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Protein Ontology report - chordin isoform 1
PR:000000086 - http://purl.obolibrary.org/obo/PR_000000086
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000086   
  PRO namechordin isoform 1 
  Synonyms
PRO-Short-label: EXACT:CHRD/iso:1
  Definition"A chordin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H2X0-1 or a 1:1 ortholog thereof." [PMID:10479448, PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000010 chordin
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 3                                        
         Modification2                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
sequence



PR:000000086

chordin isoform 1

CHRD/iso:1


"A chordin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H2X0-1 or a 1:1 ortholog thereof." [PMID:10479448, PRO:CNA, PRO:DAN]


organism-sequence



PR:Q91713-1

chordin isoform 1 (frog)

frog-CHRD/iso:1


"A chordin isoform 1 that is encoded in the genome of frog." [PRO:DAN]


organism-modification



PR:000036410

chordin isoform 1, signal peptide removed form (frog)

frog-CHRD/iso:1/SigPep-


"A chordin isoform 1, signal peptide removed form in frog. UniProtKB:Q91713-1, 20-941." [PMID:8752213, PRO:CNA]

Yes

organism-sequence



PR:Q9H2X0-1

chordin isoform 1 (human)

hCHRD/iso:1


"A chordin isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-sequence



PR:Q9Z0E2-1

chordin isoform 1 (mouse)

mCHRD/iso:1


"A chordin isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-modification



PR:000036409

chordin isoform 1, signal peptide removed form (mouse)

mCHRD/iso:1/SigPep-


"A chordin isoform 1, signal peptide removed form in mouse. UniProtKB:Q9Z0E2-1, 27-948." [PMID:10479448, PMID:11784076, PMID:15381701, PMID:15780974, PRO:CNA]

Yes

organism-modification



PR:000036411

chordin isoform 1 cleaved 2 (mouse)

mCHRD/iso:1/Clv:2


"A chordin isoform 1 cleaved 2 in mouse. UniProtKB:Q9Z0E2-1, 154-861." [PMID:10479448, PRO:CNA]

Yes

modification



PR:000000424

chordin isoform 1, signal peptide removed form

CHRD/iso:1/SigPep-


"A chordin isoform 1 that has had the signal peptide removed." [PRO:CNA]


organism-modification



PR:000036409

chordin isoform 1, signal peptide removed form (mouse)

mCHRD/iso:1/SigPep-


"A chordin isoform 1, signal peptide removed form in mouse. UniProtKB:Q9Z0E2-1, 27-948." [PMID:10479448, PMID:11784076, PMID:15381701, PMID:15780974, PRO:CNA]

Yes

organism-modification



PR:000036410

chordin isoform 1, signal peptide removed form (frog)

frog-CHRD/iso:1/SigPep-


"A chordin isoform 1, signal peptide removed form in frog. UniProtKB:Q91713-1, 20-941." [PMID:8752213, PRO:CNA]

Yes

modification



PR:000000425

chordin isoform 1 cleaved 2

CHRD/iso:1/Clv:2


"A chordin isoform 1 that has been cleaved by BMP1 at two sites upstream of Asp residues. One site is within the motif Y[SN]DR, whereas the other is within the motif MQ[AS]DG. This form activates BMP signaling pathway. Example: UniProtKB:Q9Z0E2-1, 154-861." [PMID:10479448, UniProtKB:Q9Z0E2]


organism-modification



PR:000036411

chordin isoform 1 cleaved 2 (mouse)

mCHRD/iso:1/Clv:2


"A chordin isoform 1 cleaved 2 in mouse. UniProtKB:Q9Z0E2-1, 154-861." [PMID:10479448, PRO:CNA]

Yes

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0001501 skeletal system developmentPR:000036409 mCHRD/iso:1/SigPep- PMID:11784076
PR:000036411 mCHRD/iso:1/Clv:2 PMID:10479448
PR:Q9H2X0-1 hCHRD/iso:1 PMID:9782094
GO:0030514 negative regulation of BMP signaling pathwayPR:000036409 mCHRD/iso:1/SigPep- PMID:10479448; PMID:15780974

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0005515 protein bindingPR:000036409 mCHRD/iso:1/SigPep- PMID:15381701
GO:0008201 heparin bindingPR:000036409 mCHRD/iso:1/SigPep- PMID:15381701

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005615 extracellular spacePR:000036409 mCHRD/iso:1/SigPep- PMID:15780974
PR:000036410 frog-CHRD/iso:1/SigPep- PMID:8752213
PR:000036411 mCHRD/iso:1/Clv:2 PMID:10479448
GO:0032991 protein-containing complexPR:000036410 frog-CHRD/iso:1/SigPep- PMID:8752213