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Protein Ontology report - pituitary homeobox 2 isoform Ptx2A
PR:000000294 - http://purl.obolibrary.org/obo/PR_000000294
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000294   
  PRO namepituitary homeobox 2 isoform Ptx2A 
  Synonyms
PRO-Short-label: EXACT:PITX2/iso:Ptx2A
Other: EXACT:ARP1A | pituitary homeobox 2 isoform 1 | Pitx2a
  Definition"A pituitary homeobox 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99697-3 or a 1:1 ortholog thereof." [PMID:10585561, PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000117 pituitary homeobox 2
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000294
pituitary homeobox 2 isoform Ptx2A
PITX2/iso:Ptx2A
"A pituitary homeobox 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99697-3 or a 1:1 ortholog thereof." [PMID:10585561, PRO:CNA, PRO:DAN]

organism-sequence


PR:O93385-2
pituitary homeobox 2 isoform Ptx2A (chicken)
chick-PITX2/iso:Ptx2A
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of chicken." [PRO:DNx, UniProtKB:O93385]

organism-sequence


PR:P97474-3
pituitary homeobox 2 isoform Ptx2A (mouse)
mPITX2/iso:Ptx2A
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P97474]
Yes
organism-sequence


PR:Q99697-3
pituitary homeobox 2 isoform Ptx2A (human)
hPITX2/iso:Ptx2A
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99697]
Yes
organism-sequence


PR:Q9R0W1-2
pituitary homeobox 2 isoform Ptx2A (rat)
rPITX2/iso:Ptx2A
"A pituitary homeobox 2 isoform Ptx2A that is encoded in the genome of rat." [PRO:DNx, UniProtKB:Q9R0W1]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P97474-3 mPITX2/iso:Ptx2A acts_upstream_of_or_withinGO:0007266 Rho protein signal transduction PMID:11854422
NOT GO:0007368 determination of left/right symmetry PMID:10585561
GO:0030036 actin cytoskeleton organization PMID:11854422
GO:0043388 positive regulation of DNA binding MGI_ref:3796777; PMID:18458156
enablesGO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific MGI_ref:3796777; PMID:18458156
GO:0003677 DNA binding MGI_ref:3796777; PMID:18458156
GO:0003712 transcription coregulator activity MGI_ref:3796777; PMID:18458156
GO:0005515 protein binding MGI_ref:3796777; PMID:18458156
GO:0008134 transcription factor binding PMID:15385555
located_inGO:0005634 nucleus PMID:11854422
GO:0005634 nucleus PMID:11854422
PR:Q99697-3 hPITX2/iso:Ptx2A enablesGO:0005515 protein binding with PR:Q99697-2 PMID:11948188
GO:0008134 transcription factor binding PMID:16449236
located_inGO:0005634 nucleus PMID:16449236