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Protein Ontology Report - hLCK

PR:P06239 - http://purl.obolibrary.org/obo/PR_P06239
This page represents a class of proteins encompassing all the protein products of the LCK gene in Homo sapiens.
Ontology Information
PRO ID PR:P06239 Show OBO stanza / PAF / GPI
PRO name tyrosine-protein kinase Lck (human)
Synonyms
PRO-short-label: EXACT: hLCK
Gene-based: RELATED: LCK
Other: EXACT: LSK (human) | T cell-specific protein-tyrosine kinase (human) | leukocyte C-terminal Src kinase (human) | lymphocyte cell-specific protein-tyrosine kinase (human) | p56-LCK (human) | protein YT16 (human) | proto-oncogene Lck (human)
Definition A tyrosine-protein kinase Lck that is encoded in the genome of human. [PRO:DNx]
PRO Category organism-gene
Parent PR:000002998 tyrosine-protein kinase Lck
Gene Template HGNC:6524 LCK
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 3
organism-modification 4
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hLCK forms found in complexes
hLCK Component Complexes
PR:P06239 hLCK PR:000028449 CD4:Lck complex (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036619
hLCK/iso:1/Phos:1
Tyr-394/Tyr-505, MOD:00048
enables GO:0016301 kinase activity decreased relative to PR:000036622 hLCK/iso:1/Phos:2 PMID:9043947
PR:000036622
hLCK/iso:1/Phos:2
Tyr-394, MOD:00048
enables GO:0044877 protein-containing complex binding PMID:9043947
enables GO:0016301 kinase activity PMID:9043947

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