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gene
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 PR:000000121 |
   Rho-associated protein kinase 2
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   ROCK2
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  "A Rho-associated protein kinase that is a translation product of the human ROCK2 gene or a 1:1 ortholog thereof." [PRO:CNA]
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organism-gene
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 PR:O75116 |
   Rho-associated protein kinase 2 (human)
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   hROCK2
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  "A Rho-associated protein kinase 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O75116]
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organism-sequence
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 PR:O75116-1 |
   Rho-associated protein kinase 2 isoform 1 (human)
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   hROCK2/iso:1
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  "A Rho-associated protein kinase 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000036477 |
   Rho-associated protein kinase 2 isoform 1 cleaved 1 (human)
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   hROCK2/iso:1/Clv:1
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  "A Rho-associated protein kinase 2 isoform 1 cleaved 1 in human. UniProtKB:O75116-1, 1-1131." [PMID:15699075, PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000036478 |
   Rho-associated protein kinase 2 isoform 1 phosphorylated 1 (human)
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   hROCK2/iso:1/Phos:1
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  "A Rho-associated protein kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046." [PMID:15302935, PMID:17446864, PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000036479 |
   Rho-associated protein kinase 2 isoform 1 phosphorylated 2 (human)
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   hROCK2/iso:1/Phos:2
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  "A Rho-associated protein kinase 2 isoform 1 phosphorylated 2 in human. UniProtKB:O75116-1, Thr-1078, MOD:00047." [PMID:17525332, PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000066276 |
   Rho-associated protein kinase 2 methylated 1 (human)
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   hROCK2/Me:1
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  "A Rho-associated protein kinase 2 (human) that has been methylated on the residue at the position equivalent to Cys-236 of the amino acid sequence represented by UniProtKB:O75116. UniProtKB:O75116, Cys-236, MOD:00660." [IEDB_epitope:1024569, PRO:DNx]
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organism-modification
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 PR:000071951 |
   Rho-associated protein kinase 2 methylated 2 (human)
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   hROCK2/Me:2
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  "A Rho-associated protein kinase 2 (human) that has been methylated on the residue at the position equivalent to Cys-1315 of the amino acid sequence represented by UniProtKB:O75116. UniProtKB:O75116, Cys-1315, MOD:00660." [IEDB_epitope:1020710, PRO:DNx]
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organism-modification
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 PR:000074887 |
   Rho-associated protein kinase 2 phosphorylated 1 (human)
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   hROCK2/Phos:1
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  "A Rho-associated protein kinase 2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1379 of the amino acid sequence represented by UniProtKB:O75116. UniProtKB:O75116, Ser-1379, MOD:00046." [IEDB_epitope:2147201, PRO:DNx]
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organism-gene
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 PR:P70336 |
   Rho-associated protein kinase 2 (mouse)
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   mROCK2
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  "A Rho-associated protein kinase 2 that is encoded in the genome of mouse." [OMA:P70336, PRO:DNx]
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organism-sequence
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 PR:P70336-1 |
   Rho-associated protein kinase 2 isoform 1 (mouse)
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   mROCK2/iso:1
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  "A Rho-associated protein kinase 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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organism-sequence
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 PR:P70336-2 |
   Rho-associated protein kinase 2 isoform 2 (mouse)
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   mROCK2/iso:2
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  "A Rho-associated protein kinase 2 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
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 Yes | 
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organism-gene
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 PR:Q62868 |
   Rho-associated protein kinase 2 (rat)
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   rROCK2
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  "A Rho-associated protein kinase 2 that is encoded in the genome of rat." [OMA:Q62868, PRO:DNx]
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sequence
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 PR:000000308 |
   Rho-associated protein kinase 2 isoform 1
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   ROCK2/iso:1
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  "A Rho-associated protein kinase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75116-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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 PR:O75116-1 |
   Rho-associated protein kinase 2 isoform 1 (human)
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   hROCK2/iso:1
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  "A Rho-associated protein kinase 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000036477 |
   Rho-associated protein kinase 2 isoform 1 cleaved 1 (human)
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   hROCK2/iso:1/Clv:1
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  "A Rho-associated protein kinase 2 isoform 1 cleaved 1 in human. UniProtKB:O75116-1, 1-1131." [PMID:15699075, PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000036478 |
   Rho-associated protein kinase 2 isoform 1 phosphorylated 1 (human)
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   hROCK2/iso:1/Phos:1
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  "A Rho-associated protein kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046." [PMID:15302935, PMID:17446864, PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000036479 |
   Rho-associated protein kinase 2 isoform 1 phosphorylated 2 (human)
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   hROCK2/iso:1/Phos:2
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  "A Rho-associated protein kinase 2 isoform 1 phosphorylated 2 in human. UniProtKB:O75116-1, Thr-1078, MOD:00047." [PMID:17525332, PRO:CNA]
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 Yes | 
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organism-sequence
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 PR:P70336-1 |
   Rho-associated protein kinase 2 isoform 1 (mouse)
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   mROCK2/iso:1
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  "A Rho-associated protein kinase 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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modification
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 PR:000000462 |
   Rho-associated protein kinase 2 isoform 1 phosphorylated form
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   ROCK2/iso:1/PhosRes+
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  "A Rho-associated protein kinase 2 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
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modification
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 PR:000000565 |
   Rho-associated protein kinase 2 isoform 1 phosphorylated 1
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   ROCK2/iso:1/Phos:1
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  "A Rho-associated protein kinase 2 isoform 1 phosphorylated form in which the phosphorylation occurs within the C-terminal region by the action of serine/threonine-protein kinase PLK1." [PMID:17446864]
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organism-modification
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 PR:000036478 |
   Rho-associated protein kinase 2 isoform 1 phosphorylated 1 (human)
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   hROCK2/iso:1/Phos:1
 |
  "A Rho-associated protein kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:O75116-1, Ser-1134/Ser-1137, MOD:00046." [PMID:15302935, PMID:17446864, PRO:CNA]
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 Yes | 
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modification
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 PR:000000566 |
   Rho-associated protein kinase 2 isoform 1 phosphorylated 2
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   ROCK2/iso:1/Phos:2
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  "A Rho-associated protein kinase 2 isoform 1 phosphorylated form that has been induced by DNA damage. Example: UniProtKB:O75116-1, Thr-1078, MOD:00047." [PMID:17525332, PRO:CNA, PRO:DAN]
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organism-modification
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 PR:000036479 |
   Rho-associated protein kinase 2 isoform 1 phosphorylated 2 (human)
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   hROCK2/iso:1/Phos:2
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  "A Rho-associated protein kinase 2 isoform 1 phosphorylated 2 in human. UniProtKB:O75116-1, Thr-1078, MOD:00047." [PMID:17525332, PRO:CNA]
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 Yes | 
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modification
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 PR:000000564 |
   Rho-associated protein kinase 2 isoform 1 cleaved 1
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   ROCK2/iso:1/Clv:1
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  "A Rho-associated protein kinase 2 isoform 1 that has been cleaved in the granzyme B consensus motif [IVL][GE]xD located between the Rho binding and the PH domains, removing the C-terminus." [PRO:CNA]
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organism-modification
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 PR:000036477 |
   Rho-associated protein kinase 2 isoform 1 cleaved 1 (human)
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   hROCK2/iso:1/Clv:1
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  "A Rho-associated protein kinase 2 isoform 1 cleaved 1 in human. UniProtKB:O75116-1, 1-1131." [PMID:15699075, PRO:CNA]
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 Yes | 
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modification
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 PR:000002530 |
   Rho-associated protein kinase 2 isoform 1 unmodified form
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   ROCK2/iso:1/UnMod
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  "A Rho-associated protein kinase 2 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
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sequence
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 PR:000000309 |
   Rho-associated protein kinase 2 isoform 2
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   ROCK2/iso:2
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  "A Rho-associated protein kinase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70336-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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 PR:P70336-2 |
   Rho-associated protein kinase 2 isoform 2 (mouse)
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   mROCK2/iso:2
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  "A Rho-associated protein kinase 2 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
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 Yes | 
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modification
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 PR:000025436 |
   Rho-associated protein kinase 2 proteolytic cleavage product
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   ROCK2/ClvPrd
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  "A Rho-associated protein kinase 2 that has been processed by proteolytic cleavage." [PRO:DNx]
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modification
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 PR:000000564 |
   Rho-associated protein kinase 2 isoform 1 cleaved 1
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   ROCK2/iso:1/Clv:1
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  "A Rho-associated protein kinase 2 isoform 1 that has been cleaved in the granzyme B consensus motif [IVL][GE]xD located between the Rho binding and the PH domains, removing the C-terminus." [PRO:CNA]
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organism-modification
 |


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 PR:000036477 |
   Rho-associated protein kinase 2 isoform 1 cleaved 1 (human)
 |
   hROCK2/iso:1/Clv:1
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  "A Rho-associated protein kinase 2 isoform 1 cleaved 1 in human. UniProtKB:O75116-1, 1-1131." [PMID:15699075, PRO:CNA]
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 Yes | 
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