Protein Ontology Report - mTICAM1 PR:Q80UF7 - http://purl.obolibrary.org/obo/PR_Q80UF7

This page represents a class of proteins encompassing all the protein products of the Ticam1 gene in Mus musculus.

Ontology Information
PRO ID	PR:Q80UF7 Show OBO stanza / PAF / GPI
PRO name	TIR domain-containing adapter molecule 1 (mouse)
Synonyms	PRO-short-label: EXACT: mTICAM1 Gene-based: RELATED: Ticam1 | Trif Other: EXACT: TICAM-1 (mouse) | TIR domain-containing adapter protein inducing IFN-beta (mouse) | Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta (mouse)
Definition	A TIR domain-containing adapter molecule 1 that is encoded in the genome of mouse. [OMA:Q80UF7, PRO:CNA]
PRO Category	organism-gene
Parent	PR:000001749 TIR domain-containing adapter molecule 1
Gene Template	MGI:2147032 Ticam1
Taxon	NCBITaxon:10090 Mus musculus
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 0 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	UniProtKB:Q80UF7

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mTICAM1 forms found in complexes

mTICAM1 Component Complexes PR:Q80UF7 mTICAM1 PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse) PR:Q80UF7 mTICAM1 PR:000036109 pel1:K63-poly-Ub-rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse) PR:Q80UF7 mTICAM1 PR:000037311 traf3:ticam1:activated TLR3 complex (mouse) PR:Q80UF7 mTICAM1 PR:000037308 ticam1:viral dsRNA:TLR3 complex (mouse) PR:Q80UF7 mTICAM1 PR:000036105 pel1:rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse) PR:Q80UF7 mTICAM1 PR:000036101 rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse) PR:Q80UF7 mTICAM1 PR:000036099 ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse) PR:Q80UF7 mTICAM1 PR:000036097 tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse) PR:Q80UF7 mTICAM1 PR:000036095 K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse) PR:Q80UF7 mTICAM1 PR:000036093 tbk1:K63-poly-Ub-tank:Ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse) PR:Q80UF7 mTICAM1 PR:000036090 tbk1:tank:ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse) PR:Q80UF7 mTICAM1 PR:000028683 traf3:ticam1:ticam2:activated TLR4 complex (mouse) PR:Q80UF7 mTICAM1 PR:000035710 traf6:ticam1:ticam2:activated TLR4 complex (mouse) PR:Q80UF7 mTICAM1 PR:000037471 traf6:ticam1:activated TLR3 complex (mouse) PR:Q80UF7 mTICAM1 PR:000037313 tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000035710 traf6:ticam1:ticam2:activated TLR4 complex (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:14530355 PR:000036101 rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 PR:000037311 traf3:ticam1:activated TLR3 complex (mouse) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:16306936, PMID:16306937 PR:000037308 ticam1:viral dsRNA:TLR3 complex (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:12539043 acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:12539043 PR:000028683 traf3:ticam1:ticam2:activated TLR4 complex (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:16306937 acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway PMID:16306937 PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:18222170 acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway PMID:18222170 located_in GO:0010008 endosome membrane PMID:18222170 PR:000037313 tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse) acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:12133833, PMID:17327220 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0010008 endosome membrane PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse) PMID:18222170

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