Protein Ontology Report - mPITX2 PR:P97474 - http://purl.obolibrary.org/obo/PR_P97474

This page represents a class of proteins encompassing all the protein products of the Pitx2 gene in Mus musculus.

Ontology Information
PRO ID	PR:P97474 Show OBO stanza / PAF / GPI
PRO name	pituitary homeobox 2 (mouse)
Synonyms	PRO-short-label: EXACT: mPITX2 Gene-based: RELATED: Arp1 | Brx1 | Otlx2 | Pitx2 | Ptx2 | Rgs Other: EXACT: ALL1-responsive protein ARP1 (mouse) | BRX1 homeoprotein (mouse) | homeobox protein PITX2 (mouse) | orthodenticle-like homeobox 2 (mouse) | paired-like homeodomain transcription factor 2 (mouse) | paired-like homeodomain transcription factor Munc 30 (mouse) | solurshin (mouse)
Definition	A pituitary homeobox 2 that is encoded in the genome of mouse. [OMA:P97474, PRO:DNx]
PRO Category	organism-gene
Parent	PR:000000117 pituitary homeobox 2
Gene Template	MGI:109340 Pitx2
Taxon	NCBITaxon:10090 Mus musculus
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 6 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	UniProtKB:P97474

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:P97474-1 mPITX2/iso:Ptx2B acts_upstream_of_or_within GO:0007368 determination of left/right symmetry PMID:12397115 acts_upstream_of_or_within GO:0016055 Wnt signaling pathway PMID:12464179 part_of GO:0005667 transcription factor complex PMID:12464179, PMID:15385555 PR:P97474-3 mPITX2/iso:Ptx2A acts_upstream_of_or_within NOT GO:0007368 determination of left/right symmetry PMID:10585561 acts_upstream_of_or_within GO:0007266 Rho protein signal transduction PMID:11854422 acts_upstream_of_or_within GO:0031532 actin cytoskeleton reorganization PMID:11854422 acts_upstream_of_or_within GO:0043388 positive regulation of DNA binding MGI:3796777, PMID:18458156 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific MGI:3796777, PMID:18458156 enables GO:0005515 protein binding with PR:Q9JM73 mSRF MGI:3796777, PMID:18458156 enables GO:0008134 transcription factor binding PMID:15385555 enables GO:0003677 DNA binding MGI:3796777, PMID:18458156 enables GO:0003712 transcription coregulator activity MGI:3796777, PMID:18458156 located_in GO:0005634 nucleus MGI:3796777, PMID:18458156 located_in GO:0005634 nucleus PMID:11854422 PR:P97474-2 mPITX2/iso:Ptx2C acts_upstream_of_or_within GO:0009887 animal organ morphogenesis PMID:10585561 acts_upstream_of_or_within GO:0007368 determination of left/right symmetry PMID:9708732 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:10585561 acts_upstream_of_or_within GO:0007520 myoblast fusion MGI:3686567, PMID:16958127 acts_upstream_of_or_within GO:2000288 positive regulation of myoblast proliferation MGI:3686567, PMID:16958127 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005634 nucleus PR:P97474-3 mPITX2/iso:Ptx2A MGI:3796777, PMID:18458156 PR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422

top