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Protein Ontology report - retinoblastoma-like protein 2 isoform 1
PR:000000306 - http://purl.obolibrary.org/obo/PR_000000306
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000306   
  PRO nameretinoblastoma-like protein 2 isoform 1 
  Synonyms
PRO-Short-label: EXACT:RBL2/iso:1
  Definition"A retinoblastoma-like protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08999-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000119 retinoblastoma-like protein 2
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification4                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000306 retinoblastoma-like protein 2 isoform 1
RBL2/iso:1

organism-sequence


PR:Q08999-1 retinoblastoma-like protein 2 isoform 1 (human)
hRBL2/iso:1
Yes
organism-modification


PR:000036471 retinoblastoma-like protein 2 isoform 1 phosphorylated 1 (human)
hRBL2/iso:1/Phos:1
Yes
organism-modification


PR:000036472 retinoblastoma-like protein 2 isoform 1 phosphorylated 2 (human)
hRBL2/iso:1/Phos:2
Yes
organism-modification


PR:000036473 retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (human)
hRBL2/iso:1/Phos:3
Yes
organism-sequence


PR:Q64700-1 retinoblastoma-like protein 2 isoform 1 (mouse)
mRBL2/iso:1
Yes
organism-modification


PR:000036474 retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (mouse)
mRBL2/iso:1/Phos:3
Yes
modification


PR:000000459 retinoblastoma-like protein 2 isoform 1 phosphorylated form
RBL2/iso:1/PhosRes+

modification


PR:000000560 retinoblastoma-like protein 2 isoform 1 phosphorylated 1
RBL2/iso:1/Phos:1

organism-modification


PR:000036471 retinoblastoma-like protein 2 isoform 1 phosphorylated 1 (human)
hRBL2/iso:1/Phos:1
Yes
modification


PR:000000561 retinoblastoma-like protein 2 isoform 1 phosphorylated 2
RBL2/iso:1/Phos:2

organism-modification


PR:000036472 retinoblastoma-like protein 2 isoform 1 phosphorylated 2 (human)
hRBL2/iso:1/Phos:2
Yes
modification


PR:000000562 retinoblastoma-like protein 2 isoform 1 phosphorylated 3
RBL2/iso:1/Phos:3

organism-modification


PR:000036473 retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (human)
hRBL2/iso:1/Phos:3
Yes
organism-modification


PR:000036474 retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (mouse)
mRBL2/iso:1/Phos:3
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036471 hRBL2/iso:1/Phos:1
UniProtKB:Q08999-1, Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046		 acts_upstream_of_or_withinGO:0051726 regulation of cell cycle PMID:11042701; PMID:11157749; PMID:8710362
enablesNOT GO:0005515 protein binding PMID:11157749
NOT GO:0030308 negative regulation of cell growth PMID:11157749
PR:000036472 hRBL2/iso:1/Phos:2
UniProtKB:Q08999-1, Ser-672, MOD:00046		 acts_upstream_of_or_withinGO:0051726 regulation of cell cycle PMID:12006580
enablesGO:0005515 protein binding with PR:Q13309 cyclin-A/CDK2-associated protein p45 (human) PMID:12006580
NOT GO:0030308 negative regulation of cell growth PMID:12006580
PR:000036473 hRBL2/iso:1/Phos:3
UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047		 acts_upstream_of_or_withinGO:0051726 regulation of cell cycle PMID:11042701; PMID:11157749; PMID:8710362
enablesGO:0005515 protein binding with PR:Q16254 E2F-4 (human) PMID:11042701; PMID:11157749
PR:000036474 mRBL2/iso:1/Phos:3 located_inGO:0005667 transcription factor complex PMID:10082561
PR:Q08999-1 hRBL2/iso:1 enablesGO:0005515 protein binding PMID:8361765
PR:Q64700-1 mRBL2/iso:1 acts_upstream_of_or_withinGO:0051726 regulation of cell cycle PMID:10082561
enablesGO:0030308 negative regulation of cell growth PMID:10082561
located_inGO:0005634 nucleus PMID:10082561