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Protein Ontology report - activin/inhibin beta B chain
PR:000000217 - http://purl.obolibrary.org/obo/PR_000000217
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000217   
  PRO nameactivin/inhibin beta B chain 
  Synonyms
PRO-Short-label: EXACT:INHBB
Other: EXACT:activin beta-B chain
  Definition"An activin/inhibin beta subunit that is a translation product of the human INHBB gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000072 activin/inhibin beta subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000000217

activin/inhibin beta B chain

INHBB


"An activin/inhibin beta subunit that is a translation product of the human INHBB gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P09529

inhibin beta B chain (human)

hINHBB


"An activin/inhibin beta B chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P09529]


organism-sequence



PR:P09529-1

inhibin beta B chain isoform 1 (human)

hINHBB/iso:1


"An activin/inhibin beta B chain isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P09529]


organism-modification



PR:000036541

activin/inhibin beta B chain isoform 1 mature form (human)

hINHBB/iso:1/mature


"An activin/inhibin beta B chain isoform 1 mature form in human. UniProtKB:P09529-1, 293-407." [PMID:10320815, PMID:2575216, PMID:3122219, PMID:3754442, PRO:CNA]

Yes

organism-modification



PR:000054651

inhibin beta B chain O-glycosylated 1 (human)

hINHBB/OGlyco:1


"An inhibin beta B chain (human) that has been O-glycosylated at the residue equivalent to Ser-47 of the amino acid sequence represented by UniProtKB:P09529-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P09529-1, Ser-47, MOD:00002~GNO:G43417UB." [GlyGen:P09529-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000054652

inhibin beta B chain O-glycosylated 2 (human)

hINHBB/OGlyco:2


"An inhibin beta B chain (human) that has been O-glycosylated at the residue equivalent to Thr-35 of the amino acid sequence represented by UniProtKB:P09529-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P09529-1, Thr-35, MOD:00005~GNO:G43417UB." [GlyGen:P09529-1, PMID:30459171, PRO:DNx]


organism-gene



PR:P17491

inhibin beta B chain (rat)

rINHBB


"An activin/inhibin beta B chain that is encoded in the genome of rat." [OMA:P17491, PRO:DNx]


organism-gene



PR:P27093

inhibin beta B chain (chicken)

chick-INHBB


"An activin/inhibin beta B chain that is encoded in the genome of chicken." [OMA:P27093, PRO:DNx]


organism-gene



PR:Q04999

inhibin beta B chain (mouse)

mINHBB


"An activin/inhibin beta B chain that is encoded in the genome of mouse." [OMA:Q04999, PRO:DNx]


organism-sequence



PR:Q04999-1

inhibin beta B chain isoform 1 (mouse)

mINHBB/iso:1


"An activin/inhibin beta B chain isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q04999]


sequence



PR:000000417

activin/inhibin beta B chain isoform 1

INHBB/iso:1


"An activin/inhibin beta B chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09529-1 or a 1:1 ortholog thereof." [PMID:15319829, PRO:CNA, PRO:DAN]


organism-sequence



PR:P09529-1

inhibin beta B chain isoform 1 (human)

hINHBB/iso:1


"An activin/inhibin beta B chain isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P09529]


organism-modification



PR:000036541

activin/inhibin beta B chain isoform 1 mature form (human)

hINHBB/iso:1/mature


"An activin/inhibin beta B chain isoform 1 mature form in human. UniProtKB:P09529-1, 293-407." [PMID:10320815, PMID:2575216, PMID:3122219, PMID:3754442, PRO:CNA]

Yes

organism-sequence



PR:Q04999-1

inhibin beta B chain isoform 1 (mouse)

mINHBB/iso:1


"An activin/inhibin beta B chain isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q04999]


modification



PR:000021912

activin/inhibin beta B chain isoform 1, signal peptide removed form

INHBB/iso:1/SigPep-


"An activin/inhibin beta B chain isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000638

activin/inhibin beta B chain isoform 1 mature form

INHBB/iso:1/mature


"An activin/inhibin beta B chain isoform 1, signal peptide removed form that has been processed by subsequent removal of the propeptide. It is a subunit of activin B, inhibin B and activin AB complexes. Activin B is a homodimer of INHBB. Inhibin B is a dimer of INHA and INHBB. Activin AB is a dimer of INHBA and INHBB." [PMID:3754442]


organism-modification



PR:000036541

activin/inhibin beta B chain isoform 1 mature form (human)

hINHBB/iso:1/mature


"An activin/inhibin beta B chain isoform 1 mature form in human. UniProtKB:P09529-1, 293-407." [PMID:10320815, PMID:2575216, PMID:3122219, PMID:3754442, PRO:CNA]

Yes

modification



PR:000021927

activin/inhibin beta B chain proteolytic cleavage product

INHBB/ClvPrd


"An activin/inhibin beta B chain that has been processed by proteolytic cleavage." [PRO:DAN]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036541 hINHBB/iso:1/mature
UniProtKB:P09529-1, 293-407
acts_upstream_of_or_withinGO:0030154 cell differentiation PMID:10320815
GO:0046880 regulation of follicle-stimulating hormone secretion PMID:3122219
enablescontributes_to GO:0005102 signaling receptor binding PMID:3754442
GO:0005515 protein binding PMID:2575216
GO:0046983 protein dimerization activity PMID:2575216
located_inGO:0005576 extracellular region PMID:3122219