back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - activin/inhibin beta A chain
PR:000000216 - http://purl.obolibrary.org/obo/PR_000000216
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000216   
  PRO nameactivin/inhibin beta A chain 
  Synonyms
PRO-Short-label: EXACT:INHBA
Other: EXACT:activin beta-A chain | EDF | erythroid differentiation protein
  Definition"An activin/inhibin beta subunit that is a translation product of the human INHBA gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000072 activin/inhibin beta subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000000216

activin/inhibin beta A chain

INHBA


"An activin/inhibin beta subunit that is a translation product of the human INHBA gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P08476

inhibin beta A chain (human)

hINHBA


"An activin/inhibin beta A chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P08476]


organism-sequence



PR:P08476-1

inhibin beta A chain isoform 1 (human)

hINHBA/iso:1


"An activin/inhibin beta A chain isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036540

activin/inhibin beta A chain isoform 1 mature form (human)

hINHBA/iso:1/mature


"An activin/inhibin beta A chain isoform 1 mature form in human. UniProtKB:P08476-1, 311-426." [PMID:10320815, PMID:12213882, PMID:12456957, PMID:12960042, PMID:1537316, PMID:17456790, PMID:2575216, PMID:7890768, PMID:9884026, PRO:CNA]

Yes

organism-modification



PR:000054446

inhibin beta A chain O-glycosylated 1 (human)

hINHBA/OGlyco:1


"An inhibin beta A chain (human) that has been O-glycosylated at the residue equivalent to Ser-30 of the amino acid sequence represented by UniProtKB:P08476-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P08476-1, Ser-30, MOD:00002~GNO:G43417UB." [GlyGen:P08476-1, PMID:30459171, PRO:DNx]


organism-gene



PR:P18331

inhibin beta A chain (rat)

rINHBA


"An activin/inhibin beta A chain that is encoded in the genome of rat." [OMA:P18331, PRO:DNx]


organism-gene



PR:P27092

inhibin beta A chain (chicken)

chick-INHBA


"An activin/inhibin beta A chain that is encoded in the genome of chicken." [OMA:P27092, PRO:DNx]


organism-gene



PR:Q04998

inhibin beta A chain (mouse)

mINHBA


"An activin/inhibin beta A chain that is encoded in the genome of mouse." [OMA:Q04998, PRO:DNx]


organism-sequence



PR:Q04998-1

inhibin beta A chain isoform 1 (mouse)

mINHBA/iso:1


"An activin/inhibin beta A chain isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-modification



PR:000036539

activin/inhibin beta A chain isoform 1 mature form (mouse)

mINHBA/iso:1/mature


"An activin/inhibin beta A chain isoform 1 mature form in mouse. UniProtKB:Q04998-1, 309-424." [PMID:1646080, PMID:2133547, PMID:7577669, PRO:CNA]

Yes

sequence



PR:000000416

activin/inhibin beta A chain isoform 1

INHBA/iso:1


"An activin/inhibin beta A chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08476-1 or a 1:1 ortholog thereof." [PMID:15319829, PRO:CNA, PRO:DAN]


organism-sequence



PR:P08476-1

inhibin beta A chain isoform 1 (human)

hINHBA/iso:1


"An activin/inhibin beta A chain isoform 1 that is encoded in the genome of human." [PRO:CNA]

Yes

organism-modification



PR:000036540

activin/inhibin beta A chain isoform 1 mature form (human)

hINHBA/iso:1/mature


"An activin/inhibin beta A chain isoform 1 mature form in human. UniProtKB:P08476-1, 311-426." [PMID:10320815, PMID:12213882, PMID:12456957, PMID:12960042, PMID:1537316, PMID:17456790, PMID:2575216, PMID:7890768, PMID:9884026, PRO:CNA]

Yes

organism-sequence



PR:Q04998-1

inhibin beta A chain isoform 1 (mouse)

mINHBA/iso:1


"An activin/inhibin beta A chain isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-modification



PR:000036539

activin/inhibin beta A chain isoform 1 mature form (mouse)

mINHBA/iso:1/mature


"An activin/inhibin beta A chain isoform 1 mature form in mouse. UniProtKB:Q04998-1, 309-424." [PMID:1646080, PMID:2133547, PMID:7577669, PRO:CNA]

Yes

modification



PR:000021911

activin/inhibin beta A chain isoform 1, signal peptide removed form

INHBA/iso:1/SigPep-


"An activin/inhibin beta A chain isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000637

activin/inhibin beta A chain isoform 1 mature form

INHBA/iso:1/mature


"An activin/inhibin beta A chain isoform 1, signal peptide removed form that has been processed by subsequent removal of the propeptide. It is a subunit of inhibin A and activin A complexes. Inhibin A complex is a dimer of INHA and INHBA, whereas activin A complex is a homodimer of INHBA." [PMID:15948132]


organism-modification



PR:000036539

activin/inhibin beta A chain isoform 1 mature form (mouse)

mINHBA/iso:1/mature


"An activin/inhibin beta A chain isoform 1 mature form in mouse. UniProtKB:Q04998-1, 309-424." [PMID:1646080, PMID:2133547, PMID:7577669, PRO:CNA]

Yes

organism-modification



PR:000036540

activin/inhibin beta A chain isoform 1 mature form (human)

hINHBA/iso:1/mature


"An activin/inhibin beta A chain isoform 1 mature form in human. UniProtKB:P08476-1, 311-426." [PMID:10320815, PMID:12213882, PMID:12456957, PMID:12960042, PMID:1537316, PMID:17456790, PMID:2575216, PMID:7890768, PMID:9884026, PRO:CNA]

Yes

modification



PR:000018295

activin/inhibin beta A chain proteolytic cleavage product

INHBA/ClvPrd


"An activin/inhibin beta A chain that has been processed by proteolytic cleavage." [PRO:DNx]


Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036539 mINHBA/iso:1/mature
UniProtKB:Q04998-1, 309-424
enablescontributes_to GO:0005102 signaling receptor binding PMID:1646080; PMID:7577669
GO:0046983 protein dimerization activity PMID:2133547
PR:000036540 hINHBA/iso:1/mature
UniProtKB:P08476-1, 311-426
acts_upstream_of_or_withinGO:0007166 cell surface receptor signaling pathway PMID:12456957
GO:0007267 cell-cell signaling PMID:12456957
GO:0009605 response to external stimulus PMID:10320815
GO:0030154 cell differentiation PMID:12456957
GO:0032925 regulation of activin receptor signaling pathway PMID:9884026
enablescontributes_to GO:0005102 signaling receptor binding PMID:7890768
GO:0046983 protein dimerization activity PMID:1537316
located_inGO:0005576 extracellular region PMID:12213882; PMID:2575216
GO:0032991 protein-containing complex PMID:12960042
GO:0043509 activin A complex PMID:7890768
GO:0043512 inhibin A complex PMID:17456790; PMID:7890768
PR:P08476-1 hINHBA/iso:1 acts_upstream_of_or_withinGO:0001541 ovarian follicle development PMID:9166111
GO:0007165 signal transduction PMID:3267209
GO:0007267 cell-cell signaling PMID:12456957
GO:0007399 nervous system development PMID:10320815
GO:0030154 cell differentiation PMID:12456957
GO:0050789 regulation of biological process PMID:12419948; PMID:3122219