo/PR_000037508

Protein Forms Annotations

Ontology Information

PRO ID

PR:000037508 Show OBO stanza / PAF / GPI

PRO name

transcriptional coactivator YAP1 isoform 3 phosphorylated 1 (human)

Synonyms

PRO-short-label:	EXACT:	hYAP1/iso:3/Phos:1
PRO-proteoform-std:	EXACT:	UniProtKB:P46937-3, Tyr-357, MOD:00048

Definition

A transcriptional coactivator YAP1 isoform 3 (human) that has been phosphorylated on a Tyr residue at position 357. UniProtKB:P46937-3, Tyr-357, MOD:00048. [PMID:21214929, PMID:21945154, PRO:KER]

Comment

Kinase=("ABL1"; PR:P00519; Tyr-357).

PRO Category

organism-modification

Parent

PR:P46937-3 transcriptional coactivator YAP1 isoform 3 (human)

Taxon

NCBITaxon:9606 Homo sapiens

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000037508 hYAP1/iso:3/Phos:1 Tyr-357, MOD:00048	associated_with_disease_progression	DOID:10652 Alzheimer's disease	PMID:21562856
	associated_with_disease_suppression	DOID:162 cancer	PMID:21214929
	enables	GO:0005515 protein binding increased relative to PR:000037507 hYAP1/iso:3/UnPhos:1 with PR:O15350 hTP73	PMID:21214929, PMID:21562856
	located_in	GO:0005634 nucleus	PMID:21562856

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005634 nucleus	PR:000037508 hYAP1/iso:3/Phos:1 Tyr-357, MOD:00048	PMID:21562856

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