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Protein Ontology report - activin/inhibin beta C chain
PR:000000218 - http://purl.obolibrary.org/obo/PR_000000218
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000218   
  PRO nameactivin/inhibin beta C chain 
  Synonyms
PRO-Short-label: EXACT:INHBC
Other: EXACT:activin beta-C chain
  Definition"An activin/inhibin beta subunit that is a translation product of the human INHBC gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000072 activin/inhibin beta subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000000218

activin/inhibin beta C chain

INHBC


"An activin/inhibin beta subunit that is a translation product of the human INHBC gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P55103

inhibin beta C chain (human)

hINHBC


"An activin/inhibin beta C chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P55103]


organism-sequence



PR:P55103-1

inhibin beta C chain isoform 1 (human)

hINHBC/iso:1


"An inhibin beta C chain isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036545

inhibin beta C chain isoform 1 mature form (human)

hINHBC/iso:1/mature


"An inhibin beta C chain isoform 1 mature form in human. UniProtKB:P55103-1, 237-352." [PMID:11134153, PMID:12960042, PMID:16627954, PMID:7826378, PRO:CNA]

Yes

organism-gene



PR:P55104

inhibin beta C chain (mouse)

mINHBC


"An activin/inhibin beta C chain that is encoded in the genome of mouse." [OMA:P55104, PRO:DNx]


organism-sequence



PR:P55104-1

inhibin beta C chain isoform 1 (mouse)

mINHBC/iso:1


"An inhibin beta C chain isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:Q9WUK5

inhibin beta C chain (rat)

rINHBC


"An activin/inhibin beta C chain that is encoded in the genome of rat." [OMA:Q9WUK5, PRO:DNx]


sequence



PR:000000444

inhibin beta C chain isoform 1

INHBC/iso:1


"An activin/inhibin beta C chain that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55103-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]


organism-sequence



PR:P55103-1

inhibin beta C chain isoform 1 (human)

hINHBC/iso:1


"An inhibin beta C chain isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036545

inhibin beta C chain isoform 1 mature form (human)

hINHBC/iso:1/mature


"An inhibin beta C chain isoform 1 mature form in human. UniProtKB:P55103-1, 237-352." [PMID:11134153, PMID:12960042, PMID:16627954, PMID:7826378, PRO:CNA]

Yes

organism-sequence



PR:P55104-1

inhibin beta C chain isoform 1 (mouse)

mINHBC/iso:1


"An inhibin beta C chain isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


modification



PR:000021916

inhibin beta C chain isoform 1, signal peptide removed form

INHBC/iso:1/SigPep-


"An inhibin beta C chain isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000000642

inhibin beta C chain isoform 1 mature form

INHBC/iso:1/mature


"An inhibin beta C chain isoform 1, signal peptide removed form that has been processed by subsequent removal of the propeptide. It can form heterodimers with INHBB or INHBA." [PMID:11134153]


organism-modification



PR:000036545

inhibin beta C chain isoform 1 mature form (human)

hINHBC/iso:1/mature


"An inhibin beta C chain isoform 1 mature form in human. UniProtKB:P55103-1, 237-352." [PMID:11134153, PMID:12960042, PMID:16627954, PMID:7826378, PRO:CNA]

Yes

modification



PR:000021933

activin/inhibin beta C chain proteolytic cleavage product

INHBC/ClvPrd


"An activin/inhibin beta C chain that has been processed by proteolytic cleavage." [PRO:DAN]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036545 hINHBC/iso:1/mature
UniProtKB:P55103-1, 237-352
acts_upstream_of_or_withinGO:0032926 negative regulation of activin receptor signaling pathway PMID:12960042; PMID:16627954
enablescontributes_to GO:0005160 transforming growth factor beta receptor binding PMID:7826378
GO:0046983 protein dimerization activity PMID:11134153
located_inGO:0005576 extracellular region PMID:16627954; PMID:7826378
GO:0032991 protein-containing complex PMID:11134153; PMID:12960042