Protein Ontology Report - hSMURF2 PR:Q9HAU4 - http://purl.obolibrary.org/obo/PR_Q9HAU4

This page represents a class of proteins encompassing all the protein products of the SMURF2 gene in Homo sapiens.

Ontology Information
PRO ID	PR:Q9HAU4 Show OBO stanza / PAF / GPI
PRO name	E3 ubiquitin-protein ligase SMURF2 (human)
Synonyms	PRO-short-label: EXACT: hSMURF2 Gene-based: RELATED: SMURF2 Other: EXACT: HECT-type E3 ubiquitin transferase SMURF2 (human) | SMAD ubiquitination regulatory factor 2 (human) | SMAD-specific E3 ubiquitin-protein ligase 2 (human)
Definition	An E3 ubiquitin-protein ligase SMURF2 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q9HAU4]
PRO Category	organism-gene
Parent	PR:000000362 E3 ubiquitin-protein ligase SMURF2
Gene Template	HGNC:16809 SMURF2
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 1 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	Reactome:R-HSA-173537, Reactome:R-HSA-178202, UniProtKB:Q9HAU4

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:Q9HAU4 hSMURF2 acts_upstream_of_or_within GO:0017015 regulation of transforming growth factor beta receptor signaling pathway PMID:11016919, PMID:11158580, PMID:11163210, PMID:15862290 acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PMID:14755250 enables GO:0005515 protein binding with PR:Q9Y3C5 hRNF11 PMID:14755250 enables GO:0004842 ubiquitin-protein transferase activity PMID:14755250

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