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Protein Ontology report - retinoblastoma-like protein 1 isoform 1
PR:000000303 - http://purl.obolibrary.org/obo/PR_000000303
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000303   
  PRO nameretinoblastoma-like protein 1 isoform 1 
  Synonyms
PRO-Short-label: EXACT:RBL1/iso:1
  Definition"A retinoblastoma-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28749-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000118 retinoblastoma-like protein 1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000303
retinoblastoma-like protein 1 isoform 1
RBL1/iso:1
"A retinoblastoma-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28749-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]

organism-sequence


PR:P28749-1
retinoblastoma-like protein 1 isoform 1 (human)
hRBL1/iso:1
"A retinoblastoma-like protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-modification


PR:000036470
retinoblastoma-like protein 1 isoform 1 phosphorylated 1 (human)
hRBL1/iso:1/Phos:1
"A retinoblastoma-like protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046." [PMID:11884610, PRO:CNA]
Yes
organism-sequence


PR:Q64701-1
retinoblastoma-like protein 1 isoform Long (mouse)
mRBL1/iso:Long
"A retinoblastoma-like protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

modification


PR:000000458
retinoblastoma-like protein 1 isoform 1 phosphorylated form
RBL1/iso:1/PhosRes+
"A retinoblastoma-like protein 1 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]

modification


PR:000000559
retinoblastoma-like protein 1 isoform 1 phosphorylated 1
RBL1/iso:1/Phos:1
"A retinoblastoma-like protein 1 isoform 1 phosphorylated form in which the phosphorylation occurs in an RxL motif-dependent fashion by cyclin Cdk4. Example: UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046." [PMID:11884610, PRO:CNA, PRO:DAN]

organism-modification


PR:000036470
retinoblastoma-like protein 1 isoform 1 phosphorylated 1 (human)
hRBL1/iso:1/Phos:1
"A retinoblastoma-like protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046." [PMID:11884610, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036470 hRBL1/iso:1/Phos:1
UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046		 acts_upstream_of_or_withinGO:0051726 regulation of cell cycle PMID:11884610
enablesGO:0005515 protein binding PMID:11884610
NOT GO:0030308 negative regulation of cell growth PMID:11884610
PR:P28749-1 hRBL1/iso:1 acts_upstream_of_or_withinGO:0051726 regulation of cell cycle PMID:8319904
enablesGO:0005515 protein binding PMID:11884610
GO:0030308 negative regulation of cell growth PMID:11884610