Protein Ontology Report - mSTK11 PR:Q9WTK7 - http://purl.obolibrary.org/obo/PR_Q9WTK7

This page represents a class of proteins encompassing all the protein products of the Stk11 gene in Mus musculus.

Ontology Information
PRO ID	PR:Q9WTK7 Show OBO stanza / PAF / GPI
PRO name	serine/threonine-protein kinase STK11 (mouse)
Synonyms	PRO-short-label: EXACT: mSTK11 Gene-based: RELATED: Lkb1 | Stk11 Other: EXACT: LKB1 (mouse) | liver kinase B1 homolog (mouse) | mLKB1
Definition	A serine/threonine-protein kinase STK11 that is encoded in the genome of mouse. [OMA:Q9WTK7, PRO:DNx]
PRO Category	organism-gene
Parent	PR:000015740 serine/threonine-protein kinase STK11
Gene Template	MGI:1341870 Stk11
Taxon	NCBITaxon:10090 Mus musculus
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 3 organism-modification 5
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	UniProtKB:Q9WTK7

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mSTK11 forms found in complexes
mSTK11 Component Complexes PR:Q9WTK7-1 mSTK11/iso:1 PR:000025037 Stk11 isoform 1:Strada:Cab39 heterotrimer (mouse) PR:Q9WTK7-2 mSTK11/iso:2 PR:000025038 Stk11 isoform 2:Strada:Cab39 heterotrimer (mouse)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000036997 mSTK11/iso:1/UnPhos:1 Tyr-261/Tyr-365, PR:000026291 located_in GO:0005737 cytoplasm MGI:4439241, PMID:20142099 PR:000036893 mSTK11/iso:1/Phos:1 Tyr-261/Tyr-365, MOD:00048 located_in GO:0005634 nucleus MGI:4439241, PMID:20142099 PR:000036995 mSTK11/iso:1/Phos:2 Tyr-36/Tyr-261/Tyr-365, MOD:00048 acts_upstream_of_or_within GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation MGI:5003385, PMID:21487392 acts_upstream_of_or_within GO:0036399 TCR signalosome assembly MGI:5003385, PMID:21487392 part_of GO:0036398 TCR signalosome MGI:5003385, PMID:21487392 PR:Q9WTK7-2 mSTK11/iso:2 located_in GO:0005737 cytoplasm MGI:3836081, PMID:18854309 PR:Q9WTK7-1 mSTK11/iso:1 acts_upstream_of_or_within GO:0032147 activation of protein kinase activity MGI:3836081, PMID:18854309 located_in GO:0016020 membrane MGI:3836081, PMID:18854309 located_in GO:0005737 cytoplasm MGI:3836081, PMID:18854309 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0016020 membrane PR:Q9WTK7-1 mSTK11/iso:1 MGI:3836081, PMID:18854309 GO:0005634 nucleus PR:000036893 mSTK11/iso:1/Phos:1 Tyr-261/Tyr-365, MOD:00048 MGI:4439241, PMID:20142099 GO:0005737 cytoplasm PR:000036997 mSTK11/iso:1/UnPhos:1 Tyr-261/Tyr-365, PR:000026291 MGI:4439241, PMID:20142099 PR:Q9WTK7-1 mSTK11/iso:1 MGI:3836081, PMID:18854309 PR:Q9WTK7-2 mSTK11/iso:2 MGI:3836081, PMID:18854309

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