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Protein Ontology Report - hYAP1

PR:P46937 -
This page represents a class of proteins encompassing all the protein products of the YAP1 gene in Homo sapiens.
Ontology Information
PRO ID PR:P46937 Show OBO stanza / PAF / GPI
PRO name transcriptional coactivator YAP1 (human)
PRO-short-label: EXACT: hYAP1
Gene-based: RELATED: YAP1 | YAP65
Other: EXACT: Yes-associated protein 1 (human) | Yes-associated protein YAP65 homolog (human) | protein yorkie homolog (human)
Definition A transcriptional coactivator YAP1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P46937]
PRO Category organism-gene
Parent PR:000017522 transcriptional coactivator YAP1
Gene Template HGNC:16262 YAP1
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Category Number of Terms
organism-gene 1
organism-sequence 9
organism-modification 6
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
Tyr-357, PR:000026291
enables GO:0005515 protein binding with PR:O15350 hTP73 PMID:21214929, PMID:21562856
Ser-127, MOD:00046
associated_with_disease_progression DOID:162 cancer PMID:21214929
associated_with_disease_suppression DOID:10652 Alzheimer's disease PMID:21945154
enables GO:0005515 protein binding decreased relative to PR:000037509 hYAP1/UnPhos:1 with PR:O15350 hTP73 PMID:21945154
enables GO:0005515 protein binding with PR:000003237 fam:14-3-3 PMID:21214929
Tyr-357, MOD:00048
associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:21562856
associated_with_disease_suppression DOID:162 cancer PMID:21214929
enables GO:0005515 protein binding increased relative to PR:000037507 hYAP1/iso:3/UnPhos:1 with PR:O15350 hTP73 PMID:21214929, PMID:21562856
located_in GO:0005634 nucleus PMID:21562856
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000037508 hYAP1/iso:3/Phos:1
Tyr-357, MOD:00048