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Protein Ontology report - cartilage oligomeric matrix protein
PR:000000085 - http://purl.obolibrary.org/obo/PR_000000085
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000085   
  PRO namecartilage oligomeric matrix protein 
  Synonyms
PRO-Short-label: EXACT:COMP
Other: EXACT:thrombospondin-5 | TSP5
  Definition"A thrombospondin subgroup B that is a translation product of the human COMP gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000030 thrombospondin subgroup B
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 36                                        
         Modification2                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000085 cartilage oligomeric matrix protein
COMP

organism-gene


PR:P35444 cartilage oligomeric matrix protein (rat)
rCOMP

organism-gene


PR:P49747 cartilage oligomeric matrix protein (human)
hCOMP

organism-sequence


PR:000000231 cartilage oligomeric matrix protein sequence variant P276R (human)
hCOMP/var:P276R
Yes
organism-sequence


PR:000000232 cartilage oligomeric matrix protein sequence variant C387G (human)
hCOMP/var:C387G
Yes
organism-sequence


PR:000000233 cartilage oligomeric matrix protein sequence variant D408Y (human)
hCOMP/var:D408Y
Yes
organism-sequence


PR:000000234 cartilage oligomeric matrix protein sequence variant D420A (human)
hCOMP/var:D420A
Yes
organism-sequence


PR:000000235 cartilage oligomeric matrix protein sequence variant G440E (human)
hCOMP/var:G440E
Yes
organism-sequence


PR:000000236 cartilage oligomeric matrix protein sequence variant G440R (human)
hCOMP/var:G440R
Yes
organism-sequence


PR:000000237 cartilage oligomeric matrix protein sequence variant N453S (human)
hCOMP/var:N453S
Yes
organism-sequence


PR:000000238 cartilage oligomeric matrix protein sequence variant D439V (human)
hCOMP/var:D439V
Yes
organism-sequence


PR:000000239 cartilage oligomeric matrix protein sequence variant C468Y (human)
hCOMP/var:C468Y
Yes
organism-sequence


PR:000000240 cartilage oligomeric matrix protein sequence variant D472Y (human)
hCOMP/var:D472Y
Yes
organism-sequence


PR:000000241 cartilage oligomeric matrix protein sequence variant D473G (human)
hCOMP/var:D473G
Yes
organism-sequence


PR:000000242 cartilage oligomeric matrix protein sequence variant D290N (human)
hCOMP/var:D290N
Yes
organism-sequence


PR:000000243 cartilage oligomeric matrix protein sequence variant D482G (human)
hCOMP/var:D482G
Yes
organism-sequence


PR:000000244 cartilage oligomeric matrix protein sequence variant D518N (human)
hCOMP/var:D518N
Yes
organism-sequence


PR:000000245 cartilage oligomeric matrix protein sequence variant G719D (human)
hCOMP/var:G719D
Yes
organism-sequence


PR:000000246 cartilage oligomeric matrix protein sequence variant N523K (human)
hCOMP/var:N523K
Yes
organism-sequence


PR:000000247 cartilage oligomeric matrix protein sequence variant T585M (human)
hCOMP/var:T585M
Yes
organism-sequence


PR:000000248 cartilage oligomeric matrix protein sequence variant T585R (human)
hCOMP/var:T585R
Yes
organism-sequence


PR:000000249 cartilage oligomeric matrix protein sequence variant 26 (human)
hCOMP/var:26
Yes
organism-sequence


PR:000000250 cartilage oligomeric matrix protein sequence variant D372del (human)
hCOMP/var:D372del
Yes
organism-sequence


PR:000000251 cartilage oligomeric matrix protein sequence variant D374del (human)
hCOMP/var:D374del
Yes
organism-sequence


PR:000000252 cartilage oligomeric matrix protein sequence variant S459del (human)
hCOMP/var:S459del
Yes
organism-sequence


PR:000000253 cartilage oligomeric matrix protein sequence variant G299R (human)
hCOMP/var:G299R
Yes
organism-sequence


PR:000000254 cartilage oligomeric matrix protein sequence variant D469del (human)
hCOMP/var:D469del
Yes
organism-sequence


PR:000000255 cartilage oligomeric matrix protein sequence variant D473del (human)
hCOMP/var:D473del
Yes
organism-sequence


PR:000000256 cartilage oligomeric matrix protein sequence variant 32 (human)
hCOMP/var:32
Yes
organism-sequence


PR:000000257 cartilage oligomeric matrix protein sequence variant 33 (human)
hCOMP/var:33
Yes
organism-sequence


PR:000000258 cartilage oligomeric matrix protein sequence variant C328R (human)
hCOMP/var:C328R
Yes
organism-sequence


PR:000000259 cartilage oligomeric matrix protein sequence variant D342Y (human)
hCOMP/var:D342Y
Yes
organism-sequence


PR:000000260 cartilage oligomeric matrix protein sequence variant C348R (human)
hCOMP/var:C348R
Yes
organism-sequence


PR:000000261 cartilage oligomeric matrix protein sequence variant D361V (human)
hCOMP/var:D361V
Yes
organism-sequence


PR:000000262 cartilage oligomeric matrix protein sequence variant D361Y (human)
hCOMP/var:D361Y
Yes
organism-sequence


PR:000000263 cartilage oligomeric matrix protein sequence variant C371S (human)
hCOMP/var:C371S
Yes
organism-sequence


PR:P49747-1 cartilage oligomeric matrix protein isoform 1 (human)
hCOMP/iso:1
Yes
organism-modification


PR:000036452 cartilage oligomeric matrix protein isoform 1, signal peptide removed form (human)
hCOMP/iso:1/SigPep-
Yes
organism-sequence


PR:P49747-2 cartilage oligomeric matrix protein isoform h2 (human)
hCOMP/iso:h2

organism-modification


PR:000056586 cartilage oligomeric matrix protein N-glycosylated 1 (human)
hCOMP/NGlyco:1

organism-modification


PR:000056587 cartilage oligomeric matrix protein N-glycosylated 2 (human)
hCOMP/NGlyco:2

organism-modification


PR:000068189 cartilage oligomeric matrix protein deaminated 1 (human)
hCOMP/Deam:1

organism-modification


PR:000073868 cartilage oligomeric matrix protein deaminated 2 (human)
hCOMP/Deam:2

organism-modification


PR:000085876 cartilage oligomeric matrix protein, signal peptide removed form (human)
hCOMP/SigPep-

organism-modification


PR:000036452 cartilage oligomeric matrix protein isoform 1, signal peptide removed form (human)
hCOMP/iso:1/SigPep-
Yes
organism-gene


PR:Q9R0G6 cartilage oligomeric matrix protein (mouse)
mCOMP

organism-sequence


PR:Q9R0G6-1 cartilage oligomeric matrix protein isoform 1 (mouse)
mCOMP/iso:1

sequence


PR:000000230 cartilage oligomeric matrix protein isoform 1
COMP/iso:1

organism-sequence


PR:P49747-1 cartilage oligomeric matrix protein isoform 1 (human)
hCOMP/iso:1
Yes
organism-modification


PR:000036452 cartilage oligomeric matrix protein isoform 1, signal peptide removed form (human)
hCOMP/iso:1/SigPep-
Yes
organism-sequence


PR:Q9R0G6-1 cartilage oligomeric matrix protein isoform 1 (mouse)
mCOMP/iso:1

modification


PR:000000540 cartilage oligomeric matrix protein isoform 1, signal peptide removed form
COMP/iso:1/SigPep-

organism-modification


PR:000036452 cartilage oligomeric matrix protein isoform 1, signal peptide removed form (human)
hCOMP/iso:1/SigPep-
Yes
modification


PR:000025416 cartilage oligomeric matrix protein proteolytic cleavage product
COMP/ClvPrd

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000231 hCOMP/var:P276R
Example: UniProtKB:P49747-1, Pro-276, CHEBI:29952		 associated_with_disease_progressionDO:12721 multiple epiphyseal dysplasia PMID:11565064
PR:000000232 hCOMP/var:C387G
Example: UniProtKB:P49747-1, Cys-387, CHEBI:29947		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007625
PR:000000233 hCOMP/var:D408Y
Example: UniProtKB:P49747-1, Asp-408, CHEBI:46858		 associated_with_disease_progressionDO:12721 multiple epiphyseal dysplasia PMID:9452026
PR:000000234 hCOMP/var:D420A
Example: UniProtKB:P49747-1, Asp-420, CHEBI:46217		 associated_with_disease_progressionDO:12721 multiple epiphyseal dysplasia PMID:11565064
PR:000000235 hCOMP/var:G440E
Example: UniProtKB:P49747-1, Gly-440, CHEBI:29972		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007628
PR:000000236 hCOMP/var:G440R
Example: UniProtKB:P49747-1, Gly-440, CHEBI:29952		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia PMID:9452026
PR:000000237 hCOMP/var:N453S
Example: UniProtKB:P49747-1, Asn-453, CHEBI:29999		 associated_with_disease_progressionDO:12721 multiple epiphyseal dysplasia UniProtKB_VAR:VAR_007630
PR:000000238 hCOMP/var:D439V
Example: UniProtKB:P49747-1, Asp-439, CHEBI:30015		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007618
PR:000000239 hCOMP/var:C468Y
Example: UniProtKB:P49747-1, Cys-468, CHEBI:46858		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia PMID:7670471; PMID:9452026
PR:000000240 hCOMP/var:D472Y
Example: UniProtKB:P49747-1, Asp-472, CHEBI:46858		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia PMID:7670471; PMID:9452026
PR:000000241 hCOMP/var:D473G
Example: UniProtKB:P49747-1, Asp-473, CHEBI:29947		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007635
PR:000000242 hCOMP/var:D290N
Example: UniProtKB:P49747-1, Asp-290, CHEBI:50347		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007614
PR:000000243 hCOMP/var:D482G
Example: UniProtKB:P49747-1, Asp-482, CHEBI:29947		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia PMID:9452063
PR:000000244 hCOMP/var:D518N
Example: UniProtKB:P49747-1, Asp-518, CHEBI:50347		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007639
PR:000000245 hCOMP/var:G719D
Example: UniProtKB:P49747-1, Gly-719, CHEBI:29958		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia PMID:11746044
PR:000000246 hCOMP/var:N523K
Example: UniProtKB:P49747-1, Asn-523, CHEBI:29967		 associated_with_disease_progressionDO:12721 multiple epiphyseal dysplasia PMID:9021009
PR:000000247 hCOMP/var:T585M
Example: UniProtKB:P49747-1, Thr-585, CHEBI:16044		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia PMID:11565064
DO:12721 multiple epiphyseal dysplasia PMID:11565064
PR:000000248 hCOMP/var:T585R
Example: UniProtKB:P49747-1, Thr-585, CHEBI:29952		 associated_with_disease_progressionDO:12721 multiple epiphyseal dysplasia UniProtKB_VAR:VAR_007642
PR:000000249 hCOMP/var:26 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007626
PR:000000250 hCOMP/var:D372del
Example: UniProtKB:P49747-1, 21-371, 373-757		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007623
PR:000000251 hCOMP/var:D374del
Example: UniProtKB:P49747-1, 21-373, 375-757		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007624
PR:000000252 hCOMP/var:S459del
Example: UniProtKB:P49747-1, 21-458, 460-757		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007631
PR:000000253 hCOMP/var:G299R
Example: UniProtKB:P49747-1, Gly-299, CHEBI:29952		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007615
PR:000000254 hCOMP/var:D469del
Example: UniProtKB:P49747-1, 21-468, 470-757		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007633
PR:000000255 hCOMP/var:D473del
Example: UniProtKB:P49747-1, 21-472, 474-757		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007636
PR:000000256 hCOMP/var:32
Example: UniProtKB:P49747-1, 21-366, 369-757		 associated_with_disease_progressionDO:12721 multiple epiphyseal dysplasia UniProtKB_VAR:VAR_007621
PR:000000257 hCOMP/var:33
Example: UniProtKB:P49747-1, 21-512, 517-757		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007638
PR:000000258 hCOMP/var:C328R
Example: UniProtKB:P49747-1, Cys-328, CHEBI:29952		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia UniProtKB_VAR:VAR_007616
PR:000000259 hCOMP/var:D342Y
Example: UniProtKB:P49747-1, Asp-342, CHEBI:46858		 associated_with_disease_progressionDO:12721 multiple epiphyseal dysplasia PMID:7670472; PMID:9452026
PR:000000260 hCOMP/var:C348R
Example: UniProtKB:P49747-1, Cys-348, CHEBI:29952		 associated_with_disease_progressionDO:0080047 pseudoachondroplasia PMID:11746045
PR:000000261 hCOMP/var:D361V
Example: UniProtKB:P49747-1, Asp-361, CHEBI:30015		 associated_with_disease_progressionDO:12721 multiple epiphyseal dysplasia UniProtKB_VAR:VAR_007619
PR:000000262 hCOMP/var:D361Y
Example: UniProtKB:P49747-1, Asp-361, CHEBI:46858		 associated_with_disease_progressionDO:12721 multiple epiphyseal dysplasia PMID:9452026
PR:000000263 hCOMP/var:C371S
Example: UniProtKB:P49747-1, Cys-371, CHEBI:29999		 associated_with_disease_progressionDO:12721 multiple epiphyseal dysplasia PMID:9184241
PR:000036452 hCOMP/iso:1/SigPep-
UniProtKB:P49747-1, 21-757		 acts_upstream_of_or_withinGO:0009887 animal organ morphogenesis PMID:7713493
enablesGO:0005201 extracellular matrix structural constituent PMID:9749943
GO:0005509 calcium ion binding PMID:7670472
located_inGO:0031012 extracellular matrix PMID:9749943
PR:P49747-1 hCOMP/iso:1 acts_upstream_of_or_withinGO:0001501 skeletal system development PMID:7670472
GO:0009887 animal organ morphogenesis PMID:7713493