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Protein Ontology report - zinc finger FYVE domain-containing protein 9
PR:000000125 - http://purl.obolibrary.org/obo/PR_000000125
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000125   
  PRO namezinc finger FYVE domain-containing protein 9 
  Synonyms
PRO-Short-label: EXACT:ZFYVE9
Gene-based: RELATED:MADHIP | SARA | SMADIP
Other: EXACT:Madh-interacting protein | mothers against decapentaplegic homolog-interacting protein | novel serine protease | receptor activation anchor | smad anchor for receptor activation
RELATED:NSP
  Definition"A sara-type zinc finger FYVE domain-containing protein that is a translation product of the human ZFYVE9 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000026 sara-type zinc finger FYVE domain-containing protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence3                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000125
zinc finger FYVE domain-containing protein 9
ZFYVE9
"A sara-type zinc finger FYVE domain-containing protein that is a translation product of the human ZFYVE9 gene or a 1:1 ortholog thereof." [PRO:CNA]
Yes
Yes
organism-gene


PR:000029965
zinc finger FYVE domain-containing protein 9 (mouse)
mZFYVE9
"A zinc finger FYVE domain-containing protein 9 that is encoded in the genome of mouse." [PRO:DAN]

organism-sequence


PR:A2A8R0
zinc finger FYVE domain-containing protein 9 isoform 1 (mouse)
mZFYVE9/iso:1
"A zinc finger FYVE domain-containing protein 9 isoform 1 that is encoded in the genome of mouse." [PRO:DAN]

organism-sequence


PR:A8Y5G5
zinc finger FYVE domain-containing protein 9 isoform 2 (mouse)
mZFYVE9/iso:2
"A zinc finger FYVE domain-containing protein 9 isoform 2 that is encoded in the genome of mouse." [PRO:DAN]

organism-gene


PR:O95405
zinc finger FYVE domain-containing protein 9 (human)
hZFYVE9
"A zinc finger FYVE domain-containing protein 9 that is encoded in the genome of human." [PRO:CNA]

Yes
organism-sequence


PR:O95405-1
zinc finger FYVE domain-containing protein 9 isoform 1 (human)
hZFYVE9/iso:1
"A zinc finger FYVE domain-containing protein 9 isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-sequence


PR:O95405-2
zinc finger FYVE domain-containing protein 9 isoform 2 (human)
hZFYVE9/iso:2
"A zinc finger FYVE domain-containing protein 9 isoform 2 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-sequence


PR:O95405-3
zinc finger FYVE domain-containing protein 9 isoform 3 (human)
hZFYVE9/iso:3
"A zinc finger FYVE domain-containing protein 9 isoform 3 that is encoded in the genome of human." [PRO:CNA]
Yes
sequence


PR:000000313
zinc finger FYVE domain-containing protein 9 isoform 1
ZFYVE9/iso:1
"A zinc finger FYVE domain-containing protein 9 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95405-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]

organism-sequence


PR:A2A8R0
zinc finger FYVE domain-containing protein 9 isoform 1 (mouse)
mZFYVE9/iso:1
"A zinc finger FYVE domain-containing protein 9 isoform 1 that is encoded in the genome of mouse." [PRO:DAN]

organism-sequence


PR:O95405-1
zinc finger FYVE domain-containing protein 9 isoform 1 (human)
hZFYVE9/iso:1
"A zinc finger FYVE domain-containing protein 9 isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
modification


PR:000002535
zinc finger FYVE domain-containing protein 9 isoform 1 unmodified form
ZFYVE9/iso:1/UnMod
"A zinc finger FYVE domain-containing protein 9 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]

sequence


PR:000000314
zinc finger FYVE domain-containing protein 9 isoform 2
ZFYVE9/iso:2
"A zinc finger FYVE domain-containing protein 9 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95405-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]

organism-sequence


PR:A8Y5G5
zinc finger FYVE domain-containing protein 9 isoform 2 (mouse)
mZFYVE9/iso:2
"A zinc finger FYVE domain-containing protein 9 isoform 2 that is encoded in the genome of mouse." [PRO:DAN]

organism-sequence


PR:O95405-2
zinc finger FYVE domain-containing protein 9 isoform 2 (human)
hZFYVE9/iso:2
"A zinc finger FYVE domain-containing protein 9 isoform 2 that is encoded in the genome of human." [PRO:CNA]
Yes
sequence


PR:000000315
zinc finger FYVE domain-containing protein 9 isoform 3
ZFYVE9/iso:3
"A zinc finger FYVE domain-containing protein 9 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95405-3 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]

organism-sequence


PR:O95405-3
zinc finger FYVE domain-containing protein 9 isoform 3 (human)
hZFYVE9/iso:3
"A zinc finger FYVE domain-containing protein 9 isoform 3 that is encoded in the genome of human." [PRO:CNA]
Yes
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ZFYVE9 forms found in complexes   

ZFYVE9 Component
 Complexes
PR:000000125 ZFYVE9 PR:000025974 TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex
PR:O95405 hZFYVE9 PR:000025965 TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006897 endocytosisPR:O95405-1 hZFYVE9/iso:1 PMID:12809483
GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathwayPR:000000125 ZFYVE9 PANTHER:PTHR22835
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:O95405-1 hZFYVE9/iso:1 PMID:10615055
GO:0060390 regulation of SMAD protein signal transductionPR:O95405-1 hZFYVE9/iso:1 PMID:11877415; PMID:12356868
GO:0060395 SMAD protein signal transductionPR:O95405-1 hZFYVE9/iso:1 PMID:11877415; PMID:12356868

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005515 protein bindingPR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260
PR:O95405-1 hZFYVE9/iso:1 PMID:17693260

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615 extracellular spacePR:O95405-2 hZFYVE9/iso:2 PMID:9582421
PR:O95405-3 hZFYVE9/iso:3 PMID:9582421
GO:0005769 early endosomePR:O95405-1 hZFYVE9/iso:1 PMID:11877415; PMID:12356868; PMID:12432064