PRO Entry Report - PR:000037795

Protein Ontology Report - GAIT complex (mouse)

PR:000037795 - http://purl.obolibrary.org/obo/PR_000037795

Complex Forms Complex Subunits

Ontology Information

PRO ID

PR:000037795 Show OBO stanza / GPI

PRO name

GAIT complex (mouse)

Synonyms

Other:

EXACT:

IFN-gamma-activated inhibitor of translation complex (mouse) | gamma interferon-activated inhibitor of translation complex (mouse)

Definition

A heterotrimeric complex consisting of glutamyl-prolyl-tRNA synthetase (EPRS), ribosomal protein L13a, and glyceraldehyde-3-phosphate dehydrogenase (GAPDH). [PMID:23071094, PRO:HJD]

Comment

Note: Only phosphorylated forms of EPRS and L13a are in the complex.

PRO Category

organism-complex

Parent

GO:0097452 GAIT complex

Taxon

NCBITaxon:10090 Mus musculus

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Organism-Specific
Category	Number of Terms
organism-complex	1

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Complex Forms

PRO ID & Category Annotation Subunits	Name	Short Label	Definition & Comment

Complex Subunits

Complex	PRO ID	Name	Short Label	Definition
PR:000037795	PR:P16858	glyceraldehyde-3-phosphate dehydrogenase (mouse)	mGAPDH	A glyceraldehyde-3-phosphate dehydrogenase that is encoded in the genome of mouse. [OMA:P16858, PMID:23071094, PRO:HJD]
	PR:000037785	bifunctional glutamate/proline--tRNA ligase phosphorylated 1 (mouse)	mEPRS/Phos:1	A bifunctional glutamate/proline--tRNA ligase (mouse) that has been phosphorylated on a Ser residue in the noncatalytic linker connecting the synthetase cores in an IFN-gamma-dependent manner. UniProtKB:Q8CGC7, Ser-999, MOD:00046. [PMID:23071094, PRO:HJD]
	PR:000037782	60S ribosomal protein L13a, initiator methionine removed acetylated and phosphorylated 1 (mouse)	mRPL13A/InitMet-/AcPhos:1	A 60S ribosomal protein L13a, initiator methionine removed acetylated and phosphorylated 1 in mouse. Phosphorylation occurs upon activation of the DAPK-ZIPK cascade. UniProtKB:P19253, 2-203, Ala-2, MOD:00050\|Ser-77, MOD:00046. [ECO:0000305, PMID:23071094, PRO:HJD, UniProtKB:P19253]

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