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Protein Ontology report - bone morphogenetic protein
PR:000000034 - http://purl.obolibrary.org/obo/PR_000000034
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000034   
  PRO namebone morphogenetic protein 
  Definition"A TGF-beta-like cystine-knot cytokine that is related to the transforming growth factor-beta, anti-Muellerian hormone, and activin/inhibin protein families, which are all involved in the regulation of cell growth and differentiation. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release bioactive the C-terminal peptide. BMP is involved in body patterning and morphogenesis. BMP signals are transmitted through specific type 2 and type 1 receptors." [PIRSF:PIRSF037272
  PRO Categoryfamily 
  ParentPR:000000008 TGF-beta-like cystine-knot cytokine
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene12                                                  Organism-Gene 34                                        
         Sequence8                                                  Organism-Sequence 21                                        
         Modification18                                                  Organism-Modification 22                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF037272
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000000034

bone morphogenetic protein

fam:CBP-p300


"A TGF-beta-like cystine-knot cytokine that is related to the transforming growth factor-beta, anti-Muellerian hormone, and activin/inhibin protein families, which are all involved in the regulation of cell growth and differentiation. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release bioactive the C-terminal peptide. BMP is involved in body patterning and morphogenesis. BMP signals are transmitted through specific type 2 and type 1 receptors." [PIRSF:PIRSF037272]

Yes

gene



PR:000000163

bone morphogenetic protein 10

BMP10


"A bone morphogenetic protein that is a translation product of the human BMP10 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:G5EEL5

protein dbl-1 (worm)

BMP10 (worm)


"A bone morphogenetic protein 10 that is encoded in the genome of worm." [OMA:G5EEL5, PRO:DNx]


organism-gene



PR:O95393

bone morphogenetic protein 10 (human)

hBMP10


"A bone morphogenetic protein 10 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O95393]


organism-sequence



PR:O95393-1

bone morphogenetic protein 10 isoform 1 (human)

hBMP10/iso:1


"A bone morphogenetic protein 10 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000046490

bone morphogenetic protein 10, signal peptide removed form (human)

hBMP10/SigPep-


"A bone morphogenetic protein 10 (human) that has had the signal peptide removed. UniProtKB:O95393, 22-424." [PRO:DNx, Reactome:R-HSA-2396409]


organism-modification



PR:000067108

bone morphogenetic protein 10, mature form (human)

hBMP10/mature


"A bone morphogenetic protein 10 (human) that has had the signal peptide and propeptide removed. UniProtKB:O95393, 317-424." [PRO:DNx, Reactome:R-HSA-8858374]


organism-modification



PR:000067108

bone morphogenetic protein 10, mature form (human)

hBMP10/mature


"A bone morphogenetic protein 10 (human) that has had the signal peptide and propeptide removed. UniProtKB:O95393, 317-424." [PRO:DNx, Reactome:R-HSA-8858374]


organism-gene



PR:Q4AEG6

bone morphogenetic protein 10 (rat)

rBMP10


"A bone morphogenetic protein 10 that is encoded in the genome of rat." [OMA:Q4AEG6, PRO:DNx]


organism-gene



PR:Q9R229

bone morphogenetic protein 10 (mouse)

mBMP10


"A bone morphogenetic protein 10 that is encoded in the genome of mouse." [OMA:Q9R229, PRO:DNx]


organism-sequence



PR:Q9R229-1

bone morphogenetic protein 10 isoform 1 (mouse)

mBMP10/iso:1


"A bone morphogenetic protein 10 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

sequence



PR:000000384

bone morphogenetic protein 10 isoform 1

BMP10/iso:1


"A bone morphogenetic protein 10 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95393-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:O95393-1

bone morphogenetic protein 10 isoform 1 (human)

hBMP10/iso:1


"A bone morphogenetic protein 10 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q9R229-1

bone morphogenetic protein 10 isoform 1 (mouse)

mBMP10/iso:1


"A bone morphogenetic protein 10 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

gene



PR:000000164

bone morphogenetic protein 2

BMP2


"A bone morphogenetic protein that is a translation product of the human BMP2 gene or a 1:1 ortholog thereof." [PRO:CNA]

Yes

organism-gene



PR:P12643

bone morphogenetic protein 2 (human)

hBMP2


"A bone morphogenetic protein 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P12643]


organism-sequence



PR:P12643-1

bone morphogenetic protein 2 isoform 1 (human)

hBMP2/iso:1


"A bone morphogenetic protein 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000026336

bone morphogenetic protein 2 isoform 1, mature form (human)

hBMP2/iso:1/mature


"A bone morphogenetic protein 2 isoform 1, mature form in human. UniProtKB:P12643-1, 283-396." [PRO:DNx, UniProtKB:P12643]

Yes

organism-modification



PR:000046491

bone morphogenetic protein 2, signal peptide removed form (human)

hBMP2/SigPep-


"A bone morphogenetic protein 2 (human) that has had the signal peptide removed. UniProtKB:P12643, 24-396." [PRO:DNx, Reactome:R-HSA-2396130]


organism-modification



PR:000026336

bone morphogenetic protein 2 isoform 1, mature form (human)

hBMP2/iso:1/mature


"A bone morphogenetic protein 2 isoform 1, mature form in human. UniProtKB:P12643-1, 283-396." [PRO:DNx, UniProtKB:P12643]

Yes

organism-gene



PR:P21274

bone morphogenetic protein 2 (mouse)

mBMP2


"A bone morphogenetic protein 2 that is encoded in the genome of mouse." [OMA:P21274, PRO:DNx]


organism-sequence



PR:000050190

bone morphogenetic protein 2 isoform m2 (mouse)

mBMP2/iso:m2


"A bone morphogenetic protein 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P21274-1, 59-394. This isoform is encoded from an alternative downstream start codon relative to that encoding for isoform 1. UniProtKB:P21274-1, 59-394." [PMID:20230640, PMID:30700748, PRO:HJD]


organism-sequence



PR:P21274-1

bone morphogenetic protein 2 isoform 1 (mouse)

mBMP2/iso:1


"A bone morphogenetic protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036510

bone morphogenetic protein 2 isoform 1, mature form (mouse)

mBMP2/iso:1/mature


"A bone morphogenetic protein 2 isoform 1, mature form in mouse. UniProtKB:P21274-1, 281-394." [PMID:14623234, PMID:15110716, PMID:15565649, PMID:16109715, PRO:CNA]

Yes

organism-gene



PR:P49001

bone morphogenetic protein 2 (rat)

rBMP2


"A bone morphogenetic protein 2 that is encoded in the genome of rat." [OMA:P49001, PRO:DNx]


sequence



PR:000000385

bone morphogenetic protein 2 isoform 1

BMP2/iso:1


"A bone morphogenetic protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12643-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P12643-1

bone morphogenetic protein 2 isoform 1 (human)

hBMP2/iso:1


"A bone morphogenetic protein 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000026336

bone morphogenetic protein 2 isoform 1, mature form (human)

hBMP2/iso:1/mature


"A bone morphogenetic protein 2 isoform 1, mature form in human. UniProtKB:P12643-1, 283-396." [PRO:DNx, UniProtKB:P12643]

Yes

organism-sequence



PR:P21274-1

bone morphogenetic protein 2 isoform 1 (mouse)

mBMP2/iso:1


"A bone morphogenetic protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036510

bone morphogenetic protein 2 isoform 1, mature form (mouse)

mBMP2/iso:1/mature


"A bone morphogenetic protein 2 isoform 1, mature form in mouse. UniProtKB:P21274-1, 281-394." [PMID:14623234, PMID:15110716, PMID:15565649, PMID:16109715, PRO:CNA]

Yes

modification



PR:000000608

bone morphogenetic protein 2 isoform 1, mature form

BMP2/iso:1/mature


"A bone morphogenetic protein 2 isoform 1 that has had the signal peptide and propeptide removed." [PMID:10074410]


organism-modification



PR:000026336

bone morphogenetic protein 2 isoform 1, mature form (human)

hBMP2/iso:1/mature


"A bone morphogenetic protein 2 isoform 1, mature form in human. UniProtKB:P12643-1, 283-396." [PRO:DNx, UniProtKB:P12643]

Yes

organism-modification



PR:000036510

bone morphogenetic protein 2 isoform 1, mature form (mouse)

mBMP2/iso:1/mature


"A bone morphogenetic protein 2 isoform 1, mature form in mouse. UniProtKB:P21274-1, 281-394." [PMID:14623234, PMID:15110716, PMID:15565649, PMID:16109715, PRO:CNA]

Yes

modification



PR:000021898

bone morphogenetic protein 2 isoform 1, signal peptide removed form

BMP2/iso:1/SigPep-


"A bone morphogenetic protein 2 isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000608

bone morphogenetic protein 2 isoform 1, mature form

BMP2/iso:1/mature


"A bone morphogenetic protein 2 isoform 1 that has had the signal peptide and propeptide removed." [PMID:10074410]


organism-modification



PR:000026336

bone morphogenetic protein 2 isoform 1, mature form (human)

hBMP2/iso:1/mature


"A bone morphogenetic protein 2 isoform 1, mature form in human. UniProtKB:P12643-1, 283-396." [PRO:DNx, UniProtKB:P12643]

Yes

organism-modification



PR:000036510

bone morphogenetic protein 2 isoform 1, mature form (mouse)

mBMP2/iso:1/mature


"A bone morphogenetic protein 2 isoform 1, mature form in mouse. UniProtKB:P21274-1, 281-394." [PMID:14623234, PMID:15110716, PMID:15565649, PMID:16109715, PRO:CNA]

Yes

modification



PR:000018286

bone morphogenetic protein 2 proteolytic cleavage product

BMP2/ClvPrd


"A bone morphogenetic protein 2 that has been processed by proteolytic cleavage." [PRO:DNx]


gene



PR:000000165

bone morphogenetic protein 4

BMP4


"A bone morphogenetic protein that is a translation product of the human BMP4 gene or a 1:1 ortholog thereof." [PRO:CNA]

Yes

organism-gene



PR:P12644

bone morphogenetic protein 4 (human)

hBMP4


"A bone morphogenetic protein 4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P12644]


organism-sequence



PR:P12644-1

bone morphogenetic protein 4 isoform 1 (human)

hBMP4/iso:1


"A bone morphogenetic protein 4 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036511

bone morphogenetic protein 4 isoform 1, mature form (human)

hBMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1, mature form in human. UniProtKB:P12644-1, 293-408." [PMID:11401399, PMID:12141440, PMID:12805376, PMID:14660436, PMID:14749725, PMID:9804553, PRO:CNA]

Yes

organism-modification



PR:000046492

bone morphogenetic protein 4, signal peptide removed form (human)

hBMP4/SigPep-


"A bone morphogenetic protein 4 (human) that has had the signal peptide removed. UniProtKB:P12644, 20-408." [PRO:DNx, Reactome:R-HSA-2396280]


organism-modification



PR:000072771

bone morphogenetic protein 4, mature form (human)

hBMP4/mature


"A bone morphogenetic protein 4 (human) that has had the signal peptide and propeptide removed. UniProtKB:P12644, 293-408." [PRO:DNx, Reactome:R-HSA-8858573, Reactome:R-HSA-8956775]


organism-modification



PR:000036511

bone morphogenetic protein 4 isoform 1, mature form (human)

hBMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1, mature form in human. UniProtKB:P12644-1, 293-408." [PMID:11401399, PMID:12141440, PMID:12805376, PMID:14660436, PMID:14749725, PMID:9804553, PRO:CNA]

Yes

organism-modification



PR:000072824

bone morphogenetic protein 4, mature phosphorylated form (human)

hBMP4/mature/PhosRes+


"A bone morphogenetic protein 4 (human) that has had the signal peptide and propeptide removed, and that includes at least one phosphorylated residue. UniProtKB:P12644, 293-408, MOD:00696." [PRO:DNx, Reactome:R-HSA-8956944]


organism-modification



PR:000072771

bone morphogenetic protein 4, mature form (human)

hBMP4/mature


"A bone morphogenetic protein 4 (human) that has had the signal peptide and propeptide removed. UniProtKB:P12644, 293-408." [PRO:DNx, Reactome:R-HSA-8858573, Reactome:R-HSA-8956775]


organism-modification



PR:000036511

bone morphogenetic protein 4 isoform 1, mature form (human)

hBMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1, mature form in human. UniProtKB:P12644-1, 293-408." [PMID:11401399, PMID:12141440, PMID:12805376, PMID:14660436, PMID:14749725, PMID:9804553, PRO:CNA]

Yes

organism-modification



PR:000072824

bone morphogenetic protein 4, mature phosphorylated form (human)

hBMP4/mature/PhosRes+


"A bone morphogenetic protein 4 (human) that has had the signal peptide and propeptide removed, and that includes at least one phosphorylated residue. UniProtKB:P12644, 293-408, MOD:00696." [PRO:DNx, Reactome:R-HSA-8956944]


organism-modification



PR:000072824

bone morphogenetic protein 4, mature phosphorylated form (human)

hBMP4/mature/PhosRes+


"A bone morphogenetic protein 4 (human) that has had the signal peptide and propeptide removed, and that includes at least one phosphorylated residue. UniProtKB:P12644, 293-408, MOD:00696." [PRO:DNx, Reactome:R-HSA-8956944]


organism-gene



PR:P21275

bone morphogenetic protein 4 (mouse)

mBMP4


"A bone morphogenetic protein 4 that is encoded in the genome of mouse." [OMA:P21275, PRO:DNx]

Yes

organism-sequence



PR:000050192

bone morphogenetic protein 4 isoform m2 (mouse)

mBMP4/iso:m2


"A bone morphogenetic protein 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:PR:P21275-1, 83-408. This isoform is encoded from an alternative downstream start codon relative to that encoding for isoform 1." [PMID:20230640, PRO:HJD]


organism-sequence



PR:P21275-1

bone morphogenetic protein 4 isoform 1 (mouse)

mBMP4/iso:1


"A bone morphogenetic protein 4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-modification



PR:000036512

bone morphogenetic protein 4 isoform 1, mature form (mouse)

mBMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1, mature form in mouse. UniProtKB:P21275-1, 293-408." [PMID:12631064, PMID:14623234, PMID:15381701, PRO:CNA]

Yes

organism-gene



PR:Q06826

bone morphogenetic protein 4 (rat)

rBMP4


"A bone morphogenetic protein 4 that is encoded in the genome of rat." [OMA:Q06826, PRO:DNx]


sequence



PR:000000386

bone morphogenetic protein 4 isoform 1

BMP4/iso:1


"A bone morphogenetic protein 4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12644-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P12644-1

bone morphogenetic protein 4 isoform 1 (human)

hBMP4/iso:1


"A bone morphogenetic protein 4 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036511

bone morphogenetic protein 4 isoform 1, mature form (human)

hBMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1, mature form in human. UniProtKB:P12644-1, 293-408." [PMID:11401399, PMID:12141440, PMID:12805376, PMID:14660436, PMID:14749725, PMID:9804553, PRO:CNA]

Yes

organism-sequence



PR:P21275-1

bone morphogenetic protein 4 isoform 1 (mouse)

mBMP4/iso:1


"A bone morphogenetic protein 4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-modification



PR:000036512

bone morphogenetic protein 4 isoform 1, mature form (mouse)

mBMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1, mature form in mouse. UniProtKB:P21275-1, 293-408." [PMID:12631064, PMID:14623234, PMID:15381701, PRO:CNA]

Yes

modification



PR:000000609

bone morphogenetic protein 4 isoform 1, mature form

BMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1 that has had the signal peptide and propeptide removed." [PMID:12805376]


organism-modification



PR:000036511

bone morphogenetic protein 4 isoform 1, mature form (human)

hBMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1, mature form in human. UniProtKB:P12644-1, 293-408." [PMID:11401399, PMID:12141440, PMID:12805376, PMID:14660436, PMID:14749725, PMID:9804553, PRO:CNA]

Yes

organism-modification



PR:000036512

bone morphogenetic protein 4 isoform 1, mature form (mouse)

mBMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1, mature form in mouse. UniProtKB:P21275-1, 293-408." [PMID:12631064, PMID:14623234, PMID:15381701, PRO:CNA]

Yes

modification



PR:000021899

bone morphogenetic protein 4 isoform 1, signal peptide removed form

BMP4/iso:1/SigPep-


"A bone morphogenetic protein 4 isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000609

bone morphogenetic protein 4 isoform 1, mature form

BMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1 that has had the signal peptide and propeptide removed." [PMID:12805376]


organism-modification



PR:000036511

bone morphogenetic protein 4 isoform 1, mature form (human)

hBMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1, mature form in human. UniProtKB:P12644-1, 293-408." [PMID:11401399, PMID:12141440, PMID:12805376, PMID:14660436, PMID:14749725, PMID:9804553, PRO:CNA]

Yes

organism-modification



PR:000036512

bone morphogenetic protein 4 isoform 1, mature form (mouse)

mBMP4/iso:1/mature


"A bone morphogenetic protein 4 isoform 1, mature form in mouse. UniProtKB:P21275-1, 293-408." [PMID:12631064, PMID:14623234, PMID:15381701, PRO:CNA]

Yes

modification



PR:000018287

bone morphogenetic protein 4 proteolytic cleavage product

BMP4/ClvPrd


"A bone morphogenetic protein 4 that has been processed by proteolytic cleavage." [PRO:DNx]


gene



PR:000000166

bone morphogenetic protein 5

BMP5


"A bone morphogenetic protein that is a translation product of the human BMP5 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P22003

bone morphogenetic protein 5 (human)

hBMP5


"A bone morphogenetic protein 5 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P22003]


organism-sequence



PR:P22003-1

bone morphogenetic protein 5 isoform 1 (human)

hBMP5/iso:1


"A bone morphogenetic protein 5 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036513

bone morphogenetic protein 5 isoform 1, mature form (human)

hBMP5/iso:1/mature


"A bone morphogenetic protein 5 isoform 1, mature form in human. UniProtKB:P22003-1, 323-454." [PMID:11401399, PMID:14660436, PRO:CNA]

Yes

organism-sequence



PR:P22003-2

bone morphogenetic protein 5 isoform h2 (human)

hBMP5/iso:h2


"A bone morphogenetic protein 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22003-2." [PRO:DNx, UniProtKB:P22003]


organism-gene



PR:P49003

bone morphogenetic protein 5 (mouse)

mBMP5


"A bone morphogenetic protein 5 that is encoded in the genome of mouse." [OMA:P49003, PRO:DNx]

Yes

organism-sequence



PR:P49003-1

bone morphogenetic protein 5 isoform m1 (mouse)

mBMP5/iso:m1


"A bone morphogenetic protein 5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49003-1." [PRO:DNx, UniProtKB:P49003]


organism-sequence



PR:P49003-2

bone morphogenetic protein 5 isoform 2 (mouse)

mBMP5/iso:2


"A bone morphogenetic protein 5 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


sequence



PR:000000387

bone morphogenetic protein 5 isoform 1

BMP5/iso:1


"A bone morphogenetic protein 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22003-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P22003-1

bone morphogenetic protein 5 isoform 1 (human)

hBMP5/iso:1


"A bone morphogenetic protein 5 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036513

bone morphogenetic protein 5 isoform 1, mature form (human)

hBMP5/iso:1/mature


"A bone morphogenetic protein 5 isoform 1, mature form in human. UniProtKB:P22003-1, 323-454." [PMID:11401399, PMID:14660436, PRO:CNA]

Yes

organism-sequence



PR:P49003-2

bone morphogenetic protein 5 isoform 2 (mouse)

mBMP5/iso:2


"A bone morphogenetic protein 5 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


modification



PR:000000610

bone morphogenetic protein 5 isoform 1, mature form

BMP5/iso:1/mature


"A bone morphogenetic protein 5 isoform 1 that has had the signal peptide and propeptide removed." [PRO:CNA, PRO:DAN]


organism-modification



PR:000036513

bone morphogenetic protein 5 isoform 1, mature form (human)

hBMP5/iso:1/mature


"A bone morphogenetic protein 5 isoform 1, mature form in human. UniProtKB:P22003-1, 323-454." [PMID:11401399, PMID:14660436, PRO:CNA]

Yes

modification



PR:000021900

bone morphogenetic protein 5 isoform 1, signal peptide removed form

BMP5/iso:1/SigPep-


"A bone morphogenetic protein 5 isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000610

bone morphogenetic protein 5 isoform 1, mature form

BMP5/iso:1/mature


"A bone morphogenetic protein 5 isoform 1 that has had the signal peptide and propeptide removed." [PRO:CNA, PRO:DAN]


organism-modification



PR:000036513

bone morphogenetic protein 5 isoform 1, mature form (human)

hBMP5/iso:1/mature


"A bone morphogenetic protein 5 isoform 1, mature form in human. UniProtKB:P22003-1, 323-454." [PMID:11401399, PMID:14660436, PRO:CNA]

Yes

modification



PR:000021931

bone morphogenetic protein 5 proteolytic cleavage product

BMP5/ClvPrd


"A bone morphogenetic protein 5 that has been processed by proteolytic cleavage." [PRO:DAN]


gene



PR:000000167

bone morphogenetic protein 6

BMP6


"A bone morphogenetic protein that is a translation product of the human BMP6 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P20722

bone morphogenetic protein 6 (mouse)

mBMP6


"A bone morphogenetic protein 6 that is encoded in the genome of mouse." [OMA:P20722, PRO:DNx]


organism-sequence



PR:P20722-1

bone morphogenetic protein 6 isoform 1 (mouse)

mBMP6/iso:1


"A bone morphogenetic protein 6 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036515

bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse)

mBMP6/iso:1/ClvNGlyco:1


"A bone morphogenetic protein 6 isoform 1, mature form in mouse that has been N-glycosylated at Asn-451 of the amino acid sequence represented by UniProtKB:P20722-1. UniProtKB:P20722-1, 372-510, Asn-451, MOD:00160." [PMID:14623234, PMID:8089189, PRO:CNA, PRO:DAN]

Yes

organism-gene



PR:P22004

bone morphogenetic protein 6 (human)

hBMP6


"A bone morphogenetic protein 6 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P22004]


organism-sequence



PR:P22004-1

bone morphogenetic protein 6 isoform 1 (human)

hBMP6/iso:1


"A bone morphogenetic protein 6 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036514

bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human)

hBMP6/iso:1/ClvNGlyco:1


"A bone morphogenetic protein 6 isoform 1, mature form in human that has been N-glycosylated at Asn-454 of the amino acid sequence represented by UniProtKB:P22004-1. UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160." [PMID:12702725, PMID:15969083, PMID:16527843, PMID:18070108, PRO:CNA, PRO:DAN]

Yes

organism-gene



PR:Q04906

bone morphogenetic protein 6 (rat)

rBMP6


"A bone morphogenetic protein 6 that is encoded in the genome of rat." [OMA:Q04906, PRO:DNx]


sequence



PR:000000388

bone morphogenetic protein 6 isoform 1

BMP6/iso:1


"A bone morphogenetic protein 6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22004-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P20722-1

bone morphogenetic protein 6 isoform 1 (mouse)

mBMP6/iso:1


"A bone morphogenetic protein 6 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036515

bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse)

mBMP6/iso:1/ClvNGlyco:1


"A bone morphogenetic protein 6 isoform 1, mature form in mouse that has been N-glycosylated at Asn-451 of the amino acid sequence represented by UniProtKB:P20722-1. UniProtKB:P20722-1, 372-510, Asn-451, MOD:00160." [PMID:14623234, PMID:8089189, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:P22004-1

bone morphogenetic protein 6 isoform 1 (human)

hBMP6/iso:1


"A bone morphogenetic protein 6 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036514

bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human)

hBMP6/iso:1/ClvNGlyco:1


"A bone morphogenetic protein 6 isoform 1, mature form in human that has been N-glycosylated at Asn-454 of the amino acid sequence represented by UniProtKB:P22004-1. UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160." [PMID:12702725, PMID:15969083, PMID:16527843, PMID:18070108, PRO:CNA, PRO:DAN]

Yes

modification



PR:000000611

bone morphogenetic protein 6 isoform 1, mature form

BMP6/iso:1/mature


"A bone morphogenetic protein 6 isoform 1 that has had the signal peptide and propeptide removed." [PMID:15969083]


organism-modification



PR:000036514

bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human)

hBMP6/iso:1/ClvNGlyco:1


"A bone morphogenetic protein 6 isoform 1, mature form in human that has been N-glycosylated at Asn-454 of the amino acid sequence represented by UniProtKB:P22004-1. UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160." [PMID:12702725, PMID:15969083, PMID:16527843, PMID:18070108, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036515

bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse)

mBMP6/iso:1/ClvNGlyco:1


"A bone morphogenetic protein 6 isoform 1, mature form in mouse that has been N-glycosylated at Asn-451 of the amino acid sequence represented by UniProtKB:P20722-1. UniProtKB:P20722-1, 372-510, Asn-451, MOD:00160." [PMID:14623234, PMID:8089189, PRO:CNA, PRO:DAN]

Yes

modification



PR:000021901

bone morphogenetic protein 6 isoform 1, signal peptide removed form

BMP6/iso:1/SigPep-


"A bone morphogenetic protein 6 isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000611

bone morphogenetic protein 6 isoform 1, mature form

BMP6/iso:1/mature


"A bone morphogenetic protein 6 isoform 1 that has had the signal peptide and propeptide removed." [PMID:15969083]


organism-modification



PR:000036514

bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (human)

hBMP6/iso:1/ClvNGlyco:1


"A bone morphogenetic protein 6 isoform 1, mature form in human that has been N-glycosylated at Asn-454 of the amino acid sequence represented by UniProtKB:P22004-1. UniProtKB:P22004-1, 375-513, Asn-454, MOD:00160." [PMID:12702725, PMID:15969083, PMID:16527843, PMID:18070108, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036515

bone morphogenetic protein 6 isoform 1 cleaved and N-glycosylated 1 (mouse)

mBMP6/iso:1/ClvNGlyco:1


"A bone morphogenetic protein 6 isoform 1, mature form in mouse that has been N-glycosylated at Asn-451 of the amino acid sequence represented by UniProtKB:P20722-1. UniProtKB:P20722-1, 372-510, Asn-451, MOD:00160." [PMID:14623234, PMID:8089189, PRO:CNA, PRO:DAN]

Yes

modification



PR:000021932

bone morphogenetic protein 6 proteolytic cleavage product

BMP6/ClvPrd


"A bone morphogenetic protein 6 that has been processed by proteolytic cleavage." [PRO:DAN]


gene



PR:000000168

bone morphogenetic protein 7

BMP7


"A bone morphogenetic protein that is a translation product of the human BMP7 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P18075

bone morphogenetic protein 7 (human)

hBMP7


"A bone morphogenetic protein 7 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P18075]


organism-sequence



PR:P18075-1

bone morphogenetic protein 7 isoform 1 (human)

hBMP7/iso:1


"A bone morphogenetic protein 7 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036517

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human)

hBMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in human. UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15047707, PMID:15929982, PMID:8570652, PMID:9872992, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036519

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human)

hBMP7/iso:1/mature/NGlyco:2


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000073618

bone morphogenetic protein 7, mature form (human)

hBMP7/mature


"A bone morphogenetic protein 7 (human) that has had the signal peptide and propeptide removed. UniProtKB:P18075, 293-431." [PRO:DNx, Reactome:R-HSA-206257]


organism-modification



PR:000036517

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human)

hBMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in human. UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15047707, PMID:15929982, PMID:8570652, PMID:9872992, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036519

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human)

hBMP7/iso:1/mature/NGlyco:2


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]

Yes

organism-gene



PR:P23359

bone morphogenetic protein 7 (mouse)

mBMP7


"A bone morphogenetic protein 7 that is encoded in the genome of mouse." [OMA:P23359, PRO:DNx]

Yes

organism-sequence



PR:P23359-1

bone morphogenetic protein 7 isoform 1 (mouse)

mBMP7/iso:1


"A bone morphogenetic protein 7 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036516

bone morphogenetic protein 7 isoform 1, mature form (mouse)

mBMP7/iso:1/mature


"A bone morphogenetic protein 7 isoform 1, mature form in mouse. UniProtKB:P23359-1, 292-430." [PMID:12741987, PRO:CNA]

Yes

organism-modification



PR:000036518

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)

mBMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in mouse. UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160." [PMID:14623234, PRO:CNA, PRO:DAN]

Yes

sequence



PR:000000389

bone morphogenetic protein 7 isoform 1

BMP7/iso:1


"A bone morphogenetic protein 7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18075-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P18075-1

bone morphogenetic protein 7 isoform 1 (human)

hBMP7/iso:1


"A bone morphogenetic protein 7 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036517

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human)

hBMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in human. UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15047707, PMID:15929982, PMID:8570652, PMID:9872992, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036519

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human)

hBMP7/iso:1/mature/NGlyco:2


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:P23359-1

bone morphogenetic protein 7 isoform 1 (mouse)

mBMP7/iso:1


"A bone morphogenetic protein 7 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000036516

bone morphogenetic protein 7 isoform 1, mature form (mouse)

mBMP7/iso:1/mature


"A bone morphogenetic protein 7 isoform 1, mature form in mouse. UniProtKB:P23359-1, 292-430." [PMID:12741987, PRO:CNA]

Yes

organism-modification



PR:000036518

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)

mBMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in mouse. UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160." [PMID:14623234, PRO:CNA, PRO:DAN]

Yes

modification



PR:000000612

bone morphogenetic protein 7 isoform 1, mature form

BMP7/iso:1/mature


"A bone morphogenetic protein 7 isoform 1 that has had the signal peptide and propeptide removed. Example: UniProtKB:P23359-1, 292-430." [PRO:CNA, PRO:DAN]


modification



PR:000000505

bone morphogenetic protein 7 isoform 1, mature glycosylated form

BMP7/iso:1/ClvGlyco+


"A bone morphogenetic protein 7 isoform 1, mature form that includes at least one glycosylated residue." [PRO:CNA, PRO:DAN]


modification



PR:000000613

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1

BMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature glycosylated form that is N-glycosylated at the N{P}[ST]{P} motif. This form is a disulfide linked homodimer. Example: UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]


organism-modification



PR:000036517

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human)

hBMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in human. UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15047707, PMID:15929982, PMID:8570652, PMID:9872992, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036518

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)

mBMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in mouse. UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160." [PMID:14623234, PRO:CNA, PRO:DAN]

Yes

modification



PR:000000614

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2

BMP7/iso:1/mature/NGlyco:2


"A bone morphogenetic protein 7 isoform 1, mature glycosylated form that has the propeptide still bound to the mature protein. This form is N-glycosylated at the most C-terminal N{P}[ST]{P} motif and is a homodimer. Example: UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982]


organism-modification



PR:000036519

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human)

hBMP7/iso:1/mature/NGlyco:2


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036516

bone morphogenetic protein 7 isoform 1, mature form (mouse)

mBMP7/iso:1/mature


"A bone morphogenetic protein 7 isoform 1, mature form in mouse. UniProtKB:P23359-1, 292-430." [PMID:12741987, PRO:CNA]

Yes

organism-modification



PR:000036518

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)

mBMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in mouse. UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160." [PMID:14623234, PRO:CNA, PRO:DAN]

Yes

modification



PR:000021902

bone morphogenetic protein 7 isoform 1, signal peptide removed form

BMP7/iso:1/SigPep-


"A bone morphogenetic protein 7 isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000612

bone morphogenetic protein 7 isoform 1, mature form

BMP7/iso:1/mature


"A bone morphogenetic protein 7 isoform 1 that has had the signal peptide and propeptide removed. Example: UniProtKB:P23359-1, 292-430." [PRO:CNA, PRO:DAN]


modification



PR:000000505

bone morphogenetic protein 7 isoform 1, mature glycosylated form

BMP7/iso:1/ClvGlyco+


"A bone morphogenetic protein 7 isoform 1, mature form that includes at least one glycosylated residue." [PRO:CNA, PRO:DAN]


modification



PR:000000613

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1

BMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature glycosylated form that is N-glycosylated at the N{P}[ST]{P} motif. This form is a disulfide linked homodimer. Example: UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]


organism-modification



PR:000036517

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human)

hBMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in human. UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15047707, PMID:15929982, PMID:8570652, PMID:9872992, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036518

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)

mBMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in mouse. UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160." [PMID:14623234, PRO:CNA, PRO:DAN]

Yes

modification



PR:000000614

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2

BMP7/iso:1/mature/NGlyco:2


"A bone morphogenetic protein 7 isoform 1, mature glycosylated form that has the propeptide still bound to the mature protein. This form is N-glycosylated at the most C-terminal N{P}[ST]{P} motif and is a homodimer. Example: UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982]


organism-modification



PR:000036519

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human)

hBMP7/iso:1/mature/NGlyco:2


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036516

bone morphogenetic protein 7 isoform 1, mature form (mouse)

mBMP7/iso:1/mature


"A bone morphogenetic protein 7 isoform 1, mature form in mouse. UniProtKB:P23359-1, 292-430." [PMID:12741987, PRO:CNA]

Yes

organism-modification



PR:000036518

bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (mouse)

mBMP7/iso:1/mature/NGlyco:1


"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in mouse. UniProtKB:P23359-1, 292-430, Asn-371, MOD:00160." [PMID:14623234, PRO:CNA, PRO:DAN]

Yes

modification



PR:000018288

bone morphogenetic protein 7 proteolytic cleavage product

BMP7/ClvPrd


"A bone morphogenetic protein 7 that has been processed by proteolytic cleavage." [PRO:DNx]


gene



PR:000000169

bone morphogenetic protein 8A

BMP8A


"A bone morphogenetic protein that is a translation product of the human BMP8A gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:Q1LWW7

uncharacterized protein, bmp8a translation product (zebrafish)

z-BMP8A


"A bone morphogenetic protein 8A that is encoded in the genome of zebrafish." [PRO:CNA]


organism-gene



PR:Q7Z5Y6

bone morphogenetic protein 8A (human)

hBMP8A


"A bone morphogenetic protein 8A that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q7Z5Y6]


organism-sequence



PR:Q7Z5Y6-1

bone morphogenetic protein 8A isoform 1 (human)

hBMP8A/iso:1


"A bone morphogenetic protein 8A isoform 1 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000000390

bone morphogenetic protein 8A isoform 1

BMP8A/iso:1


"A bone morphogenetic protein 8A that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z5Y6-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P34821-1

bone morphogenetic protein 8A isoform 1 (mouse)

mBMP8A/iso:1


"A bone morphogenetic protein 8A isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:Q7Z5Y6-1

bone morphogenetic protein 8A isoform 1 (human)

hBMP8A/iso:1


"A bone morphogenetic protein 8A isoform 1 that is encoded in the genome of human." [PRO:CNA]


gene



PR:000000170

bone morphogenetic protein 8B

BMP8B


"A bone morphogenetic protein that is a translation product of the human BMP8B gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:D3ZWC5

protein Bmp8b (rat)

rBMP8B


"A bone morphogenetic protein 8B that is encoded in the genome of rat." [PRO:CNA]


organism-gene



PR:P34820

bone morphogenetic protein 8B (human)

hBMP8B


"A bone morphogenetic protein 8B that is encoded in the genome of human." [PRO:CNA, UniProtKB:P34820]


organism-sequence



PR:P34820-1

bone morphogenetic protein 8B isoform 1 (human)

hBMP8B/iso:1


"A bone morphogenetic protein 8B isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:P34820-2

bone morphogenetic protein 8B isoform h2 (human)

hBMP8B/iso:h2


"A bone morphogenetic protein 8B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34820-2." [PRO:DNx, UniProtKB:P34820]


organism-modification



PR:000073065

bone morphogenetic protein 8B deaminated 1 (human)

hBMP8B/Deam:1


"A bone morphogenetic protein 8B (human) that has been deaminated on the residue at the position equivalent to Asn-158 of the amino acid sequence represented by UniProtKB:P34820-1. Example: UniProtKB:P34820-1, Asn-158, MOD:00684." [IEDB_epitope:1355860, IEDB_epitope:1361869, PRO:DNx]


organism-gene



PR:P55105

bone morphogenetic protein 8B (mouse)

mBMP8B


"A bone morphogenetic protein 8B that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:P55105-1

bone morphogenetic protein 8B isoform 1 (mouse)

mBMP8B/iso:1


"A bone morphogenetic protein 8B isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

sequence



PR:000000391

bone morphogenetic protein 8B isoform 1

BMP8B/iso:1


"A bone morphogenetic protein 8B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34820-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P34820-1

bone morphogenetic protein 8B isoform 1 (human)

hBMP8B/iso:1


"A bone morphogenetic protein 8B isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:P55105-1

bone morphogenetic protein 8B isoform 1 (mouse)

mBMP8B/iso:1


"A bone morphogenetic protein 8B isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

gene



PR:000007917

embryonic growth/differentiation factor 1

GDF1


"A bone morphogenetic protein that is a translation product of the human GDF1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P20863

embryonic growth/differentiation factor 1 (mouse)

mGDF1


"An embryonic growth/differentiation factor 1 that is encoded in the genome of mouse." [OMA:P20863, PRO:DNx]


organism-gene



PR:P27539

embryonic growth/differentiation factor 1 (human)

hGDF1


"An embryonic growth/differentiation factor 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P27539]


organism-modification



PR:000075064

embryonic growth/differentiation factor 1, mature form (human)

hGDF1/mature


"An embryonic growth/differentiation factor 1 (human) that has had the signal peptide and propeptide removed. UniProtKB:P27539, 254-372." [PRO:DNx, Reactome:R-HSA-1226025]


gene



PR:000007921

growth/differentiation factor 2

GDF2


"A bone morphogenetic protein that is a translation product of the human GDF2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:F1QWZ4

growth/differentiation factor 2 (zebrafish)

z-GDF2


"A growth/differentiation factor 2 that is encoded in the genome of zebrafish." [OMA:F1QWZ4, PRO:DNx]


organism-gene



PR:P34822

dorsalin-1 (chicken)

chick-GDF2


"A growth/differentiation factor 2 that is encoded in the genome of chicken." [OMA:P34822, PRO:DNx]


organism-gene



PR:Q9UK05

growth/differentiation factor 2 (human)

hGDF2


"A growth/differentiation factor 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UK05]


organism-modification



PR:000068554

growth/differentiation factor 2 cysteinylated 1 (human)

hGDF2/Cyst:1


"A growth/differentiation factor 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-327 of the amino acid sequence represented by UniProtKB:Q9UK05. UniProtKB:Q9UK05, Cys-327, MOD:00765." [IEDB_epitope:2121525, PRO:DNx]


organism-modification



PR:000085676

growth/differentiation factor 2, mature form (human)

hGDF2/mature


"A growth/differentiation factor 2 (human) that has had the signal peptide and propeptide removed. UniProtKB:Q9UK05, 320-429." [PRO:DNx, Reactome:R-HSA-3222335]


organism-gene



PR:Q9WV56

growth/differentiation factor 2 (mouse)

mGDF2


"A growth/differentiation factor 2 that is encoded in the genome of mouse." [OMA:Q9WV56, PRO:DNx]


gene



PR:000007922

growth/differentiation factor 3

GDF3


"A bone morphogenetic protein that is a translation product of the human GDF3 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q07104

growth/differentiation factor 3 (mouse)

mGDF3


"A growth/differentiation factor 3 that is encoded in the genome of mouse." [OMA:Q07104, PRO:DNx]


organism-gene



PR:Q9NR23

growth/differentiation factor 3 (human)

hGDF3


"A growth/differentiation factor 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NR23]


gene



PR:000007924

growth/differentiation factor 6

GDF6


"A bone morphogenetic protein that is a translation product of the human GDF6 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P43028

growth/differentiation factor 6 (mouse)

mGDF6


"A growth/differentiation factor 6 that is encoded in the genome of mouse." [OMA:P43028, PRO:DNx]


organism-gene



PR:P85857

growth/differentiation factor 6-A (zebrafish)

z-GDF6


"A growth/differentiation factor 6 that is encoded in the genome of zebrafish." [OMA:P85857, PRO:DNx]


organism-gene



PR:Q6HA10

growth/differentiation factor 6 (rat)

rGDF6


"A growth/differentiation factor 6 that is encoded in the genome of rat." [OMA:Q6HA10, PRO:DNx]


organism-gene



PR:Q6KF10

growth/differentiation factor 6 (human)

hGDF6


"A growth/differentiation factor 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q6KF10]


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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0001501 skeletal system developmentPR:000000164 BMP2 PANTHER:PTHR11848
PR:000000165 BMP4 PANTHER:PTHR11848
PR:000026336 hBMP2/iso:1/mature PMID:2315314
PR:000036510 mBMP2/iso:1/mature PMID:15565649; PMID:16109715
PR:000036514 hBMP6/iso:1/ClvNGlyco:1 PMID:12702725
PR:000036515 mBMP6/iso:1/ClvNGlyco:1 PMID:8089189
PR:P12643-1 hBMP2/iso:1 PMID:2315314
PR:P18075-1 hBMP7/iso:1 PMID:2357959
PR:P20722-1 mBMP6/iso:1 PMID:8089189
PR:P21275 mBMP4 PMID:14654219; PMID:15936012
PR:P22004-1 hBMP6/iso:1 PMID:12702725
PR:P34820-1 hBMP8B/iso:1 PMID:1460021
PR:P49003 mBMP5 PMID:2263636
GO:0001649 osteoblast differentiationPR:000036511 hBMP4/iso:1/mature PMID:14749725
PR:000036512 mBMP4/iso:1/mature PMID:15381701
GO:0001657 ureteric bud developmentPR:000036511 hBMP4/iso:1/mature PMID:12141440
PR:000036512 mBMP4/iso:1/mature PMID:12631064
GO:0001934 positive regulation of protein phosphorylationPR:000036511 hBMP4/iso:1/mature PMID:14749725
PR:000036514 hBMP6/iso:1/ClvNGlyco:1 PMID:16527843
GO:0007267 cell-cell signalingPR:000000164 BMP2 PANTHER:PTHR11848
PR:000026336 hBMP2/iso:1/mature PMID:2315314
PR:P12643-1 hBMP2/iso:1 PMID:2315314
GO:0007283 spermatogenesisPR:P34821-1 mBMP8A/iso:1 PMID:9463357
PR:P55105-1 mBMP8B/iso:1 PMID:8682296; PMID:9463357
GO:0007411 axon guidancePR:000036516 mBMP7/iso:1/mature PMID:12741987
GO:0007435 salivary gland morphogenesisPR:P23359 mBMP7 PMID:11731698
GO:0007498 mesoderm developmentPR:000036511 hBMP4/iso:1/mature PMID:9804553
PR:P12644-1 hBMP4/iso:1 PMID:9804553
GO:0007507 heart developmentPR:Q9R229-1 mBMP10/iso:1 PMID:15073151
GO:0009887 animal organ morphogenesisPR:P23359 mBMP7 PMID:7590254
GO:0030509 BMP signaling pathwayPR:000000164 BMP2 PANTHER:PTHR11848
PR:000036510 mBMP2/iso:1/mature PMID:14623234
PR:000036511 hBMP4/iso:1/mature PMID:12805376
PR:000036512 mBMP4/iso:1/mature PMID:14623234
PR:000036513 hBMP5/iso:1/mature PMID:11401399; PMID:14660436
PR:000036514 hBMP6/iso:1/ClvNGlyco:1 PMID:15969083
PR:000036515 mBMP6/iso:1/ClvNGlyco:1 PMID:14623234
PR:000036518 mBMP7/iso:1/mature/NGlyco:1 PMID:14623234
PR:P20722-1 mBMP6/iso:1 PMID:8089189
PR:P21274-1 mBMP2/iso:1 PMID:14623234
PR:P21275 mBMP4 PMID:14623234
PR:P22004-1 hBMP6/iso:1 PMID:12702725
PR:P23359-1 mBMP7/iso:1 PMID:14623234
PR:P34821-1 mBMP8A/iso:1 PMID:9463357
PR:P55105-1 mBMP8B/iso:1 PMID:11427739
GO:0032349 positive regulation of aldosterone biosynthetic processPR:000036514 hBMP6/iso:1/ClvNGlyco:1 PMID:16527843
GO:0035239 tube morphogenesisPR:P23359 mBMP7 PMID:15831470
GO:0042475 odontogenesis of dentin-containing toothPR:P23359 mBMP7 PMID:15525533
GO:0048754 branching morphogenesis of an epithelial tubePR:P23359 mBMP7 PMID:15831470

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0005102 signaling receptor bindingPR:000000034 fam:CBP-p300 PIRSF:PIRSF037272
PR:000026336 hBMP2/iso:1/mature PMID:2315314
PR:000036511 hBMP4/iso:1/mature PMID:11401399; PMID:14660436
PR:000036517 hBMP7/iso:1/mature/NGlyco:1 PMID:9872992
NOT GO:0005102 signaling receptor bindingPR:000036519 hBMP7/iso:1/mature/NGlyco:2 PMID:15929982
GO:0005125 cytokine activityPR:000000034 fam:CBP-p300 PIRSF:PIRSF037272
GO:0005515 protein bindingPR:000036516 mBMP7/iso:1/mature PMID:12741987
PR:P18075-1 hBMP7/iso:1 PMID:12805376
GO:0008083 growth factor activityPR:000000034 fam:CBP-p300 PIRSF:PIRSF037272
GO:0042803 protein homodimerization activityPR:000000034 fam:CBP-p300 PIRSF:PIRSF037272
PR:000026336 hBMP2/iso:1/mature PMID:10074410
PR:000036511 hBMP4/iso:1/mature PMID:12805376
PR:000036514 hBMP6/iso:1/ClvNGlyco:1 PMID:15969083; PMID:18070108
PR:000036517 hBMP7/iso:1/mature/NGlyco:1 PMID:15929982; PMID:8570652

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005615 extracellular spacePR:000026336 hBMP2/iso:1/mature PMID:2315314
PR:000036510 mBMP2/iso:1/mature PMID:15110716
PR:000036511 hBMP4/iso:1/mature PMID:12805376
PR:000036515 mBMP6/iso:1/ClvNGlyco:1 PMID:8089189
PR:000036516 mBMP7/iso:1/mature PMID:12741987
PR:000036517 hBMP7/iso:1/mature/NGlyco:1 PMID:15047707; PMID:15929982
PR:000036519 hBMP7/iso:1/mature/NGlyco:2 PMID:15929982
GO:0005622 intracellular anatomical structurePR:P12644-1 hBMP4/iso:1 PMID:12805376
GO:0005794 Golgi apparatusPR:P18075-1 hBMP7/iso:1 PMID:12805376