Protein Ontology Report - hLCK PR:P06239 - http://purl.obolibrary.org/obo/PR_P06239

This page represents a class of proteins encompassing all the protein products of the LCK gene in Homo sapiens.

Ontology Information
PRO ID	PR:P06239 Show OBO stanza / PAF / GPI
PRO name	tyrosine-protein kinase Lck (human)
Synonyms	PRO-short-label: EXACT: hLCK Gene-based: RELATED: LCK Other: EXACT: LSK (human) | T cell-specific protein-tyrosine kinase (human) | leukocyte C-terminal Src kinase (human) | lymphocyte cell-specific protein-tyrosine kinase (human) | p56-LCK (human) | protein YT16 (human) | proto-oncogene Lck (human)
Definition	A tyrosine-protein kinase Lck that is encoded in the genome of human. [PRO:DNx]
PRO Category	organism-gene
Parent	PR:000002998 tyrosine-protein kinase Lck
Gene Template	HGNC:6524 LCK
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 3 organism-modification 4
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	DTO:03100266, Reactome:R-HSA-167609, UniProtKB:P06239

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hLCK forms found in complexes
hLCK Component Complexes PR:P06239 hLCK PR:000028449 CD4:Lck complex (human)

Functional Annotation PRO Centric View GO Centric View
PRO Term GO Annotation Evidence PR:000036619 hLCK/iso:1/Phos:1 Tyr-394/Tyr-505, MOD:00048 enables GO:0016301 kinase activity decreased relative to PR:000036622 hLCK/iso:1/Phos:2 PMID:9043947 PR:000036622 hLCK/iso:1/Phos:2 Tyr-394, MOD:00048 enables GO:0044877 protein-containing complex binding PMID:9043947 enables GO:0016301 kinase activity PMID:9043947

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