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Protein Ontology report - mitogen-activated protein kinase 1 isoform 1
PR:000000289 - http://purl.obolibrary.org/obo/PR_000000289
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000289   
  PRO namemitogen-activated protein kinase 1 isoform 1 
  Synonyms
PRO-Short-label: EXACT:MAPK1/iso:1
  Definition"A mitogen-activated protein kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28482-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000103 mitogen-activated protein kinase 1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification4                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000289 mitogen-activated protein kinase 1 isoform 1
MAPK1/iso:1

organism-sequence


PR:P28482-1 mitogen-activated protein kinase 1 isoform 1 (human)
hMAPK1/iso:1
Yes
organism-modification


PR:000026341 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human)
hMAPK1/iso:1/Phos:1
Yes
organism-sequence


PR:P63085-1 mitogen-activated protein kinase 1 isoform 1 (mouse)
mMAPK1/iso:1
Yes
organism-modification


PR:000036464 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (mouse)
mMAPK1/iso:1/Phos:1
Yes
modification


PR:000000454 mitogen-activated protein kinase 1 isoform 1 phosphorylated form
MAPK1/iso:1/PhosRes+

modification


PR:000000556 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1
MAPK1/iso:1/Phos:1

organism-modification


PR:000026341 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human)
hMAPK1/iso:1/Phos:1
Yes
organism-modification


PR:000036464 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (mouse)
mMAPK1/iso:1/Phos:1
Yes
organism-modification


PR:000036466 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (rat)
rMAPK1/iso:1/Phos:1
Yes
modification


PR:000025465 mitogen-activated protein kinase 1 isoform 1, initiator methionine removed form
MAPK1/iso:1/InitMet-

modification


PR:000000453 mitogen-activated protein kinase 1 isoform 1, initiator methionine removed acetylated form
MAPK1/iso:1/InitMet-/AcRes+

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026341 hMAPK1/iso:1/Phos:1
UniProtKB:P28482-1, Thr-185, MOD:00047|Tyr-187, MOD:00048		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:10958679
GO:0006935 chemotaxis PMID:10706854
GO:0007165 signal transduction PMID:1540184
enablesGO:0004672 protein kinase activity PMID:10706854
GO:0004707 MAP kinase activity PMID:10706854
GO:0005515 protein binding PMID:16291755
PR:000036464 mMAPK1/iso:1/Phos:1
UniProtKB:P63085-1, Thr-183, MOD:00047|Tyr-185, MOD:00048		 acts_upstream_of_or_withinGO:0000165 MAPK cascade PMID:8626447
GO:0006468 protein phosphorylation PMID:15284227
GO:0007165 signal transduction PMID:11684667
enablesGO:0004672 protein kinase activity PMID:14744933
GO:0004707 MAP kinase activity PMID:11684667; PMID:12223545; PMID:15314156; PMID:8626447
located_inGO:0005634 nucleus PMID:11726647; PMID:12925581; PMID:16251435
PR:000036466 rMAPK1/iso:1/Phos:1
UniProtKB:P63086-1, Thr-183, MOD:00047|Tyr-185, MOD:00048		 enablesGO:0042803 protein homodimerization activity PMID:9604935
PR:P28482-1 hMAPK1/iso:1 acts_upstream_of_or_withinGO:0006935 chemotaxis PMID:10706854
GO:0006950 response to stress PMID:10958679
GO:0007268 chemical synaptic transmission PMID:10706854
enablesNOT GO:0004707 MAP kinase activity PMID:10706854
PR:P63085-1 mMAPK1/iso:1 located_inGO:0005737 cytoplasm PMID:11726647; PMID:12223545