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gene
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 PR:000000372 |
   smad5
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   SMAD5
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  "A BMP receptor-regulated smad protein that is a translation product of the human SMAD5 gene or a 1:1 ortholog thereof." [PMID:10708949]
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organism-gene
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 PR:P97454 |
   mothers against decapentaplegic homolog 5 (mouse)
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   mSMAD5
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  "A smad5 that is encoded in the genome of mouse." [OMA:P97454, PRO:DNx]
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organism-sequence
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 PR:P97454-1 |
   mothers against decapentaplegic homolog 5 isoform 1 (mouse)
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   mSMAD5/iso:1
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  "A smad5 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000036563 |
   smad5 isoform 1 phosphorylated 1 (mouse)
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   mSMAD5/iso:1/Phos:1
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  "A smad5 isoform 1 phosphorylated 1 in mouse. UniProtKB:P97454-1, Ser-463/Ser-465, MOD:00046." [PMID:10504300, PMID:15331632, PMID:16522160, PMID:9759503, PRO:CNA]
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 Yes | 
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organism-gene
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 PR:Q56I99 |
   mothers against decapentaplegic homolog 5 (chicken)
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   chick-SMAD5
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  "A smad5 that is encoded in the genome of chicken." [OMA:Q56I99, PRO:DNx, UniProtKB:Q56I99]
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organism-gene
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 PR:Q99717 |
   mothers against decapentaplegic homolog 5 (human)
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   hSMAD5
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  "A smad5 that is encoded in the genome of human." []
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organism-sequence
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 PR:000029962 |
   smad5 isoform 2 (human)
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   hSMAD5/iso:2
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  "A smad5 isoform 2 that is encoded in the genome of human." [PRO:DAN]
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 Yes | 
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organism-sequence
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 PR:Q99717-1 |
   mothers against decapentaplegic homolog 5 isoform 1 (human)
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   hSMAD5/iso:1
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  "A smad5 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000036562 |
   smad5 isoform 1 phosphorylated 1 (human)
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   hSMAD5/iso:1/Phos:1
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  "A smad5 isoform 1 phosphorylated 1 in human. UniProtKB:Q99717-1, Ser-463/Ser-465, MOD:00046." [PMID:8637600, PMID:8673135, PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000049289 |
   mothers against decapentaplegic homolog 5, initiator methionine removed form (human)
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   hSMAD5/InitMet-
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  "A mothers against decapentaplegic homolog 5 (human) that has had the initiator methionine removed. UniProtKB:Q99717, 2-465." [PRO:DNx, Reactome:R-HSA-201431]
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organism-modification
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 PR:000049290 |
   mothers against decapentaplegic homolog 5, initiator methionine removed phosphorylated 1 (human)
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   hSMAD5/InitMet-/Phos:1
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  "A mothers against decapentaplegic homolog 5 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 463 and 465 of the amino acid sequence represented by UniProtKB:Q99717. UniProtKB:Q99717, 2-465, Ser-463/Ser-465, MOD:00046." [PRO:DNx, Reactome:R-HSA-201432, Reactome:R-HSA-201473]
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organism-gene
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 PR:Q9R1V3 |
   mothers against decapentaplegic homolog 5 (rat)
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   rSMAD5
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  "A smad5 that is encoded in the genome of rat." [OMA:Q9R1V3, PRO:DNx]
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organism-gene
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 PR:Q9W7E7 |
   mothers against decapentaplegic homolog 5 (zebrafish)
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   z-SMAD5
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  "A smad5 that is encoded in the genome of zebrafish." [OMA:Q9W7E7, PRO:DNx]
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sequence
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 PR:000000477 |
   smad5 isoform 1
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   SMAD5/iso:1
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  "A smad5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99717-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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 PR:P97454-1 |
   mothers against decapentaplegic homolog 5 isoform 1 (mouse)
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   mSMAD5/iso:1
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  "A smad5 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000036563 |
   smad5 isoform 1 phosphorylated 1 (mouse)
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   mSMAD5/iso:1/Phos:1
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  "A smad5 isoform 1 phosphorylated 1 in mouse. UniProtKB:P97454-1, Ser-463/Ser-465, MOD:00046." [PMID:10504300, PMID:15331632, PMID:16522160, PMID:9759503, PRO:CNA]
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 Yes | 
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organism-sequence
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 PR:Q99717-1 |
   mothers against decapentaplegic homolog 5 isoform 1 (human)
 |
   hSMAD5/iso:1
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  "A smad5 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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 Yes | 
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organism-modification
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 PR:000036562 |
   smad5 isoform 1 phosphorylated 1 (human)
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   hSMAD5/iso:1/Phos:1
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  "A smad5 isoform 1 phosphorylated 1 in human. UniProtKB:Q99717-1, Ser-463/Ser-465, MOD:00046." [PMID:8637600, PMID:8673135, PRO:CNA]
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 Yes | 
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modification
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 PR:000000580 |
   smad5 isoform 1 phosphorylated form
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   SMAD5/iso:1/PhosRes+
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  "A smad5 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
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modification
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 PR:000000661 |
   smad5 isoform 1 phosphorylated 1
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   SMAD5/iso:1/Phos:1
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  "A smad5 isoform 1 phosphorylated form in which the phosphorylation occurs at the C-terminal SSxS motif as a result of the activation of the bone morphogenetic protein (BMP) signaling pathway. Example: UniProtKB:Q99717-1, Ser-463/Ser-465, MOD:00046." [PMID:8637600]
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organism-modification
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 PR:000036562 |
   smad5 isoform 1 phosphorylated 1 (human)
 |
   hSMAD5/iso:1/Phos:1
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  "A smad5 isoform 1 phosphorylated 1 in human. UniProtKB:Q99717-1, Ser-463/Ser-465, MOD:00046." [PMID:8637600, PMID:8673135, PRO:CNA]
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 Yes | 
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organism-modification
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|
 PR:000036563 |
   smad5 isoform 1 phosphorylated 1 (mouse)
 |
   mSMAD5/iso:1/Phos:1
 |
  "A smad5 isoform 1 phosphorylated 1 in mouse. UniProtKB:P97454-1, Ser-463/Ser-465, MOD:00046." [PMID:10504300, PMID:15331632, PMID:16522160, PMID:9759503, PRO:CNA]
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 Yes | 
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modification
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 PR:000026652 |
   smad5 isoform 1, initiator methionine removed form
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   SMAD5/iso:1/InitMet-
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  "A smad5 isoform 1 that has had the initiator methionine removed." [PRO:DNx]
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sequence
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 PR:000000478 |
   smad5 isoform 2
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   SMAD5/iso:2
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  "A smad5 that is a translation product of a transcript comprising intron 6 generating a C-terminus truncated MH2 domain and a unique C-terminus sequence lacking the SSxS motif necessary for SMAD activation." [EST:AA169504, PMID:10845932, PRO:CNA, PRO:DAN]
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organism-sequence
 |


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 PR:000029962 |
   smad5 isoform 2 (human)
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   hSMAD5/iso:2
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  "A smad5 isoform 2 that is encoded in the genome of human." [PRO:DAN]
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 Yes | 
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modification
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 PR:000018297 |
   smad5, initiator methionine removed form
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   SMAD5/InitMet-
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  "A smad5 that has had the initiator methionine removed." [PRO:DNx]
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modification
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 PR:000026652 |
   smad5 isoform 1, initiator methionine removed form
 |
   SMAD5/iso:1/InitMet-
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  "A smad5 isoform 1 that has had the initiator methionine removed." [PRO:DNx]
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organism-modification
 |


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 PR:000049289 |
   mothers against decapentaplegic homolog 5, initiator methionine removed form (human)
 |
   hSMAD5/InitMet-
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  "A mothers against decapentaplegic homolog 5 (human) that has had the initiator methionine removed. UniProtKB:Q99717, 2-465." [PRO:DNx, Reactome:R-HSA-201431]
 |

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|  |  |  |  |  |  |  |  |
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organism-modification
 |


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 PR:000049290 |
   mothers against decapentaplegic homolog 5, initiator methionine removed phosphorylated 1 (human)
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   hSMAD5/InitMet-/Phos:1
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  "A mothers against decapentaplegic homolog 5 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 463 and 465 of the amino acid sequence represented by UniProtKB:Q99717. UniProtKB:Q99717, 2-465, Ser-463/Ser-465, MOD:00046." [PRO:DNx, Reactome:R-HSA-201432, Reactome:R-HSA-201473]
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