back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - activin receptor type-1-like isoform 1
PR:000000316 - http://purl.obolibrary.org/obo/PR_000000316
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000316   
  PRO nameactivin receptor type-1-like isoform 1 
  Synonyms
PRO-Short-label: EXACT:ACVRL1/iso:1
Other: RELATED:ALK1
  Definition"An activin receptor type-1-like that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37023-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000126 activin receptor type-1-like
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000316 activin receptor type-1-like isoform 1
ACVRL1/iso:1

organism-sequence


PR:P37023-1 activin receptor type-1-like isoform 1 (human)
hACVRL1/iso:1
Yes
organism-sequence


PR:Q61288-1 activin receptor type-1-like isoform 1 (mouse)
mACVRL1/iso:1
Yes
Back to top
Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0001525 angiogenesisPR:P37023-1 hACVRL1/iso:1 PMID:12453878
PR:Q61288-1 mACVRL1/iso:1 PMID:10716993
GO:0006468 protein phosphorylationPR:P37023-1 hACVRL1/iso:1 PMID:9920917
PR:Q61288-1 mACVRL1/iso:1 PMID:14580334
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:Q61288-1 mACVRL1/iso:1 PMID:14580334
GO:0008015 blood circulationPR:P37023-1 hACVRL1/iso:1 PMID:9245985

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0004675 transmembrane receptor protein serine/threonine kinase activityPR:P37023-1 hACVRL1/iso:1 PMID:8242742; PMID:9245985
GO:0005025 transforming growth factor beta receptor activity, type IPR:P37023-1 hACVRL1/iso:1 PMID:8242742
GO:0016361 activin receptor activity, type IPR:P37023-1 hACVRL1/iso:1 PMID:8242742
GO:0046332 SMAD bindingPR:P37023-1 hACVRL1/iso:1 PMID:9920917
PR:Q61288-1 mACVRL1/iso:1 PMID:14580334
GO:0048185 activin bindingPR:P37023-1 hACVRL1/iso:1 PMID:8242742
GO:0050431 transforming growth factor beta bindingPR:P37023-1 hACVRL1/iso:1 PMID:8242742

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005886 plasma membranePR:P37023-1 hACVRL1/iso:1 PMID:8242742; PMID:8397373
GO:0009986 cell surfacePR:P37023-1 hACVRL1/iso:1 PMID:8242742