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Protein Ontology report - zinc finger FYVE domain-containing protein 9
PR:000000125 - http://purl.obolibrary.org/obo/PR_000000125
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000125   
  PRO namezinc finger FYVE domain-containing protein 9 
  Synonyms
PRO-Short-label: EXACT:ZFYVE9
Gene-based: RELATED:MADHIP | SARA | SMADIP
Other: EXACT:Madh-interacting protein | mothers against decapentaplegic homolog-interacting protein | novel serine protease | receptor activation anchor | smad anchor for receptor activation
RELATED:NSP
  Definition"A sara-type zinc finger FYVE domain-containing protein that is a translation product of the human ZFYVE9 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000026 sara-type zinc finger FYVE domain-containing protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence3                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000125 zinc finger FYVE domain-containing protein 9
ZFYVE9
Yes
Yes
organism-gene


PR:000029965 zinc finger FYVE domain-containing protein 9 (mouse)
mZFYVE9

organism-sequence


PR:A2A8R0 zinc finger FYVE domain-containing protein 9 isoform 1 (mouse)
mZFYVE9/iso:1

organism-sequence


PR:A8Y5G5 zinc finger FYVE domain-containing protein 9 isoform 2 (mouse)
mZFYVE9/iso:2

organism-gene


PR:O95405 zinc finger FYVE domain-containing protein 9 (human)
hZFYVE9

Yes
organism-sequence


PR:O95405-1 zinc finger FYVE domain-containing protein 9 isoform 1 (human)
hZFYVE9/iso:1
Yes
organism-sequence


PR:O95405-2 zinc finger FYVE domain-containing protein 9 isoform 2 (human)
hZFYVE9/iso:2
Yes
organism-sequence


PR:O95405-3 zinc finger FYVE domain-containing protein 9 isoform 3 (human)
hZFYVE9/iso:3
Yes
sequence


PR:000000313 zinc finger FYVE domain-containing protein 9 isoform 1
ZFYVE9/iso:1

organism-sequence


PR:A2A8R0 zinc finger FYVE domain-containing protein 9 isoform 1 (mouse)
mZFYVE9/iso:1

organism-sequence


PR:O95405-1 zinc finger FYVE domain-containing protein 9 isoform 1 (human)
hZFYVE9/iso:1
Yes
modification


PR:000002535 zinc finger FYVE domain-containing protein 9 isoform 1 unmodified form
ZFYVE9/iso:1/UnMod

sequence


PR:000000314 zinc finger FYVE domain-containing protein 9 isoform 2
ZFYVE9/iso:2

organism-sequence


PR:A8Y5G5 zinc finger FYVE domain-containing protein 9 isoform 2 (mouse)
mZFYVE9/iso:2

organism-sequence


PR:O95405-2 zinc finger FYVE domain-containing protein 9 isoform 2 (human)
hZFYVE9/iso:2
Yes
sequence


PR:000000315 zinc finger FYVE domain-containing protein 9 isoform 3
ZFYVE9/iso:3

organism-sequence


PR:O95405-3 zinc finger FYVE domain-containing protein 9 isoform 3 (human)
hZFYVE9/iso:3
Yes
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ZFYVE9 forms found in complexes   

ZFYVE9 Component
 Complexes
PR:000000125 ZFYVE9 PR:000025974 TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex
PR:O95405 hZFYVE9 PR:000025965 TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000125 ZFYVE9 acts_upstream_of_or_withinGO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway PANTHER:PTHR22835
PR:O95405-1 hZFYVE9/iso:1 acts_upstream_of_or_withinGO:0006897 endocytosis PMID:12809483
GO:0007179 transforming growth factor beta receptor signaling pathway PMID:10615055
GO:0060390 regulation of SMAD protein signal transduction PMID:11877415; PMID:12356868
GO:0060395 SMAD protein signal transduction PMID:11877415; PMID:12356868
enablesGO:0005515 protein binding with PR:000025960 hSMAD2/iso:[Long/Short]/UnPhos:1 PMID:17693260
GO:0005515 protein binding with PR:P08100 hRHO PMID:17693260
located_inGO:0005769 early endosome PMID:11877415; PMID:12356868; PMID:12432064
PR:O95405-2 hZFYVE9/iso:2 located_inGO:0005615 extracellular space PMID:9582421
PR:O95405-3 hZFYVE9/iso:3 located_inGO:0005615 extracellular space PMID:9582421