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Protein Ontology report - thrombospondin-1
PR:000000129 - http://purl.obolibrary.org/obo/PR_000000129
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000129   
  PRO namethrombospondin-1 
  Synonyms
PRO-Short-label: EXACT:THBS1
Gene-based: RELATED:TSP | TSP1
Other: EXACT:glycoprotein G
  Definition"A thrombospondin subgroup A that is a translation product of the human THBS1 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000029 thrombospondin subgroup A
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification7                                                  Organism-Modification 21                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000129
thrombospondin-1
THBS1
"A thrombospondin subgroup A that is a translation product of the human THBS1 gene or a 1:1 ortholog thereof." [PRO:CNA]
Yes
organism-gene


PR:P07996
thrombospondin-1 (human)
hTHBS1
"A thrombospondin-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P07996]

organism-sequence


PR:P07996-1
thrombospondin-1 isoform 1 (human)
hTHBS1/iso:1
"A thrombospondin-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000026338
thrombospondin-1 isoform 1, signal peptide removed form (human)
hTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in human. UniProtKB:P07996-1, 19-1170." [PRO:DNx, UniProtKB:P07996]
Yes
organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000028966
thrombospondin-1 isoform 1 cleaved 2 (human)
hTHBS1/iso:1/Clv:2
"A thrombospondin-1 isoform 1 cleaved 2 in human. UniProtKB:P07996-1, 19-311." [PRO:DAN]

organism-sequence


PR:P07996-2
thrombospondin-1 isoform 2 (human)
hTHBS1/iso:2
"A thrombospondin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07996-2." [PRO:DNx, UniProtKB:P07996]

organism-modification


PR:000028410
thrombospondin-1, signal peptide removed form (human)
hTHBS1/SigPep-
"A thrombospondin-1, signal peptide removed form in human. Example: UniProtKB:P07996-1, 19-1170." [PRO:DNx]
Yes
Yes
organism-modification


PR:000026338
thrombospondin-1 isoform 1, signal peptide removed form (human)
hTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in human. UniProtKB:P07996-1, 19-1170." [PRO:DNx, UniProtKB:P07996]
Yes
organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000064777
thrombospondin-1, signal peptide removed O-glycosylserine form (human)
hTHBS1/SigPep-/OGlycoSer+
"A thrombospondin-1 (human) that has had the signal peptide removed and that includes at least one O-glycosylated serine. Example: UniProtKB:P07996-1, 19-1170, MOD:00002." [PRO:DNx, Reactome:R-HSA-5172997]

organism-modification


PR:000060409
thrombospondin-1, signal peptide removed fucosylserine form (human)
hTHBS1/SigPep-/FucSer+
"A thrombospondin-1 (human) that has had the signal peptide removed and that includes at least one fucosylserine. Example: UniProtKB:P07996-1, 19-1170, MOD:00812." [PRO:DNx, Reactome:R-HSA-5173278]

organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000054414
thrombospondin-1 N-glycosylated 1 (human)
hTHBS1/NGlyco:1
"A thrombospondin-1 (human) that has been N-glycosylated at the residue equivalent to Asn-1067 of the amino acid sequence represented by UniProtKB:P07996-1, in which the glycan composition is represented by GlyTouCan:G09197ZW. Example: UniProtKB:P07996-1, Asn-1067, MOD:00160~GNO:G09197ZW." [GlyGen:P07996-1, PMID:29741879, PRO:DNx]

organism-modification


PR:000054415
thrombospondin-1 N-glycosylated 2 (human)
hTHBS1/NGlyco:2
"A thrombospondin-1 (human) that has been N-glycosylated at the residue equivalent to Asn-1067 of the amino acid sequence represented by UniProtKB:P07996-1, in which the glycan composition is represented by GlyTouCan:G16175ZV. Example: UniProtKB:P07996-1, Asn-1067, MOD:00160~GNO:G16175ZV." [GlyGen:P07996-1, PMID:29741879, PRO:DNx]

organism-modification


PR:000054416
thrombospondin-1 N-glycosylated 3 (human)
hTHBS1/NGlyco:3
"A thrombospondin-1 (human) that has been N-glycosylated at the residue equivalent to Asn-1067 of the amino acid sequence represented by UniProtKB:P07996-1, in which the glycan composition is represented by GlyTouCan:G27126ED. Example: UniProtKB:P07996-1, Asn-1067, MOD:00160~GNO:G27126ED." [GlyGen:P07996-1, PMID:29741879, PRO:DNx]

organism-modification


PR:000054418
thrombospondin-1 N-glycosylated 5 (human)
hTHBS1/NGlyco:5
"A thrombospondin-1 (human) that has been N-glycosylated at the residue equivalent to Asn-1067 of the amino acid sequence represented by UniProtKB:P07996-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P07996-1, Asn-1067, MOD:00160~GNO:G59626AS." [GlyGen:P07996-1, PMID:23345538, PMID:29671580, PRO:DNx]

organism-modification


PR:000054419
thrombospondin-1 N-glycosylated 6 (human)
hTHBS1/NGlyco:6
"A thrombospondin-1 (human) that has been N-glycosylated at the residue equivalent to Asn-360 of the amino acid sequence represented by UniProtKB:P07996-1, in which the glycan composition is represented by GlyTouCan:G87051GH. Example: UniProtKB:P07996-1, Asn-360, MOD:00160~GNO:G87051GH." [GlyGen:P07996-1, PMID:29741879, PRO:DNx]

organism-modification


PR:000060409
thrombospondin-1, signal peptide removed fucosylserine form (human)
hTHBS1/SigPep-/FucSer+
"A thrombospondin-1 (human) that has had the signal peptide removed and that includes at least one fucosylserine. Example: UniProtKB:P07996-1, 19-1170, MOD:00812." [PRO:DNx, Reactome:R-HSA-5173278]

organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000064777
thrombospondin-1, signal peptide removed O-glycosylserine form (human)
hTHBS1/SigPep-/OGlycoSer+
"A thrombospondin-1 (human) that has had the signal peptide removed and that includes at least one O-glycosylated serine. Example: UniProtKB:P07996-1, 19-1170, MOD:00002." [PRO:DNx, Reactome:R-HSA-5172997]

organism-modification


PR:000060409
thrombospondin-1, signal peptide removed fucosylserine form (human)
hTHBS1/SigPep-/FucSer+
"A thrombospondin-1 (human) that has had the signal peptide removed and that includes at least one fucosylserine. Example: UniProtKB:P07996-1, 19-1170, MOD:00812." [PRO:DNx, Reactome:R-HSA-5173278]

organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000073784
thrombospondin-1 methylated 1 (human)
hTHBS1/Me:1
"A thrombospondin-1 (human) that has been methylated on the residue at the position equivalent to Cys-270 of the amino acid sequence represented by UniProtKB:P07996-1. Example: UniProtKB:P07996-1, Cys-270, MOD:00660." [IEDB_epitope:1023271, PRO:DNx]

organism-modification


PR:000076437
thrombospondin-1 deaminated 1 (human)
hTHBS1/Deam:1
"A thrombospondin-1 (human) that has been deaminated on the residue at the position equivalent to Gln-209 of the amino acid sequence represented by UniProtKB:P07996-1. Example: UniProtKB:P07996-1, Gln-209, MOD:00685." [IEDB_epitope:1999117, PRO:DNx]

organism-modification


PR:000079618
thrombospondin-1 cysteinylated 1 (human)
hTHBS1/Cyst:1
"A thrombospondin-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-874 of the amino acid sequence represented by UniProtKB:P07996-1. Example: UniProtKB:P07996-1, Cys-874, MOD:00765." [IEDB_epitope:1562937, PRO:DNx]

organism-modification


PR:000079709
thrombospondin-1 cysteinylated 2 (human)
hTHBS1/Cyst:2
"A thrombospondin-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-754 of the amino acid sequence represented by UniProtKB:P07996-1. Example: UniProtKB:P07996-1, Cys-754, MOD:00765." [IEDB_epitope:1562921, IEDB_epitope:1581350, PRO:DNx]

organism-gene


PR:P35441
thrombospondin-1 (mouse)
mTHBS1
"A thrombospondin-1 that is encoded in the genome of mouse." [OMA:P35441, PRO:DNx]

organism-sequence


PR:P35441-1
thrombospondin-1 isoform 1 (mouse)
mTHBS1/iso:1
"A thrombospondin-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

organism-modification


PR:000036485
thrombospondin-1 isoform 1, signal peptide removed form (mouse)
mTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in mouse. UniProtKB:P35441-1, 19-1170." [PMID:12498716, PRO:CNA]
Yes
organism-modification


PR:000036487
thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
mTHBS1/iso:1/SigPep-/GlycoRes+
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form in mouse. UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813." [PMID:1459996, PMID:9657149, PRO:CNA]
Yes
organism-modification


PR:000036490
thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in mouse. UniProtKB:P35441-1, 312-1170, MOD:00693." [PMID:17082774, PRO:CNA]
Yes
organism-modification


PR:000036486
thrombospondin-1 isoform 1 cleaved 2 (mouse)
mTHBS1/iso:1/Clv:2
"A thrombospondin-1 isoform 1 cleaved 2 in mouse. UniProtKB:P35441-1, 19-311." [PMID:17082774, PRO:CNA]
Yes
organism-modification


PR:000044495
thrombospondin-1, signal peptide removed form (mouse)
mTHBS1/SigPep-
"A thrombospondin-1, signal peptide removed form in mouse. UniProtKB:P35441, 19-1170." [PMID:12498716, PMID:8654563, PRO:CNA]
Yes
organism-modification


PR:000036485
thrombospondin-1 isoform 1, signal peptide removed form (mouse)
mTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in mouse. UniProtKB:P35441-1, 19-1170." [PMID:12498716, PRO:CNA]
Yes
organism-modification


PR:000036487
thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
mTHBS1/iso:1/SigPep-/GlycoRes+
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form in mouse. UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813." [PMID:1459996, PMID:9657149, PRO:CNA]
Yes
organism-modification


PR:000036490
thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in mouse. UniProtKB:P35441-1, 312-1170, MOD:00693." [PMID:17082774, PRO:CNA]
Yes
sequence


PR:000000376
thrombospondin-1 isoform 1
THBS1/iso:1
"A thrombospondin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07996-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]

organism-sequence


PR:P07996-1
thrombospondin-1 isoform 1 (human)
hTHBS1/iso:1
"A thrombospondin-1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000026338
thrombospondin-1 isoform 1, signal peptide removed form (human)
hTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in human. UniProtKB:P07996-1, 19-1170." [PRO:DNx, UniProtKB:P07996]
Yes
organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000028966
thrombospondin-1 isoform 1 cleaved 2 (human)
hTHBS1/iso:1/Clv:2
"A thrombospondin-1 isoform 1 cleaved 2 in human. UniProtKB:P07996-1, 19-311." [PRO:DAN]

organism-sequence


PR:P35441-1
thrombospondin-1 isoform 1 (mouse)
mTHBS1/iso:1
"A thrombospondin-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

organism-modification


PR:000036485
thrombospondin-1 isoform 1, signal peptide removed form (mouse)
mTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in mouse. UniProtKB:P35441-1, 19-1170." [PMID:12498716, PRO:CNA]
Yes
organism-modification


PR:000036487
thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
mTHBS1/iso:1/SigPep-/GlycoRes+
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form in mouse. UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813." [PMID:1459996, PMID:9657149, PRO:CNA]
Yes
organism-modification


PR:000036490
thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in mouse. UniProtKB:P35441-1, 312-1170, MOD:00693." [PMID:17082774, PRO:CNA]
Yes
organism-modification


PR:000036486
thrombospondin-1 isoform 1 cleaved 2 (mouse)
mTHBS1/iso:1/Clv:2
"A thrombospondin-1 isoform 1 cleaved 2 in mouse. UniProtKB:P35441-1, 19-311." [PMID:17082774, PRO:CNA]
Yes
modification


PR:000000587
thrombospondin-1 isoform 1, signal peptide removed form
THBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1 that has had the signal peptide removed." [PRO:CNA]

modification


PR:000000485
thrombospondin-1 isoform 1 cleaved and glycosylated form
THBS1/iso:1/ClvGlyco+
"A thrombospondin-1 isoform 1, signal peptide removed form that has been processed by proteolytic cleavage and includes at least one glycosylated residue." [PRO:CNA]

modification


PR:000000590
thrombospondin-1 isoform 1 cleaved 2 glycosylated form
THBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved and glycosylated form that has been proteolytically processed by ADAMTS1 to render a C-terminal domain product." [PMID:17082774]

organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000036490
thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in mouse. UniProtKB:P35441-1, 312-1170, MOD:00693." [PMID:17082774, PRO:CNA]
Yes
modification


PR:000000589
thrombospondin-1 isoform 1, signal peptide removed glycosylated form
THBS1/iso:1/SigPep-/GlycoRes+
"A thrombospondin-1 isoform 1, signal peptide removed form that has been post-translationally modified to include C-mannosylation on WxxW patterns, and O-fucosylation in CSx[ST]CG motif." [PMID:11067851, PRO:CNA]

organism-modification


PR:000036487
thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
mTHBS1/iso:1/SigPep-/GlycoRes+
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form in mouse. UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813." [PMID:1459996, PMID:9657149, PRO:CNA]
Yes
organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000026338
thrombospondin-1 isoform 1, signal peptide removed form (human)
hTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in human. UniProtKB:P07996-1, 19-1170." [PRO:DNx, UniProtKB:P07996]
Yes
organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000036485
thrombospondin-1 isoform 1, signal peptide removed form (mouse)
mTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in mouse. UniProtKB:P35441-1, 19-1170." [PMID:12498716, PRO:CNA]
Yes
organism-modification


PR:000036487
thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
mTHBS1/iso:1/SigPep-/GlycoRes+
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form in mouse. UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813." [PMID:1459996, PMID:9657149, PRO:CNA]
Yes
organism-modification


PR:000036490
thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in mouse. UniProtKB:P35441-1, 312-1170, MOD:00693." [PMID:17082774, PRO:CNA]
Yes
modification


PR:000000588
thrombospondin-1 isoform 1 cleaved 2
THBS1/iso:1/Clv:2
"A thrombospondin-1 isoform 1 that has been proteolytically processed by ADAMTS1 to render an N-terminal domain product." [PMID:17082774]

organism-modification


PR:000028966
thrombospondin-1 isoform 1 cleaved 2 (human)
hTHBS1/iso:1/Clv:2
"A thrombospondin-1 isoform 1 cleaved 2 in human. UniProtKB:P07996-1, 19-311." [PRO:DAN]

organism-modification


PR:000036486
thrombospondin-1 isoform 1 cleaved 2 (mouse)
mTHBS1/iso:1/Clv:2
"A thrombospondin-1 isoform 1 cleaved 2 in mouse. UniProtKB:P35441-1, 19-311." [PMID:17082774, PRO:CNA]
Yes
modification


PR:000018282
thrombospondin-1, signal peptide removed form
THBS1/SigPep-
"A thrombospondin-1 that has had the signal peptide removed." [PRO:DNx]

modification


PR:000000587
thrombospondin-1 isoform 1, signal peptide removed form
THBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1 that has had the signal peptide removed." [PRO:CNA]

modification


PR:000000485
thrombospondin-1 isoform 1 cleaved and glycosylated form
THBS1/iso:1/ClvGlyco+
"A thrombospondin-1 isoform 1, signal peptide removed form that has been processed by proteolytic cleavage and includes at least one glycosylated residue." [PRO:CNA]

modification


PR:000000590
thrombospondin-1 isoform 1 cleaved 2 glycosylated form
THBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved and glycosylated form that has been proteolytically processed by ADAMTS1 to render a C-terminal domain product." [PMID:17082774]

organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000036490
thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in mouse. UniProtKB:P35441-1, 312-1170, MOD:00693." [PMID:17082774, PRO:CNA]
Yes
modification


PR:000000589
thrombospondin-1 isoform 1, signal peptide removed glycosylated form
THBS1/iso:1/SigPep-/GlycoRes+
"A thrombospondin-1 isoform 1, signal peptide removed form that has been post-translationally modified to include C-mannosylation on WxxW patterns, and O-fucosylation in CSx[ST]CG motif." [PMID:11067851, PRO:CNA]

organism-modification


PR:000036487
thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
mTHBS1/iso:1/SigPep-/GlycoRes+
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form in mouse. UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813." [PMID:1459996, PMID:9657149, PRO:CNA]
Yes
organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000026338
thrombospondin-1 isoform 1, signal peptide removed form (human)
hTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in human. UniProtKB:P07996-1, 19-1170." [PRO:DNx, UniProtKB:P07996]
Yes
organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000036485
thrombospondin-1 isoform 1, signal peptide removed form (mouse)
mTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in mouse. UniProtKB:P35441-1, 19-1170." [PMID:12498716, PRO:CNA]
Yes
organism-modification


PR:000036487
thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
mTHBS1/iso:1/SigPep-/GlycoRes+
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form in mouse. UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813." [PMID:1459996, PMID:9657149, PRO:CNA]
Yes
organism-modification


PR:000036490
thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in mouse. UniProtKB:P35441-1, 312-1170, MOD:00693." [PMID:17082774, PRO:CNA]
Yes
organism-modification


PR:000028410
thrombospondin-1, signal peptide removed form (human)
hTHBS1/SigPep-
"A thrombospondin-1, signal peptide removed form in human. Example: UniProtKB:P07996-1, 19-1170." [PRO:DNx]
Yes
Yes
organism-modification


PR:000026338
thrombospondin-1 isoform 1, signal peptide removed form (human)
hTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in human. UniProtKB:P07996-1, 19-1170." [PRO:DNx, UniProtKB:P07996]
Yes
organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000064777
thrombospondin-1, signal peptide removed O-glycosylserine form (human)
hTHBS1/SigPep-/OGlycoSer+
"A thrombospondin-1 (human) that has had the signal peptide removed and that includes at least one O-glycosylated serine. Example: UniProtKB:P07996-1, 19-1170, MOD:00002." [PRO:DNx, Reactome:R-HSA-5172997]

organism-modification


PR:000060409
thrombospondin-1, signal peptide removed fucosylserine form (human)
hTHBS1/SigPep-/FucSer+
"A thrombospondin-1 (human) that has had the signal peptide removed and that includes at least one fucosylserine. Example: UniProtKB:P07996-1, 19-1170, MOD:00812." [PRO:DNx, Reactome:R-HSA-5173278]

organism-modification


PR:000036488
thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]
Yes
organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000044495
thrombospondin-1, signal peptide removed form (mouse)
mTHBS1/SigPep-
"A thrombospondin-1, signal peptide removed form in mouse. UniProtKB:P35441, 19-1170." [PMID:12498716, PMID:8654563, PRO:CNA]
Yes
organism-modification


PR:000036485
thrombospondin-1 isoform 1, signal peptide removed form (mouse)
mTHBS1/iso:1/SigPep-
"A thrombospondin-1 isoform 1, signal peptide removed form in mouse. UniProtKB:P35441-1, 19-1170." [PMID:12498716, PRO:CNA]
Yes
organism-modification


PR:000036487
thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
mTHBS1/iso:1/SigPep-/GlycoRes+
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form in mouse. UniProtKB:P35441-1, 19-1170, MOD:00222|MOD:00812|MOD:00813." [PMID:1459996, PMID:9657149, PRO:CNA]
Yes
organism-modification


PR:000036490
thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in mouse. UniProtKB:P35441-1, 312-1170, MOD:00693." [PMID:17082774, PRO:CNA]
Yes
modification


PR:000025437
thrombospondin-1 proteolytic cleavage product
THBS1/ClvPrd
"A thrombospondin-1 that has been processed by proteolytic cleavage." [PRO:DNx]

modification


PR:000000485
thrombospondin-1 isoform 1 cleaved and glycosylated form
THBS1/iso:1/ClvGlyco+
"A thrombospondin-1 isoform 1, signal peptide removed form that has been processed by proteolytic cleavage and includes at least one glycosylated residue." [PRO:CNA]

modification


PR:000000590
thrombospondin-1 isoform 1 cleaved 2 glycosylated form
THBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved and glycosylated form that has been proteolytically processed by ADAMTS1 to render a C-terminal domain product." [PMID:17082774]

organism-modification


PR:000036489
thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in human and that has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 312-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PRO:CNA]

organism-modification


PR:000036490
thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
"A thrombospondin-1 isoform 1 cleaved 2 glycosylated form in mouse. UniProtKB:P35441-1, 312-1170, MOD:00693." [PMID:17082774, PRO:CNA]
Yes
modification


PR:000000588
thrombospondin-1 isoform 1 cleaved 2
THBS1/iso:1/Clv:2
"A thrombospondin-1 isoform 1 that has been proteolytically processed by ADAMTS1 to render an N-terminal domain product." [PMID:17082774]

organism-modification


PR:000028966
thrombospondin-1 isoform 1 cleaved 2 (human)
hTHBS1/iso:1/Clv:2
"A thrombospondin-1 isoform 1 cleaved 2 in human. UniProtKB:P07996-1, 19-311." [PRO:DAN]

organism-modification


PR:000036486
thrombospondin-1 isoform 1 cleaved 2 (mouse)
mTHBS1/iso:1/Clv:2
"A thrombospondin-1 isoform 1 cleaved 2 in mouse. UniProtKB:P35441-1, 19-311." [PMID:17082774, PRO:CNA]
Yes
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THBS1 forms found in complexes   

THBS1 Component
 Complexes
PR:000028410 hTHBS1/SigPep- PR:000028445 integrin alphaIIbbeta3:thrombospondin 1 (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007596 blood coagulationPR:000000129 THBS1 PANTHER:PTHR10199
GO:0016525 negative regulation of angiogenesisPR:000036486 mTHBS1/iso:1/Clv:2 PMID:17082774
PR:000036490 mTHBS1/iso:1/Clv:2/GlycoRes+ PMID:17082774
GO:0060055 angiogenesis involved in wound healingPR:000036486 mTHBS1/iso:1/Clv:2 PMID:17082774
PR:000036490 mTHBS1/iso:1/Clv:2/GlycoRes+ PMID:17082774

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0004866 endopeptidase inhibitor activityPR:000026338 hTHBS1/iso:1/SigPep- PMID:8751720
GO:0005515 protein bindingPR:000036487 mTHBS1/iso:1/SigPep-/GlycoRes+ PMID:1459996
PR:000036488 hTHBS1/iso:1/SigPep-/Glyco:1 PMID:3305519
GO:0042802 identical protein bindingPR:000036486 mTHBS1/iso:1/Clv:2 PMID:17082774
GO:0050431 transforming growth factor beta bindingPR:000036487 mTHBS1/iso:1/SigPep-/GlycoRes+ PMID:9657149
PR:000036488 hTHBS1/iso:1/SigPep-/Glyco:1 PMID:15342643

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615 extracellular spacePR:000026338 hTHBS1/iso:1/SigPep- PMID:15662972
PR:000028410 hTHBS1/SigPep- PMID:15662972
PR:000036485 mTHBS1/iso:1/SigPep- PMID:12498716
PR:000036487 mTHBS1/iso:1/SigPep-/GlycoRes+ PMID:9657149
PR:000044495 mTHBS1/SigPep- PMID:12498716