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Protein Ontology report - protein kinase C beta type (human)
PR:P05771 - http://purl.obolibrary.org/obo/PR_P05771
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:P05771   
  PRO nameprotein kinase C beta type (human) 
  Synonyms
PRO-Short-label: EXACT:hPRKCB
Gene-based: RELATED:PKCB | PRKCB | PRKCB1
Other: EXACT:PKC-B (human) | PKC-beta (human)
  Definition"A protein kinase C beta type that is encoded in the genome of human." [PRO:CNA, UniProtKB:P05771] 
  PRO Categoryorganism-gene 
  ParentPR:000003059 protein kinase C beta type
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:9395 PRKCB (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P05771
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P05771 protein kinase C beta type (human)
hPRKCB

organism-sequence


PR:P05771-1 protein kinase C beta type isoform Beta-I (human)
hPRKCB/iso:Beta-I
Yes
organism-sequence


PR:P05771-2 protein kinase C beta type isoform Beta-II (human)
hPRKCB/iso:Beta-II
Yes
organism-modification


PR:000049853 protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:1
Yes
organism-modification


PR:000049854 protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:1

organism-modification


PR:000049855 protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:2
Yes
organism-modification


PR:000049856 protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:2

organism-modification


PR:000048913 protein kinase C beta type, initiator methionine removed form (human)
hPRKCB/InitMet-

organism-modification


PR:000048914 protein kinase C beta type, initiator methionine removed phosphorylated 1 (human)
hPRKCB/InitMet-/Phos:1

organism-modification


PR:000048915 protein kinase C beta type, initiator methionine removed phosphorylated 2 (human)
hPRKCB/InitMet-/Phos:2

organism-modification


PR:000049853 protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:1
Yes
organism-modification


PR:000049854 protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:1

organism-modification


PR:000049855 protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:2
Yes
organism-modification


PR:000049856 protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:2

organism-modification


PR:000049887 protein kinase C beta type phosphorylated 1 (human)
hPRKCB/Phos:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000049853 hPRKCB/iso:Beta-II/InitMet-/Phos:1
UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047		 enablesincreased GO:0004674 protein serine/threonine kinase activity relative to PR:000049854 hPRKCB/iso:Beta-II/InitMet-/UnPhos:1 PMID:8749392
located_inGO:0005737 cytoplasm PMID:9756933
GO:0005886 plasma membrane PMID:9756933
PR:000049855 hPRKCB/iso:Beta-II/InitMet-/Phos:2
UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046		 acts_upstream_of_or_withinincreased GO:0006468 protein phosphorylation relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:8749392
enablesincreased GO:0001786 phosphatidylserine binding relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:9218480
increased GO:0005509 calcium ion binding relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:9218480
located_inincreased GO:0005737 cytoplasm relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:9756933
PR:P05771-1 hPRKCB/iso:Beta-I acts_upstream_of_or_withinNOT GO:0001666 response to hypoxia MGI_ref:3847400; PMID:18323529
located_inGO:0016020 membrane MGI_ref:3847400; PMID:18323529
PR:P05771-2 hPRKCB/iso:Beta-II acts_upstream_of_or_withinGO:0001666 response to hypoxia MGI_ref:3847400; PMID:18323529
located_inGO:0016020 membrane MGI_ref:3847400; PMID:18323529