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Protein Ontology report - smad5
PR:000000372 - http://purl.obolibrary.org/obo/PR_000000372
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000372   
  PRO namesmad5 
  Synonyms
PRO-Short-label: EXACT:SMAD5
Gene-based: RELATED:MADH5
Other: EXACT:dwarfin-C | Dwf-C | JV5-1 | MAD homolog 5 | mothers against DPP homolog 5 | SMAD 5 | SMAD family member 5 | Smad5
  Definition"A BMP receptor-regulated smad protein that is a translation product of the human SMAD5 gene or a 1:1 ortholog thereof." [PMID:10708949] 
  PRO Categorygene 
  ParentPR:000000038 BMP receptor-regulated smad protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence2                                                  Organism-Sequence 3                                        
         Modification4                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000000372 smad5
SMAD5

organism-gene


PR:P97454 mothers against decapentaplegic homolog 5 (mouse)
mSMAD5

organism-sequence


PR:P97454-1 mothers against decapentaplegic homolog 5 isoform 1 (mouse)
mSMAD5/iso:1
Yes
organism-modification


PR:000036563 smad5 isoform 1 phosphorylated 1 (mouse)
mSMAD5/iso:1/Phos:1
Yes
organism-gene


PR:Q56I99 mothers against decapentaplegic homolog 5 (chicken)
chick-SMAD5

organism-gene


PR:Q99717 mothers against decapentaplegic homolog 5 (human)
hSMAD5

organism-sequence


PR:000029962 smad5 isoform 2 (human)
hSMAD5/iso:2
Yes
organism-sequence


PR:Q99717-1 mothers against decapentaplegic homolog 5 isoform 1 (human)
hSMAD5/iso:1
Yes
organism-modification


PR:000036562 smad5 isoform 1 phosphorylated 1 (human)
hSMAD5/iso:1/Phos:1
Yes
organism-modification


PR:000049289 mothers against decapentaplegic homolog 5, initiator methionine removed form (human)
hSMAD5/InitMet-

organism-modification


PR:000049290 mothers against decapentaplegic homolog 5, initiator methionine removed phosphorylated 1 (human)
hSMAD5/InitMet-/Phos:1

organism-gene


PR:Q9R1V3 mothers against decapentaplegic homolog 5 (rat)
rSMAD5

organism-gene


PR:Q9W7E7 mothers against decapentaplegic homolog 5 (zebrafish)
z-SMAD5

sequence


PR:000000477 smad5 isoform 1
SMAD5/iso:1

organism-sequence


PR:P97454-1 mothers against decapentaplegic homolog 5 isoform 1 (mouse)
mSMAD5/iso:1
Yes
organism-modification


PR:000036563 smad5 isoform 1 phosphorylated 1 (mouse)
mSMAD5/iso:1/Phos:1
Yes
organism-sequence


PR:Q99717-1 mothers against decapentaplegic homolog 5 isoform 1 (human)
hSMAD5/iso:1
Yes
organism-modification


PR:000036562 smad5 isoform 1 phosphorylated 1 (human)
hSMAD5/iso:1/Phos:1
Yes
modification


PR:000000580 smad5 isoform 1 phosphorylated form
SMAD5/iso:1/PhosRes+

modification


PR:000000661 smad5 isoform 1 phosphorylated 1
SMAD5/iso:1/Phos:1

organism-modification


PR:000036562 smad5 isoform 1 phosphorylated 1 (human)
hSMAD5/iso:1/Phos:1
Yes
organism-modification


PR:000036563 smad5 isoform 1 phosphorylated 1 (mouse)
mSMAD5/iso:1/Phos:1
Yes
modification


PR:000026652 smad5 isoform 1, initiator methionine removed form
SMAD5/iso:1/InitMet-

sequence


PR:000000478 smad5 isoform 2
SMAD5/iso:2

organism-sequence


PR:000029962 smad5 isoform 2 (human)
hSMAD5/iso:2
Yes
modification


PR:000018297 smad5, initiator methionine removed form
SMAD5/InitMet-

modification


PR:000026652 smad5 isoform 1, initiator methionine removed form
SMAD5/iso:1/InitMet-

organism-modification


PR:000049289 mothers against decapentaplegic homolog 5, initiator methionine removed form (human)
hSMAD5/InitMet-

organism-modification


PR:000049290 mothers against decapentaplegic homolog 5, initiator methionine removed phosphorylated 1 (human)
hSMAD5/InitMet-/Phos:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000029962 hSMAD5/iso:2 enablesNOT GO:0046332 SMAD binding PMID:10845932
PR:000036562 hSMAD5/iso:1/Phos:1
UniProtKB:Q99717-1, Ser-463/Ser-465, MOD:00046		 acts_upstream_of_or_withinGO:0030509 BMP signaling pathway PMID:8637600
enablesGO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:8673135
PR:000036563 mSMAD5/iso:1/Phos:1
UniProtKB:P97454-1, Ser-463/Ser-465, MOD:00046		 acts_upstream_of_or_withinGO:0030509 BMP signaling pathway PMID:16522160
located_inGO:0005634 nucleus PMID:10504300; PMID:9759503
PR:P97454-1 mSMAD5/iso:1 acts_upstream_of_or_withinGO:0007165 signal transduction PMID:16765933
GO:0030509 BMP signaling pathway PMID:16522160; PMID:16765933
located_inGO:0005737 cytoplasm PMID:10504300
PR:Q99717-1 hSMAD5/iso:1 acts_upstream_of_or_withinGO:0030509 BMP signaling pathway PMID:8673135
enablesGO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:8673135