Protein Ontology Report - hYAP1 PR:P46937 - http://purl.obolibrary.org/obo/PR_P46937

This page represents a class of proteins encompassing all the protein products of the YAP1 gene in Homo sapiens.

Ontology Information
PRO ID	PR:P46937 Show OBO stanza / PAF / GPI
PRO name	transcriptional coactivator YAP1 (human)
Synonyms	PRO-short-label: EXACT: hYAP1 Gene-based: RELATED: YAP1 | YAP65 Other: EXACT: Yes-associated protein 1 (human) | Yes-associated protein YAP65 homolog (human) | protein yorkie homolog (human)
Definition	A transcriptional coactivator YAP1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P46937]
PRO Category	organism-gene
Parent	PR:000017522 transcriptional coactivator YAP1
Gene Template	HGNC:16262 YAP1
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 9 organism-modification 6
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	Reactome:R-HSA-1253322, Reactome:R-HSA-1253345, UniProtKB:P46937

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000037507 hYAP1/iso:3/UnPhos:1 Tyr-357, PR:000026291 enables GO:0005515 protein binding with PR:O15350 hTP73 PMID:21214929, PMID:21562856 PR:000037510 hYAP1/Phos:1 Ser-127, MOD:00046 associated_with_disease_progression DOID:162 cancer PMID:21214929 associated_with_disease_suppression DOID:10652 Alzheimer's disease PMID:21945154 enables GO:0005515 protein binding decreased relative to PR:000037509 hYAP1/UnPhos:1 with PR:O15350 hTP73 PMID:21945154 enables GO:0005515 protein binding with PR:000003237 fam:14-3-3 PMID:21214929 PR:000037508 hYAP1/iso:3/Phos:1 Tyr-357, MOD:00048 associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:21562856 associated_with_disease_suppression DOID:162 cancer PMID:21214929 enables GO:0005515 protein binding increased relative to PR:000037507 hYAP1/iso:3/UnPhos:1 with PR:O15350 hTP73 PMID:21214929, PMID:21562856 located_in GO:0005634 nucleus PMID:21562856 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005634 nucleus PR:000037508 hYAP1/iso:3/Phos:1 Tyr-357, MOD:00048 PMID:21562856

top