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Protein Ontology report - TGF-beta receptor type-1 isoform 1
PR:000000185 - http://purl.obolibrary.org/obo/PR_000000185
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000185   
  PRO nameTGF-beta receptor type-1 isoform 1 
  Synonyms
PRO-Short-label: EXACT:TGFBR1/iso:1
  Definition"A TGF-beta receptor type-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36897-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000047 TGF-beta receptor type-1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification4                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000185 TGF-beta receptor type-1 isoform 1
TGFBR1/iso:1

organism-sequence


PR:P36897-1 TGF-beta receptor type-1 isoform 1 (human)
hTGFBR1/iso:1
Yes
organism-modification


PR:000036432 TGF-beta receptor type-1 isoform 1, signal peptide removed form (human)
hTGFBR1/iso:1/SigPep-
Yes
organism-modification


PR:000025959 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human)
hTGFBR1/iso:1/SigPep-/Phos:1
Yes
Yes
organism-sequence


PR:Q64729-1 TGF-beta receptor type-1 isoform 1 (mouse)
mTGFBR1/iso:1

organism-modification


PR:000036434 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (mouse)
mTGFBR1/iso:1/SigPep-/Phos:1
Yes
modification


PR:000000522 TGF-beta receptor type-1 isoform 1, signal peptide removed form
TGFBR1/iso:1/SigPep-

modification


PR:000000408 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated form
TGFBR1/iso:1/SigPep-/PhosRes+

modification


PR:000000523 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1
TGFBR1/iso:1/SigPep-/Phos:1

Yes
organism-modification


PR:000025959 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human)
hTGFBR1/iso:1/SigPep-/Phos:1
Yes
Yes
organism-modification


PR:000036434 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (mouse)
mTGFBR1/iso:1/SigPep-/Phos:1
Yes
modification


PR:000003173 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated and ubiquitinated form
TGFBR1/iso:1/SigPep-/PhosUbiq+

modification


PR:000003173 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated and ubiquitinated form
TGFBR1/iso:1/SigPep-/PhosUbiq+

organism-modification


PR:000036432 TGF-beta receptor type-1 isoform 1, signal peptide removed form (human)
hTGFBR1/iso:1/SigPep-
Yes
organism-modification


PR:000025959 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human)
hTGFBR1/iso:1/SigPep-/Phos:1
Yes
Yes
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TGFBR1/iso:1 forms found in complexes   

TGFBR1/iso:1 Component
 Complexes
PR:000000523 TGFBR1/iso:1/SigPep-/Phos:1 PR:000025975 transforming growth factor beta type I receptor homodimeric complex phosphorylated form
PR:000025959 hTGFBR1/iso:1/SigPep-/Phos:1 PR:000025961 transforming growth factor beta type I receptor homodimeric complex phosphorylated form (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025959 hTGFBR1/iso:1/SigPep-/Phos:1
UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047		 acts_upstream_of_or_withinGO:0006468 protein phosphorylation PMID:7774578
GO:0007165 signal transduction PMID:8242743
GO:0007181 transforming growth factor beta receptor complex assembly PMID:8947046
enablesGO:0005025 transforming growth factor beta receptor activity, type I PMID:7774578; PMID:8947046
located_inGO:0005886 plasma membrane PMID:8947046
PR:000036432 hTGFBR1/iso:1/SigPep-
UniProtKB:P36897-1, 34-503		 acts_upstream_of_or_withinGO:0007165 signal transduction PMID:8242743
GO:0007181 transforming growth factor beta receptor complex assembly PMID:8242743
located_inGO:0005886 plasma membrane PMID:8242743
PR:000036434 mTGFBR1/iso:1/SigPep-/Phos:1
UniProtKB:Q64729-1, 23-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047		 acts_upstream_of_or_withinGO:0006468 protein phosphorylation PMID:12065756
PR:P36897-1 hTGFBR1/iso:1 acts_upstream_of_or_withinGO:0007165 signal transduction PMID:8242743