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Protein Ontology report - adenomatous polyposis coli protein (human)
PR:P25054 - http://purl.obolibrary.org/obo/PR_P25054
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:P25054   
  PRO nameadenomatous polyposis coli protein (human) 
  Synonyms
PRO-Short-label: EXACT:hAPC
Gene-based: RELATED:APC | DP2.5
Other: EXACT:deleted in polyposis 2.5 (human) | protein APC (human)
  Definition"An adenomatous polyposis coli protein that is encoded in the genome of human." [PMID:11283619, PMID:20823832, PRO:KER] 
  PRO Categoryorganism-gene 
  ParentPR:000004122 adenomatous polyposis coli protein
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:583 APC (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 81                                        
         Modification0                                                  Organism-Modification 16                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P25054
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P25054 adenomatous polyposis coli protein (human)
hAPC
Yes
Yes
organism-sequence


PR:000060341 adenomatous polyposis coli protein sequence variant Q1367* (human)
hAPC/var:Q1367*

organism-sequence


PR:000060552 adenomatous polyposis coli protein sequence variant R876* (human)
hAPC/var:R876*

organism-sequence


PR:000060651 adenomatous polyposis coli protein sequence variant E1379* (human)
hAPC/var:E1379*

organism-sequence


PR:000060672 adenomatous polyposis coli protein sequence variant R302* (human)
hAPC/var:R302*

organism-sequence


PR:000060849 adenomatous polyposis coli protein sequence variant S1315* (human)
hAPC/var:S1315*

organism-sequence


PR:000060863 adenomatous polyposis coli protein sequence variant E941* (human)
hAPC/var:E941*

organism-sequence


PR:000060917 adenomatous polyposis coli protein sequence variant Q1469* (human)
hAPC/var:Q1469*

organism-sequence


PR:000060972 adenomatous polyposis coli protein sequence variant S1539* (human)
hAPC/var:S1539*

organism-sequence


PR:000061011 adenomatous polyposis coli protein sequence variant G1288* (human)
hAPC/var:G1288*

organism-sequence


PR:000061056 adenomatous polyposis coli protein sequence variant R805* (human)
hAPC/var:R805*

organism-sequence


PR:000061099 adenomatous polyposis coli protein sequence variant Y935* (human)
hAPC/var:Y935*

organism-sequence


PR:000061158 adenomatous polyposis coli protein sequence variant S1344* (human)
hAPC/var:S1344*

organism-sequence


PR:000061192 adenomatous polyposis coli protein sequence variant L1564* (human)
hAPC/var:L1564*

organism-sequence


PR:000061287 adenomatous polyposis coli protein sequence variant E1577* (human)
hAPC/var:E1577*

organism-sequence


PR:000061394 adenomatous polyposis coli protein sequence variant S895* (human)
hAPC/var:S895*

organism-sequence


PR:000061450 adenomatous polyposis coli protein sequence variant E1573* (human)
hAPC/var:E1573*

organism-sequence


PR:000061495 adenomatous polyposis coli protein sequence variant Q1328* (human)
hAPC/var:Q1328*

organism-sequence


PR:000061514 adenomatous polyposis coli protein sequence variant K1308* (human)
hAPC/var:K1308*

organism-sequence


PR:000061560 adenomatous polyposis coli protein sequence variant K1310* (human)
hAPC/var:K1310*

organism-sequence


PR:000061672 adenomatous polyposis coli protein sequence variant E1451* (human)
hAPC/var:E1451*

organism-sequence


PR:000061689 adenomatous polyposis coli protein sequence variant S1282* (human)
hAPC/var:S1282*

organism-sequence


PR:000061783 adenomatous polyposis coli protein sequence variant S1356* (human)
hAPC/var:S1356*

organism-sequence


PR:000061802 adenomatous polyposis coli protein sequence variant E1151* (human)
hAPC/var:E1151*

organism-sequence


PR:000061808 adenomatous polyposis coli protein sequence variant E1408* (human)
hAPC/var:E1408*

organism-sequence


PR:000061823 adenomatous polyposis coli protein sequence variant E1374* (human)
hAPC/var:E1374*

organism-sequence


PR:000061902 adenomatous polyposis coli protein sequence variant C1410* (human)
hAPC/var:C1410*

organism-sequence


PR:000061951 adenomatous polyposis coli protein sequence variant L1488* (human)
hAPC/var:L1488*

organism-sequence


PR:000062004 adenomatous polyposis coli protein sequence variant R332* (human)
hAPC/var:R332*

organism-sequence


PR:000062035 adenomatous polyposis coli protein sequence variant E1309* (human)
hAPC/var:E1309*

organism-sequence


PR:000062080 adenomatous polyposis coli protein sequence variant E1536* (human)
hAPC/var:E1536*

organism-sequence


PR:000062099 adenomatous polyposis coli protein sequence variant E1464* (human)
hAPC/var:E1464*

organism-sequence


PR:000062100 adenomatous polyposis coli protein sequence variant S1327* (human)
hAPC/var:S1327*

organism-sequence


PR:000062160 adenomatous polyposis coli protein sequence variant E1397* (human)
hAPC/var:E1397*

organism-sequence


PR:000062179 adenomatous polyposis coli protein sequence variant S1400* (human)
hAPC/var:S1400*

organism-sequence


PR:000062257 adenomatous polyposis coli protein sequence variant R213* (human)
hAPC/var:R213*

organism-sequence


PR:000062325 adenomatous polyposis coli protein sequence variant R1450* (human)
hAPC/var:R1450*

organism-sequence


PR:000062382 adenomatous polyposis coli protein sequence variant S943* (human)
hAPC/var:S943*

organism-sequence


PR:000062413 adenomatous polyposis coli protein sequence variant G1412* (human)
hAPC/var:G1412*

organism-sequence


PR:000062430 adenomatous polyposis coli protein sequence variant E1353* (human)
hAPC/var:E1353*

organism-sequence


PR:000062505 adenomatous polyposis coli protein sequence variant R405* (human)
hAPC/var:R405*

organism-sequence


PR:000062522 adenomatous polyposis coli protein sequence variant R283* (human)
hAPC/var:R283*

organism-sequence


PR:000062533 adenomatous polyposis coli protein sequence variant Q767* (human)
hAPC/var:Q767*

organism-sequence


PR:000062567 adenomatous polyposis coli protein sequence variant E1544* (human)
hAPC/var:E1544*

organism-sequence


PR:000062652 adenomatous polyposis coli protein sequence variant S1346* (human)
hAPC/var:S1346*

organism-sequence


PR:000062666 adenomatous polyposis coli protein sequence variant F1197* (human)
hAPC/var:F1197*

organism-sequence


PR:000062797 adenomatous polyposis coli protein sequence variant E1322* (human)
hAPC/var:E1322*

organism-sequence


PR:000062813 adenomatous polyposis coli protein sequence variant S1392* (human)
hAPC/var:S1392*

organism-sequence


PR:000062815 adenomatous polyposis coli protein sequence variant E1306* (human)
hAPC/var:E1306*

organism-sequence


PR:000062875 adenomatous polyposis coli protein sequence variant Y1376* (human)
hAPC/var:Y1376*

organism-sequence


PR:000062879 adenomatous polyposis coli protein sequence variant G1312* (human)
hAPC/var:G1312*

organism-sequence


PR:000062917 adenomatous polyposis coli protein sequence variant R564* (human)
hAPC/var:R564*

organism-sequence


PR:000062949 adenomatous polyposis coli protein sequence variant E1284* (human)
hAPC/var:E1284*

organism-sequence


PR:000062974 adenomatous polyposis coli protein sequence variant R1386* (human)
hAPC/var:R1386*

organism-sequence


PR:000063233 adenomatous polyposis coli protein sequence variant K1363* (human)
hAPC/var:K1363*

organism-sequence


PR:000063261 adenomatous polyposis coli protein sequence variant S1281* (human)
hAPC/var:S1281*

organism-sequence


PR:000063263 adenomatous polyposis coli protein sequence variant Q886* (human)
hAPC/var:Q886*

organism-sequence


PR:000063548 adenomatous polyposis coli protein sequence variant Q1303* (human)
hAPC/var:Q1303*

organism-sequence


PR:000063804 adenomatous polyposis coli protein sequence variant Q1127* (human)
hAPC/var:Q1127*

organism-sequence


PR:000063808 adenomatous polyposis coli protein sequence variant Q1378* (human)
hAPC/var:Q1378*

organism-sequence


PR:000063820 adenomatous polyposis coli protein sequence variant R1114* (human)
hAPC/var:R1114*

organism-sequence


PR:000063956 adenomatous polyposis coli protein sequence variant W1049* (human)
hAPC/var:W1049*

organism-sequence


PR:000063965 adenomatous polyposis coli protein sequence variant E1554* (human)
hAPC/var:E1554*

organism-sequence


PR:000063968 adenomatous polyposis coli protein sequence variant E1209* (human)
hAPC/var:E1209*

organism-sequence


PR:000064061 adenomatous polyposis coli protein sequence variant K993* (human)
hAPC/var:K993*

organism-sequence


PR:000064078 adenomatous polyposis coli protein sequence variant R554* (human)
hAPC/var:R554*

organism-sequence


PR:000064116 adenomatous polyposis coli protein sequence variant R499* (human)
hAPC/var:R499*

organism-sequence


PR:000064179 adenomatous polyposis coli protein sequence variant E1286* (human)
hAPC/var:E1286*

organism-sequence


PR:000064266 adenomatous polyposis coli protein sequence variant E984* (human)
hAPC/var:E984*

organism-sequence


PR:000064268 adenomatous polyposis coli protein sequence variant Q1429* (human)
hAPC/var:Q1429*

organism-sequence


PR:000064291 adenomatous polyposis coli protein sequence variant R232* (human)
hAPC/var:R232*

organism-sequence


PR:000064330 adenomatous polyposis coli protein sequence variant G1357* (human)
hAPC/var:G1357*

organism-sequence


PR:000064362 adenomatous polyposis coli protein sequence variant Q1294* (human)
hAPC/var:Q1294*

organism-sequence


PR:000064434 adenomatous polyposis coli protein sequence variant E1295* (human)
hAPC/var:E1295*

organism-sequence


PR:000064469 adenomatous polyposis coli protein sequence variant Q1406* (human)
hAPC/var:Q1406*

organism-sequence


PR:000064474 adenomatous polyposis coli protein sequence variant E1345* (human)
hAPC/var:E1345*

organism-sequence


PR:000064598 adenomatous polyposis coli protein sequence variant Q1338* (human)
hAPC/var:Q1338*

organism-sequence


PR:000064608 adenomatous polyposis coli protein sequence variant S811* (human)
hAPC/var:S811*

organism-sequence


PR:000064613 adenomatous polyposis coli protein sequence variant E1317* (human)
hAPC/var:E1317*

organism-sequence


PR:P25054-1 adenomatous polyposis coli protein isoform h1A (human)
hAPC/iso:h1A

organism-modification


PR:000061214 adenomatous polyposis coli protein isoform h1A phosphorylated 1 (human)
hAPC/iso:h1A/Phos:1

organism-modification


PR:000061281 adenomatous polyposis coli protein isoform h1A phosphorylated 2 (human)
hAPC/iso:h1A/Phos:2

organism-modification


PR:000061579 adenomatous polyposis coli protein isoform h1A phosphorylated 3 (human)
hAPC/iso:h1A/Phos:3

organism-modification


PR:000061596 adenomatous polyposis coli protein isoform h1A phosphorylated 4 (human)
hAPC/iso:h1A/Phos:4

organism-sequence


PR:P25054-2 adenomatous polyposis coli protein isoform h2 (human)
hAPC/iso:h2

organism-sequence


PR:P25054-3 adenomatous polyposis coli protein isoform h1B (human)
hAPC/iso:h1B

organism-modification


PR:000030183 adenomatous polyposis coli protein phosphorylated 1 (human)
hAPC/Phos:1

organism-modification


PR:000030185 adenomatous polyposis coli protein phosphorylated 2 (human)
hAPC/Phos:2

organism-modification


PR:000030187 adenomatous polyposis coli protein phosphorylated 3 (human)
hAPC/Phos:3

organism-modification


PR:000030189 adenomatous polyposis coli protein phosphorylated 4 (human)
hAPC/Phos:4

organism-modification


PR:000046350 adenomatous polyposis coli protein phosphorylated and ubiquitinated form (human)
hAPC/PhosUbiq+

organism-modification


PR:000046351 adenomatous polyposis coli protein ubiquitinated form (human)
hAPC/UbiqLys+

organism-modification


PR:000046350 adenomatous polyposis coli protein phosphorylated and ubiquitinated form (human)
hAPC/PhosUbiq+

organism-modification


PR:000056237 adenomatous polyposis coli protein N-glycosylated 1 (human)
hAPC/NGlyco:1

organism-modification


PR:000068028 adenomatous polyposis coli protein cysteinylated 1 (human)
hAPC/Cyst:1

organism-modification


PR:000070520 adenomatous polyposis coli protein methylated 1 (human)
hAPC/Me:1

organism-modification


PR:000073364 adenomatous polyposis coli protein phosphorylated 5 (human)
hAPC/Phos:5

organism-modification


PR:000077353 adenomatous polyposis coli protein cysteinylated 2 (human)
hAPC/Cyst:2

organism-modification


PR:000085314 adenomatous polyposis coli protein methylated 2 (human)
hAPC/Me:2

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hAPC forms found in complexes   

hAPC Component
 Complexes
PR:P25054 hAPC PR:000035576 BUB1:BUB3:APC complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P25054 hAPC acts_upstream_of_or_withinGO:0007059 chromosome segregation PMID:11283619
NOT GO:0031577 spindle checkpoint signaling PMID:11283619
enablesGO:0005515 protein binding with PR:O14641 dishevelled-2 (human) BioGRID:BG-302957
GO:0005515 protein binding with PR:O43683 BUB1 BioGRID:BG-302957
GO:0005515 protein binding with PR:O43684 BUB3 BioGRID:BG-302957
GO:0005515 protein binding with PR:Q13257 hMAD2L1 BioGRID:BG-302957
GO:0008017 microtubule binding PMID:11283619
located_inGO:0000776 kinetochore PMID:11283619