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Protein Ontology report - DNA-binding protein inhibitor ID-1
PR:000000039 - http://purl.obolibrary.org/obo/PR_000000039
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000039   
  PRO nameDNA-binding protein inhibitor ID-1 
  Synonyms
PRO-Short-label: EXACT:ID1
Gene-based: RELATED:BHLHB24 | ID | Id-1 | Idb1
Other: EXACT:bHLHb24 | class B basic helix-loop-helix protein 24 | inhibitor of differentiation 1 | inhibitor of DNA binding 1
  Definition"An HLH DNA-binding protein inhibitor that is a translation product of the human ID1 gene or a 1:1 ortholog thereof. This gene has two conserved protein coding exons." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000003 HLH DNA-binding protein inhibitor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF500477
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000000039

DNA-binding protein inhibitor ID-1

ID1


"An HLH DNA-binding protein inhibitor that is a translation product of the human ID1 gene or a 1:1 ortholog thereof. This gene has two conserved protein coding exons." [PRO:CNA]

Yes

organism-gene



PR:P20067

DNA-binding protein inhibitor ID-1 (mouse)

mID1


"A DNA-binding protein inhibitor ID-1 that is encoded in the genome of mouse." [OMA:P20067, PRO:DNx]

Yes

organism-sequence



PR:P20067-1

DNA-binding protein inhibitor ID-1 isoform Long (mouse)

mID1/iso:Long


"A DNA-binding protein inhibitor ID-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20067-1." [PRO:DNx, UniProtKB:P20067]


organism-sequence



PR:P20067-2

DNA-binding protein inhibitor ID-1 isoform Short (mouse)

mID1/iso:Short


"A DNA-binding protein inhibitor ID-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:P41134

DNA-binding protein inhibitor ID-1 (human)

hID1


"A DNA-binding protein inhibitor ID-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P41134]

Yes

organism-sequence



PR:P41134-1

DNA-binding protein inhibitor ID-1 isoform ID-A (human)

hID1/iso:ID-A


"A DNA-binding protein inhibitor ID-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:P41134-2

DNA-binding protein inhibitor ID-1 isoform ID-B (human)

hID1/iso:ID-B


"A DNA-binding protein inhibitor ID-1 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000071543

DNA-binding protein inhibitor ID-1 cysteinylated 1 (human)

hID1/Cyst:1


"A DNA-binding protein inhibitor ID-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-17 of the amino acid sequence represented by UniProtKB:P41134-1. Example: UniProtKB:P41134-1, Cys-17, MOD:00765." [IEDB_epitope:874821, PRO:DNx]


organism-gene



PR:P41135

DNA-binding protein inhibitor ID-1 (rat)

rID1


"A DNA-binding protein inhibitor ID-1 that is encoded in the genome of rat." [OMA:P41135, PRO:DNx]


organism-sequence



PR:P41135-1

DNA-binding protein inhibitor ID-1 isoform Long (rat)

rID1/iso:Long


"A DNA-binding protein inhibitor ID-1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41135-1." [PRO:DNx, UniProtKB:P41135]


organism-sequence



PR:P41135-2

DNA-binding protein inhibitor ID-1 isoform Short (rat)

rID1/iso:Short


"A DNA-binding protein inhibitor ID-1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41135-2." [PRO:DNx, UniProtKB:P41135]


sequence



PR:000000171

DNA-binding protein inhibitor ID-1 isoform 1

ID1/iso:1


"A DNA-binding protein inhibitor ID-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41134-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P20067-2

DNA-binding protein inhibitor ID-1 isoform Short (mouse)

mID1/iso:Short


"A DNA-binding protein inhibitor ID-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:P41134-1

DNA-binding protein inhibitor ID-1 isoform ID-A (human)

hID1/iso:ID-A


"A DNA-binding protein inhibitor ID-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

sequence



PR:000000172

DNA-binding protein inhibitor ID-1 isoform 2

ID1/iso:2


"A DNA-binding protein inhibitor ID-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41134-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P41134-2

DNA-binding protein inhibitor ID-1 isoform ID-B (human)

hID1/iso:ID-B


"A DNA-binding protein inhibitor ID-1 isoform 2 that is encoded in the genome of human." [PRO:CNA]


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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0000122 negative regulation of transcription by RNA polymerase IIPR:P20067 mID1 PMID:12498716
GO:0030509 BMP signaling pathwayPR:P20067 mID1 PMID:15820682
GO:0045892 negative regulation of DNA-templated transcriptionPR:P41134 hID1 PMID:15138269
GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transductionPR:P41134-1 hID1/iso:ID-A PMID:17855368

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0005515 protein bindingPR:P41134-1 hID1/iso:ID-A PMID:17855368
GO:0046983 protein dimerization activityPR:000000039 ID1 PANTHER:PTHR11723; PIRSF:PIRSF500477

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005634 nucleusPR:P41134 hID1 PMID:15138269
GO:0005737 cytoplasmPR:P41134-1 hID1/iso:ID-A PMID:17855368