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Protein Ontology report - activin receptor type-1B
PR:000000068 - http://purl.obolibrary.org/obo/PR_000000068
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000068   
  PRO nameactivin receptor type-1B 
  Synonyms
PRO-Short-label: EXACT:ACVR1B
Gene-based: RELATED:ACVRLK4 | ALK4
Other: EXACT:activin receptor type IB | activin receptor-like kinase 4 | ACTR-IB | ALK-4 | serine/threonine-protein kinase receptor R2 | SKR2
  Definition"A TGF-beta superfamily receptor type-1 that is a translation product of the human ACVR1B gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000006 TGF-beta superfamily receptor type-1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence3                                                  Organism-Sequence 6                                        
         Modification3                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1787
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000068 activin receptor type-1B
ACVR1B

organism-gene


PR:P36896 activin receptor type-1B (human)
hACVR1B

organism-sequence


PR:P36896-1 activin receptor type-1B isoform 1 (human)
hACVR1B/iso:1
Yes
organism-modification


PR:000036437 activin receptor type-1B isoform 1 phosphorylated 1 (human)
hACVR1B/iso:1/Phos:1
Yes
organism-modification


PR:000036438 activin receptor type-1B isoform 1 phosphorylated 2 (human)
hACVR1B/iso:1/Phos:2

organism-sequence


PR:P36896-2 activin receptor type-1B isoform 2 (human)
hACVR1B/iso:2
Yes
organism-sequence


PR:P36896-3 activin receptor type-1B isoform 3 (human)
hACVR1B/iso:3
Yes
organism-sequence


PR:P36896-4 activin receptor type-1B isoform h4 (human)
hACVR1B/iso:h4

organism-sequence


PR:P36896-5 activin receptor type-1B isoform h5 (human)
hACVR1B/iso:h5

organism-modification


PR:000046256 activin receptor type-1B, signal peptide removed form (human)
hACVR1B/SigPep-

organism-modification


PR:000046257 activin receptor type-1B, signal peptide removed phosphorylated 3 (human)
hACVR1B/SigPep-/Phos:3

organism-gene


PR:P80202 activin receptor type-1B (rat)
rACVR1B

organism-gene


PR:Q61271 activin receptor type-1B (mouse)
mACVR1B

organism-sequence


PR:Q61271-1 activin receptor type-1B isoform 1 (mouse)
mACVR1B/iso:1

sequence


PR:000000201 activin receptor type-1B isoform 1
ACVR1B/iso:1

organism-sequence


PR:P36896-1 activin receptor type-1B isoform 1 (human)
hACVR1B/iso:1
Yes
organism-modification


PR:000036437 activin receptor type-1B isoform 1 phosphorylated 1 (human)
hACVR1B/iso:1/Phos:1
Yes
organism-modification


PR:000036438 activin receptor type-1B isoform 1 phosphorylated 2 (human)
hACVR1B/iso:1/Phos:2

organism-sequence


PR:Q61271-1 activin receptor type-1B isoform 1 (mouse)
mACVR1B/iso:1

modification


PR:000000412 activin receptor type-1B isoform 1 phosphorylated form
ACVR1B/iso:1/PhosRes+

modification


PR:000000525 activin receptor type-1B isoform 1 phosphorylated 1
ACVR1B/iso:1/Phos:1

organism-modification


PR:000036437 activin receptor type-1B isoform 1 phosphorylated 1 (human)
hACVR1B/iso:1/Phos:1
Yes
modification


PR:000000526 activin receptor type-1B isoform 1 phosphorylated 2
ACVR1B/iso:1/Phos:2

organism-modification


PR:000036438 activin receptor type-1B isoform 1 phosphorylated 2 (human)
hACVR1B/iso:1/Phos:2

sequence


PR:000000202 activin receptor type-1B isoform 2
ACVR1B/iso:2

organism-sequence


PR:P36896-2 activin receptor type-1B isoform 2 (human)
hACVR1B/iso:2
Yes
sequence


PR:000000203 activin receptor type-1B isoform 3
ACVR1B/iso:3

organism-sequence


PR:P36896-3 activin receptor type-1B isoform 3 (human)
hACVR1B/iso:3
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006468 protein phosphorylationPR:000036437 hACVR1B/iso:1/Phos:1 PMID:12065756
GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathwayPR:P36896-1 hACVR1B/iso:1 PMID:11069203

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0016361 activin receptor activity, type IPR:000036437 hACVR1B/iso:1/Phos:1 PMID:8622651
NOT GO:0016361 activin receptor activity, type IPR:P36896-2 hACVR1B/iso:2 PMID:11117535; PMID:8636304
PR:P36896-3 hACVR1B/iso:3 PMID:11117535; PMID:8636304
GO:0046332 SMAD bindingPR:000036437 hACVR1B/iso:1/Phos:1 PMID:12065756

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005886 plasma membranePR:000036437 hACVR1B/iso:1/Phos:1 PMID:8397373
PR:P36896-2 hACVR1B/iso:2 PMID:11117535; PMID:8636304
PR:P36896-3 hACVR1B/iso:3 PMID:11117535; PMID:8636304
GO:0009986 cell surfacePR:000036437 hACVR1B/iso:1/Phos:1 PMID:12665502