back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - mitogen-activated protein kinase 1 isoform 1
PR:000000289 - http://purl.obolibrary.org/obo/PR_000000289
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000289   
  PRO namemitogen-activated protein kinase 1 isoform 1 
  Synonyms
PRO-Short-label: EXACT:MAPK1/iso:1
  Definition"A mitogen-activated protein kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28482-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000103 mitogen-activated protein kinase 1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification4                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000289 mitogen-activated protein kinase 1 isoform 1
MAPK1/iso:1

organism-sequence


PR:P28482-1 mitogen-activated protein kinase 1 isoform 1 (human)
hMAPK1/iso:1
Yes
organism-modification


PR:000026341 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human)
hMAPK1/iso:1/Phos:1
Yes
organism-sequence


PR:P63085-1 mitogen-activated protein kinase 1 isoform 1 (mouse)
mMAPK1/iso:1
Yes
organism-modification


PR:000036464 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (mouse)
mMAPK1/iso:1/Phos:1
Yes
modification


PR:000000454 mitogen-activated protein kinase 1 isoform 1 phosphorylated form
MAPK1/iso:1/PhosRes+

modification


PR:000000556 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1
MAPK1/iso:1/Phos:1

organism-modification


PR:000026341 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (human)
hMAPK1/iso:1/Phos:1
Yes
organism-modification


PR:000036464 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (mouse)
mMAPK1/iso:1/Phos:1
Yes
organism-modification


PR:000036466 mitogen-activated protein kinase 1 isoform 1 phosphorylated 1 (rat)
rMAPK1/iso:1/Phos:1
Yes
modification


PR:000025465 mitogen-activated protein kinase 1 isoform 1, initiator methionine removed form
MAPK1/iso:1/InitMet-

modification


PR:000000453 mitogen-activated protein kinase 1 isoform 1, initiator methionine removed acetylated form
MAPK1/iso:1/InitMet-/AcRes+

Back to top
Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0000165 MAPK cascadePR:000036464 mMAPK1/iso:1/Phos:1 PMID:8626447
GO:0006468 protein phosphorylationPR:000036464 mMAPK1/iso:1/Phos:1 PMID:15284227
GO:0006915 apoptotic processPR:000026341 hMAPK1/iso:1/Phos:1 PMID:10958679
GO:0006935 chemotaxisPR:000026341 hMAPK1/iso:1/Phos:1 PMID:10706854
PR:P28482-1 hMAPK1/iso:1 PMID:10706854
GO:0006950 response to stressPR:P28482-1 hMAPK1/iso:1 PMID:10958679
GO:0007165 signal transductionPR:000026341 hMAPK1/iso:1/Phos:1 PMID:1540184
PR:000036464 mMAPK1/iso:1/Phos:1 PMID:11684667
GO:0007268 chemical synaptic transmissionPR:P28482-1 hMAPK1/iso:1 PMID:10706854

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0004672 protein kinase activityPR:000026341 hMAPK1/iso:1/Phos:1 PMID:10706854
PR:000036464 mMAPK1/iso:1/Phos:1 PMID:14744933
GO:0004707 MAP kinase activityPR:000026341 hMAPK1/iso:1/Phos:1 PMID:10706854
PR:000036464 mMAPK1/iso:1/Phos:1 PMID:11684667; PMID:12223545; PMID:15314156; PMID:8626447
NOT GO:0004707 MAP kinase activityPR:P28482-1 hMAPK1/iso:1 PMID:10706854
GO:0005515 protein bindingPR:000026341 hMAPK1/iso:1/Phos:1 PMID:16291755
GO:0042803 protein homodimerization activityPR:000036466 rMAPK1/iso:1/Phos:1 PMID:9604935

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:000036464 mMAPK1/iso:1/Phos:1 PMID:11726647; PMID:12925581; PMID:16251435
GO:0005737 cytoplasmPR:P63085-1 mMAPK1/iso:1 PMID:11726647; PMID:12223545