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Protein Ontology report - bone morphogenetic protein 2
PR:000000164 - http://purl.obolibrary.org/obo/PR_000000164
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000164   
  PRO namebone morphogenetic protein 2 
  Synonyms
PRO-Short-label: EXACT:BMP2
Gene-based: RELATED:BMP2A
Other: EXACT:BMP-2 | BMP-2A | bone morphogenetic protein 2A
  Definition"A bone morphogenetic protein that is a translation product of the human BMP2 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000034 bone morphogenetic protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000164 bone morphogenetic protein 2
BMP2
Yes
organism-gene


PR:P12643 bone morphogenetic protein 2 (human)
hBMP2

organism-sequence


PR:P12643-1 bone morphogenetic protein 2 isoform 1 (human)
hBMP2/iso:1
Yes
organism-modification


PR:000026336 bone morphogenetic protein 2 isoform 1, mature form (human)
hBMP2/iso:1/mature
Yes
organism-modification


PR:000046491 bone morphogenetic protein 2, signal peptide removed form (human)
hBMP2/SigPep-

organism-modification


PR:000026336 bone morphogenetic protein 2 isoform 1, mature form (human)
hBMP2/iso:1/mature
Yes
organism-gene


PR:P21274 bone morphogenetic protein 2 (mouse)
mBMP2

organism-sequence


PR:000050190 bone morphogenetic protein 2 isoform m2 (mouse)
mBMP2/iso:m2

organism-sequence


PR:P21274-1 bone morphogenetic protein 2 isoform 1 (mouse)
mBMP2/iso:1
Yes
organism-modification


PR:000036510 bone morphogenetic protein 2 isoform 1, mature form (mouse)
mBMP2/iso:1/mature
Yes
organism-gene


PR:P49001 bone morphogenetic protein 2 (rat)
rBMP2

sequence


PR:000000385 bone morphogenetic protein 2 isoform 1
BMP2/iso:1

organism-sequence


PR:P12643-1 bone morphogenetic protein 2 isoform 1 (human)
hBMP2/iso:1
Yes
organism-modification


PR:000026336 bone morphogenetic protein 2 isoform 1, mature form (human)
hBMP2/iso:1/mature
Yes
organism-sequence


PR:P21274-1 bone morphogenetic protein 2 isoform 1 (mouse)
mBMP2/iso:1
Yes
organism-modification


PR:000036510 bone morphogenetic protein 2 isoform 1, mature form (mouse)
mBMP2/iso:1/mature
Yes
modification


PR:000000608 bone morphogenetic protein 2 isoform 1, mature form
BMP2/iso:1/mature

organism-modification


PR:000026336 bone morphogenetic protein 2 isoform 1, mature form (human)
hBMP2/iso:1/mature
Yes
organism-modification


PR:000036510 bone morphogenetic protein 2 isoform 1, mature form (mouse)
mBMP2/iso:1/mature
Yes
modification


PR:000021898 bone morphogenetic protein 2 isoform 1, signal peptide removed form
BMP2/iso:1/SigPep-

modification


PR:000000608 bone morphogenetic protein 2 isoform 1, mature form
BMP2/iso:1/mature

organism-modification


PR:000026336 bone morphogenetic protein 2 isoform 1, mature form (human)
hBMP2/iso:1/mature
Yes
organism-modification


PR:000036510 bone morphogenetic protein 2 isoform 1, mature form (mouse)
mBMP2/iso:1/mature
Yes
modification


PR:000018286 bone morphogenetic protein 2 proteolytic cleavage product
BMP2/ClvPrd

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000164 BMP2 acts_upstream_of_or_withinGO:0001501 skeletal system development PANTHER:PTHR11848
GO:0007267 cell-cell signaling PANTHER:PTHR11848
GO:0030509 BMP signaling pathway PANTHER:PTHR11848
PR:000026336 hBMP2/iso:1/mature
UniProtKB:P12643-1, 283-396		 acts_upstream_of_or_withinGO:0001501 skeletal system development PMID:2315314
GO:0007267 cell-cell signaling PMID:2315314
enablesGO:0005102 signaling receptor binding PMID:2315314
GO:0042803 protein homodimerization activity PMID:10074410
located_inGO:0005615 extracellular space PMID:2315314
PR:000036510 mBMP2/iso:1/mature
UniProtKB:P21274-1, 281-394		 acts_upstream_of_or_withinGO:0001501 skeletal system development PMID:15565649; PMID:16109715
GO:0030509 BMP signaling pathway PMID:14623234
located_inGO:0005615 extracellular space PMID:15110716
PR:P12643-1 hBMP2/iso:1 acts_upstream_of_or_withinGO:0001501 skeletal system development PMID:2315314
GO:0007267 cell-cell signaling PMID:2315314
PR:P21274-1 mBMP2/iso:1 acts_upstream_of_or_withinGO:0030509 BMP signaling pathway PMID:14623234